Hidenori Kanda Takeharu Kaneda Yuta Nagai Norimoto Urakawa Kazumasa Shimizu
Journal of Veterinary Medical Science 80(5) 846-8502018年5月 [査読有り]
Exposure to chronic hypoxic conditions causes various gastric diseases, including gastric ulcers. It has been suggested that gastric smooth muscle contraction is associated with aerobic metabolism. However, there are no reports on the association ...
Takeharu Kaneda Hidenori Kanda Tsuyoshi Tajima Norimoto Urakawa Kazumasa Shimizu
Journal of Veterinary Medical Science 80(2) 341-3452018年2月 [査読有り]
The mechanism of imidazole-induced contraction on the bovine tracheal smooth muscle was investigated. Imidazole induced muscle contraction in a concentration-dependent manner on bovine, porcine and guinea-pig tracheas, but not in rat or mouse. In ...
Takashi Hirano Takeharu Kaneda Hiroshi Ozaki Masatoshi Hori
Journal of Veterinary Medical Science 80(2) 219-2242018年2月 [査読有り]
Angiotensin II (100 nM) induced bi-phasic increases in cytosolic Ca2+ level ([Ca2+]i) through the activation of angiotensin II type 1 receptor. Pharmacological examinations using 10 µM verapamil, 30 µM La3+, and 1 µM thapsigargin indicated that th...
Journal of Veterinary Medical Science 80(2) 225-2342018年2月 [査読有り]
Pectenotoxin-2 (PCTX-2) is one of the polyether macrolide toxins isolated from scallops involved in diarrheic shellfish poisoning via actin depolymerization. In the present study, we examined the bioactive mechanism of PCTX-2 in smooth muscle cell...
学長
獣医学部