各教員の業績及び学位 | 日本獣医生命科学大学

論文

Genetic and chemical targeting of the ATPase complex TIP48 and 49 impairs acute myeloid leukemia.

Ayuna Hattori Emi Takamatsu-Ichihara Yoshiki Yamamoto Shuhei Fujita Kazutsune Yamagata Takuo Katsumoto Yukino Machida Haruka Shinohara Ryo Murakami Issay Kitabayashi

Leukemia 2023年7月 [査読有り]

The chromatin-associated AAA+ ATPases Tip48 and Tip49 are the core components of various complexes implicated in diverse nuclear events such as DNA repair and gene regulation. Although they are frequently overexpressed in many human cancers, their...

Alteration in molecular properties during establishment and passaging of endometrial carcinoma patient-derived xenografts

Toshio Imai Hiroshi Yoshida Yukino Machida Mizuki Kuramochi Hitoshi Ichikawa Takashi Kubo Mami Takahashi Tomoyasu Kato

Scientific Reports 13(1) 2023年5月 [査読有り]

Abstract

Patient-derived xenograft (PDX) tumor models are known to maintain the genomic and phenotypic profiles, including the histopathological structures, of the parental tumors. On the other hand, unique enrichment of single-nucleotide variant...

Inhibition of the mitochondria-shaping protein Opa1 restores sensitivity to Gefitinib in a lung adenocarcinomaresistant cell line.

Masafumi Noguchi Susumu Kohno Anna Pellattiero Yukino Machida Keitaro Shibata Norihito Shintani Takashi Kohno Noriko Gotoh Chiaki Takahashi Atsushi Hirao Luca Scorrano Atsuko Kasahara

Cell death & disease 14(4) 241-241 2023年4月 [査読有り]

Drug resistance limits the efficacy of chemotherapy and targeted cancer treatments, calling for the identification of druggable targets to overcome it. Here we show that the mitochondria-shaping protein Opa1 participates in resistance against the ...

Pulmonary solid adenocarcinoma in a dog

Masaki Michishita Naoki Hanari Hitomi Oda Tomokazu Nagashima Yukino Machida Yuji Hamamoto Kyoichi Tamura Daigo Azakami Kazuhiko Ochiai Akihiro Mori

Journal of Comparative Pathology 201 100-104 2023年2月 [査読有り]

A 12-year-old castrated male Beagle dog presented with a 1-month history of progressive loss of appetite and cough. One month after the initial visit, a detailed clinical examination was performed due to weight loss and persistent cough. Computed ...

Infective endocarditis with systemic bacterial embolism caused by Staphylococcus aureus in a free-ranging Amami rabbit (Pentalagus furnessi)

Masaki Konnai Masami Yamamoto Keiko Ito Hanae Yamabe Takuya E Kishimoto Hiroshi Aoki Yukino Machida Masaki Michishita Makoto Haritani Hisashi Yoshimura

Journal of Comparative Pathology 201 23-27 2023年2月 [査読有り]

MISC

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Targeting driver mutations and critical factors in hematological and solid cancers

Issay Kitabayashi Yukiko Aikawa Kazutsune Yamagata Takuo Katsumoto Yutaka Shima Akihiko Yokoyama Yukino Machida Haruka Shinohara Yoko Ogawara Shuhei Fujita Makoto Nakagawa Koichi Ichimura Daisuke Honma Hironori Matsunaga Kazushi Araki

CANCER SCIENCE 113 1256-1256 2022年2月

FRS2b fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis

Yasuto Takeuchi Natsuko Kimura Takahiko Murayama Yukino Machida Daisuke Iejima Tatsunori Nishimura Yuming Wang Mizuki Yamamoto Naoki Itano Junichiro Inoue Koichi Akashi Hideyuki Saya Masahiko Kuroda Issay Kitabayashi Arinobu Tojo Noriko Gotoh

CANCER SCIENCE 113 994-994 2022年2月

ドライバー変異と必須因子を標的とした分子標的治療法の開発を目指して

北林一生相川祐規子山形和恒勝本拓夫島豊横山明彦町田雪乃篠原悠小川原陽子藤田修平中川亮市村幸一本間大輔松永大典荒木一司

日本癌学会学術総会抄録集(Web) 80th 2021年

猫の膵外分泌腺癌株化細胞Fpacc-E由来のsphere形成細胞の特性解析

兵頭あかね町田雪乃落合和彦落合和彦小野沢栄里呰上大吾道下正貴道下正貴

日本獣医学会学術集会講演要旨集 164th (CD-ROM) 2021年

犬の乳腺腫瘍におけるnestinの発現と悪性挙動への関与

吉村久志山本昌美岸本拓也岸本拓也町田雪乃道下正貴落合和彦中川貴之松田陽子高橋公正石渡俊行

日本獣医学会学術集会講演要旨集 164th (CD-ROM) 2021年