小柳円

研究者氏名	小柳円
	コヤナギマドカ
URL	https://kaken.nii.ac.jp/d/r/00543399.ja.html
所属	日本獣医生命科学大学
部署	応用生命科学部動物科学科
職名	准教授
J-Global ID	201601013591655505

研究キーワード

ストレス ,HIV-1 ,CTL

研究分野

ライフサイエンス / 免疫学 /

経歴

12 >

2020年4月

現在

日本獣医生命科学大学応用生命科学部動物科学科准教授

2016年4月

2020年3月

日本獣医生命科学大学応用生命科学部動物科学科講師

2014年4月

2016年3月

日本獣医生命科学大学応用生命科学部動物科学科助教

2009年2月

2014年3月

熊本大学エイズ学研究センター特任助教

2006年3月

2009年1月

St.Jude Children’s Research Hospital Department of Immunology 研究員

学歴

2000年4月

2004年3月

東京女子医科大学大学院医学研究科微生物学免疫学分野

1998年4月

2000年3月

北里大学大学院医科学研究科生体機能医科学群

論文

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A comparative study of colorimetric cell proliferation assays in immune cells

Madoka Koyanagi So Kawakabe Yutaka Arimura

CYTOTECHNOLOGY 68(4) 1489-1498 2016年8月 [査読有り]

Cell proliferation assays are basic and essential techniques for assessing cellular function. Various colorimetric assays, such as MTT-, WST-1-, and resazurin-based assays, are available; however, studies directly comparing the suitability of each...

Different Effects of Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutations on Cytotoxic T Lymphocyte Recognition between HIV-1 Subtype B and Subtype A/E Infections

Nozomi Kuse Mohammad Arif Rahman Hayato Murakoshi Giang Van Tran Takayuki Chikata Madoka Koyanagi Kinh Van Nguyen Hiroyuki Gatanaga Shinichi Oka Masafumi Takiguchi

JOURNAL OF VIROLOGY 89(14) 7363-7372 2015年7月 [査読有り]

The effect of antiretroviral drug resistance mutations on cytotoxic T lymphocyte (CTL) recognition has been analyzed in HIV-1 subtype B infections, but it remains unclear in infections by other HIV-1 subtypes that are epidemic in countries where a...

Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes

Hayato Murakoshi Tomohiro Akahoshi Madoka Koyanagi Takayuki Chikata Takuya Naruto Rie Maruyama Yoshiko Tamura Naoki Ishizuka Hiroyuki Gatanaga Shinichi Oka Masafumi Takiguchi

JOURNAL OF VIROLOGY 89(10) 5330-5339 2015年5月 [査読有り]

Identification and characterization of CD8(+) T cells effectively controlling HIV-1 variants are necessary for the development of AIDS vaccines and for studies of AIDS pathogenesis, although such CD8(+) T cells have been only partially identified....

Effects of protein tyrosine phosphatase-PEST are reversed by Akt in T cells

Yutaka Arimura Kazuhiko Shimizu Madoka Koyanagi Junji Yagi

CELLULAR SIGNALLING 26(12) 2721-2729 2014年12月 [査読有り]

T cell activation is regulated by a balance between phosphorylation and dephosphorylation that is under the control of kinases and phosphatases. Here, we examined the role of a non-receptor-type protein tyrosine phosphatase, PTP-PEST, using retrov...

HIV Subtype Influences HLA- B*07: 02-Associated HIV Disease Outcome

Henrik N. Kloverpris Emily Adland Madoka Koyanagi Anette Stryhn Mikkel Harndahl Philippa C. Matthews Roger Shapiro Bruce D. Walker Thumbi Ndung'u Christian Brander Masafumi Takiguchi Soren Buus Philip Goulder

AIDS RESEARCH AND HUMAN RETROVIRUSES 30(5) 468-475 2014年5月 [査読有り]

Genetic polymorphisms within the MHC encoding region have the strongest impact on HIV disease progression of any in the human genome and provide important clues to the mechanisms of HIV immune control. Few analyses have been undertaken of HLA alle...