This study examined the mechanism of vasorelaxation induced by dimethyl sulfoxide (DMSO) in endothelium-intact and -denuded rat aorta. DMSO (0.1-3%) inhibited phenylephrine (PE, 1 mu mol/l)-induced contraction in a dose-dependent manner. However, ...
N. Sasaki   M. Nakamura   S. Soeta   
GENETICS AND MOLECULAR RESEARCH 13(3) 6855-6864 2014年 [査読有り]
Malate dehydrogenase (MDH) plays crucial roles in energy and cellular metabolism. In this study, we describe the identification and characterization of cytosolic MDH (MDH1) and mitochondrial MDH (MDH2) in liver of domestic cat (Felis catus). To cl...
Journal of Veterinary Medical Science 75(10) 1383-1387 2013年 [査読有り]
Retinol-binding protein 4 (RBP4) is a specific transporter of retinol and was recently identified as an adipokine potentially involved in type 2 diabetes in humans and rodents. However, the function and structure of feline RBP4 have not been repor...
JOURNAL OF VETERINARY MEDICAL SCIENCE 74(10) 1277-1282 2012年10月 [査読有り]
To elucidate the role of glycogen in the contraction of tracheal smooth muscle, we investigated the changes in the glycogen contents of the bovine trachea during contractions induced by high K+ and hypoxia (achieved by bubbling N-2, instead of O-2...
Tracy P. Torres   Noriyasu Sasaki   E. Patrick Donahue   Brooks Lacy   Richard L. Printz   Alan D. Cherrington   Judith L. Treadway   Masakazu Shiota   
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 337(3) 610-620 2011年6月 [査読有り]
The effects of a glycogen phosphorylase inhibitor (GPI) and metformin (MT) on hepatic glucose fluxes (mu mol . kg(-1) . min(-1)) in the presence of basal and 4-fold basal levels of plasma glucagon were investigated in 18-h fasted conscious dogs. C...