Tracy P. Torres Noriyasu Sasaki E. Patrick Donahue Brooks Lacy Richard L. Printz Alan D. Cherrington Judith L. Treadway Masakazu Shiota
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 337(3) 610-620 2011年6月 [査読有り]
The effects of a glycogen phosphorylase inhibitor (GPI) and metformin (MT) on hepatic glucose fluxes (mu mol . kg(-1) . min(-1)) in the presence of basal and 4-fold basal levels of plasma glucagon were investigated in 18-h fasted conscious dogs. C...
JOURNAL OF VETERINARY MEDICAL SCIENCE 71(2) 189-194 2009年2月 [査読有り]
Adiponectin is an adipokine that is specifically expressed in adipose tissues, directly sensitizes the body to insulin via specific receptors and its decreased plasma concentration is responsible for insulin resistance in obese humans. Diabetes is...
Tracy P. Torres ReEtta L. Catlin Robert Chan Yuka Fujimoto Noriyasu Sasaki Richard L. Printz Christopher B. Newgard Masakazu Shiota
DIABETES 58(1) 78-86 2009年1月 [査読有り]
OBJECTIVE-We examined in 20-week-old Zucker diabetic fatty (ZDF) rats whether restoration of hepatic glucokinase (GK) expression would alter hepatic glucose flux and improve hyper-glycemia.
RESEARCH DESIGN AND METHODS-ZDF rats were treated at vari...
E. Magori M. Nakamura A. Inoue A. Tanaka N. Sasaki H. Fukuda H. Mizutani T. Sako N. Kimura T. Arai
Research in Veterinary Science 78(1) 39-44 2005年2月 [査読有り]
The activities of the enzymes in the malate-aspartate shuttle were measured in peripheral leucocytes of spontaneous type 1 diabetic dogs and cats treated with insulin injections. In the diabetic dogs and cats, fasting plasma glucose concentrations...
H Shibata N Sasaki T Honjoh Ohishi, I M Takiguchi K Ishioka M Ahmed M Soliman K Kimura M Saito
JOURNAL OF VETERINARY MEDICAL SCIENCE 65(11) 1207-1211 2003年11月 [査読有り]
Leptin is a protein synthesized and secreted primarily by adipose tissue. The blood leptin concentration is known to reflect body fat content in rodents, humans and dogs, and thereby is useful for quantitative assessment of obesity. In the present...
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獣医学部