K. Kimura K. Kimura N. Sasaki A. Asano J. Mizukami S. Kayahashi T. Kawada T. Fushiki M. Morimatsu T. Yoshida M. Saito
Hormone and Metabolic Research 32(3) 91-96 2000年 [査読有り]
Wild-type or mutated human β3-adrenergic receptor (Trp64Arg) cDNAs were stably expressed in mouse 3T3-L1 cells. Saturation binding study using a β- adrenergic ligand revealed that there was no significant difference in the receptor density and the...
Noriyasu Sasaki Eiji Uchida Masayoshi Niiyama Toshihide Yoshida Masayuki Saito
Journal of Veterinary Medical Science 60(4) 465-469 1998年4月 [査読有り]
The aim of this study was to evaluate the effectiveness of β3-adrenergic agonists for the treatment and prevention of obesity in the dog. When a selective β-adrenergic agonist. CL316,243 (0.1 mg/kg). was given orally to adult beagles every day for...
Journal of Veterinary Medical Science 60(4) 459-463 1998年4月 [査読有り]
It is known that in rodents and humans the β3-adrenergic receptor (β3-AR) is present primarily in adipocytes and plays a significant role in the adrenergic stimulation of lipolysis. We examined the expression of β3-AR mRNA in the dog and the lipom...
I. Nagase N. Sasaki K. Tsukazaki T. Yoshida M. Morimatsu M. Saito
Japanese Journal of Veterinary Research 42(3-4) 137-146 1994年12月 [査読有り]
When mammals are exposed to a cold environment for a long time, the capacity of nonshivering thermogenesis by brown adipose tissue (BAT) increases in association with the increased expression of some specific proteins and tissue hyperplasia, which...
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獣医学部