田島剛

研究者氏名	田島剛

URL
所属	日本獣医生命科学大学
部署	獣医学部獣医学科
職名	講師
J-Global ID	201601001389201936

論文

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PDE4 and PDE5 regulate cyclic nucleotide contents and relaxing effects on carbachol-induced contraction in the bovine abomasum

Takeharu Kaneda Yuuki Kido Tsuyoshi Tajima Norimoto Urakawa Kazumasa Shimizu

JOURNAL OF VETERINARY MEDICAL SCIENCE 77(1) 15-19 2015年1月 [査読有り]

The effects of various selective phosphodiesterase (PDE) inhibitors on carbachol (CCh)-induced contraction in the bovine abomasum were investigated. Various selective PDE inhibitors, vinpocetine (type 1), erythro-9-(2-hydroxy-3-nonyl) adenine (EHN...

Antitumor Effect of Bevacizumab in a Xenograft Model of Canine Hemangiopericytoma

Masaki Michishita Tatsuya Uto Ryota Nakazawa Hisashi Yoshimura Kikumi Ogihara Yuko Naya Tsuyoshi Tajima Daigo Azakami Seigo Kishikawa Toshiro Arai Kimimasa Takahashi

JOURNAL OF PHARMACOLOGICAL SCIENCES 121(4) 339-342 2013年4月 [査読有り]

Canine hemangiopericytoma (CHP) is characterized by frequent local recurrence and increased invasiveness. Vascular endothelial growth factor (VEGF) is a key regulator of angiogenesis in tumors. The aim of the present study was to investigate the e...

Key Role of Glycogen Storage in High K+-Induced Contraction of the Smooth Muscles of the Bovine Trachea

Takeharu Kaneda Tomoe Fujieda Yuta Eto Yuta Nagai Noriyasu Sasaki Tsuyoshi Tajima Norimoto Urakawa Kazumasa Shimizu

JOURNAL OF VETERINARY MEDICAL SCIENCE 74(10) 1277-1282 2012年10月 [査読有り]

To elucidate the role of glycogen in the contraction of tracheal smooth muscle, we investigated the changes in the glycogen contents of the bovine trachea during contractions induced by high K+ and hypoxia (achieved by bubbling N-2, instead of O-2...

EP2 and EP4 receptors on muscularis resident macrophages mediate LPS-induced intestinal dysmotility via iNOS upregulation through cAMP/ERK signals

Tsuyoshi Tajima Takahisa Murata Kosuke Aritake Yoshihiro Urade Masaki Michishita Toshiyuki Matsuoka Shuh Narumiya Hiroshi Ozaki Masatoshi Hori

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 302(5) G524-G534 2012年3月 [査読有り]

Tajima T, Murata T, Aritake K, Urade Y, Michishita M, Matsuoka T, Narumiya S, Ozaki H, Hori M. EP2 and EP4 receptors on muscularis resident macrophages mediate LPS-induced intestinal dysmotility via iNOS upregulation through cAMP/ERK signals. Am J...

Effects of Papaverine on Twitches in Mouse Diaphragm

Takeharu Kaneda Ryutaro Hayasaka Yuta Nagai Tsuyoshi Tajima Norimoto Urakawa Shinjiro Nakajyo Kazumasa Shimizu

PHARMACOLOGY 86(5-6) 273-280 2010年 [査読有り]

This study examined the inhibitory effects of papaverine on twitches directly elicited by electrical stimulation of the mouse diaphragm. Papaverine (3-100 mu m) inhibited twitches in a dose-dependent manner. Papaverine increased the cyclic adenosi...