大坂元久

研究者氏名	大坂元久
	オオサカモトヒサ
URL
所属	日本獣医生命科学大学獣医保健看護学科獣医保健看護学基礎部門
部署
職名	教授
学位	博士(医学)(日本医科大学)
J-Global ID	200901063101290352

プロフィール

東京大学理学部数学卒、日本医科大学卒

研究キーワード

遺伝情報学 ,不整脈出現パタ-ンの解析 ,心拍変動の非線形解析 ,Genetic Informatics ,Pattern Analysis of Occurrence of Arrhythmia ,Nonlinear Analysis of Heart Rate Variability

研究分野

自然科学一般 / 応用数学、統計数学 / 非線形科学
自然科学一般 / 数学基礎 / 非線形科学
ライフサイエンス / 循環器内科学 /

学歴

1985年

日本医科大学医学部医学科

1985年

日本医科大学

受賞

1999年

日本医科大学医学会奨学賞

1997年

福田記念医療技術振興財団研究助成金賞

1996年

日本医科大学同窓会医学研究助成金賞

1994年

上原記念生命科学財団助成金賞

論文

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Sudden cardiac arrest recorded during Holier monitoring: Prevalence, antecedent electrical events, and outcomes

Eiichi Watanabe Teruhisa Tanabe Motohisa Osaka Akiko Chishaki Bonpei Takase Shinichi Niwano Ichiro Watanabe Kaoru Sugi Takao Katoh Kan Takayanagi Koushi Mawatari Minoru Horie Ken Okumura Hiroshi Inoue Hirotsugu Atarashi Iwao Yamaguchi Susumu Nagasawa Kazuo Moroe Itsuo Kodama Tsuneaki Sugimoto Yoshifusa Aizawa

HEART RHYTHM 11(8) 1418-1425 2014年8月 [査読有り]

BACKGROUND Causative arrhythmias of sudden cardiac arrest (SCA) are changing in this age of improved coronary care.
OBJECTIVE The purpose of this study was to examine the frequency of terminal arrhythmias and the electrical events prior to SCA.
ME...

Age-adjusted level of circulating elastin as a cardiovascular risk factor in medical check-up individuals

Hiroyuki Yamanaka Motohisa Osaka Morimasa Takayama Kazuo Munakata Jun Nejima Masahiko Katayama

JOURNAL OF CARDIOVASCULAR MEDICINE 15(5) 364-370 2014年5月 [査読有り]

Aims
The level of circulating soluble elastin (CSE) is reported to increase proportionally with the degree of clinical atherosclerosis; however, its diagnostic use is limited because CSE also increases with age. We aimed to investigate whether alt...

Proposal of an improved relative risk measure that estimates prevention as well as promotion of disease

大坂元久

Bulletin of Nippon Veterinary and Life Science University 63 67-70 2014年 [査読有り]

Probability theory predicts that chunking into groups of three or four items increases short-term memory capacity

大坂元久

Applied Mathematics 5(10) 1474-1484 2014年 [査読有り]

A modified FitzHugh-Nagumo model for cardiac instabilities: The replacement of a conductance variable with Ca current as a slow variable

Motohisa Osaka

AIP Conference Proceedings 1518 571-578 2013年 [査読有り]

The FitzHugh-Nagumo model of nerve conduction is also used as a model of cardiac excitability. We propose the replacement of a gating variable of the conductance of K+ current with Ca2+ current as a slow variable of the model, in which plays a key...

MISC

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Potentiated sympathetic nervous and renin-angiotensin systems reduce nonlinear correlation between sympathetic activity and blood pressure in conscious spontaneously hypertensive rats

K Sakata H Kumagai M Osaka T Onami T Matsuura M Imai T Saruta

CIRCULATION 106(5) 620-625 2002年7月

Background-Patients with a reduced nonlinear component of heart rate regulation have a poorer outcome.
Methods and Results-We investigated whether a nonlinear correlation between renal sympathetic nerve activity (RSNA) and blood pressure or renal ...

Quantitative analysis of termination of vagally induced canine atrial fibrillation by mutual information

S Shimizu M Osaka H Saitoh H Atarashi T Takano

JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION 65(2) 111-116 2001年2月

Atrial fibrillation (AF) is often described as a disorganized phenomenon, but many features that qualitatively suggest an underlying order have recently been reported. The present study aimed to disclose this underlying order of AF in a quantitati...

Local box-counting to determine fractal dimension of high-order chaos

M Osaka N Ito

INTERNATIONAL JOURNAL OF MODERN PHYSICS C 11(8) 1519-1526 2000年12月

To determine the attractor dimension of chaotic dynamics, the box-counting method has the difficulty in getting accurate estimates because the boxes are not weighted by their relative probabilities. We present a new method to minimize this difficu...

Symbolic Strings and Spatial 1/f Spectra 「(共著)」

Physica D 125(1/2) 142-154 1999年

Depressed Heart Rate Variability and Arterial Baroreflex in Conscious Transgenic Mice with Overexpression of Cardiac Gsa 「(共著)」

Circulation Research 82 416-423 1998年