H. Yoshimura   M. Michishita   K. Ohkusu-Tsukada   K. Takahashi   
VETERINARY PATHOLOGY 48(1) 313-321 2011年1月 [査読有り]
The aims of this study were to determine whether the appearance of stromal myofibroblasts and the expression of tenascin-C (Tn-C) correlate with the grade of malignancy in canine mammary tumors and to determine the main cellular source of Tn-C in ...
Kozo Ohkusu-Tsukada   Shigeki Ohta   Yutaka Kawakami   Masahiro Toda   
INTERNATIONAL JOURNAL OF CANCER 128(1) 119-131 2011年1月 [査読有り]
Use of adequate adjuvant is necessary for induction of effective antitumor immune responses. To develop an effective adjuvant for cancer immunotherapy, we selected formalin-inactivated (f)-HSV as an adjuvant component, and analyzed the mechanisms ...
A subcutaneous mass arising in the right gluteal area of an 11-year-old female shih tzu dog was surgically excised. Histologically, the mass was composed of small round or ovoid neoplastic cells that were arranged in nests of various sizes. The ne...
EUROPEAN JOURNAL OF IMMUNOLOGY 40(4) 1011-1021 2010年4月 [査読有り]
Cancer-induced immunotolerance mediated by inducible Treg (iTreg) is a major obstacle to cancer immunotherapy. In a basic study of immunotolerance, injection of an endogenous superantigen, i.e. the minor lymphocyte stimulatory (Mls)-1(a), into spe...
JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION 22(2) 305-309 2010年3月
A lipid-rich carcinoma of the mammary gland was diagnosed in a female Djungarian hamster (Phodopus sungorus), which was kept as an indoor pet. The animal underwent surgery for a primary tumor arising in the mammary gland at the age of 16 months, a...