Baculovirus display systems have been utilized for cell-specific gene transfer, regenerative medicine, and as vaccine vectors. In particular, baculovirus particles displaying surface antigens have been used as vaccines against some parasites and v...
MATSUO Shiro MORITA Tatsushi IMAI Soichi IKE Kazunori
Journal of Veterinary Epidemiology 18(2) 124-129 2014年 [査読有り]
The hearts, diaphragms, hind legs, and back muscles of 64 Japanese sika deer (Cervus nippon centralis) caught in a mountainous area of Hyogo Prefecture, Japan, were examined for Sarcocystis infection by detecting sarcocysts. Sarcocysts were detect...
Akira Ito Tohru Gotanda Naomi Himeno Noriko Itchoda Noriko Tabayashi Kazunori Ike Chihiro Sugimoto Takeshi Matsumura
Avian Pathology 42(3) 215-220 2013年6月 [査読有り]
We developed a transgenic potato (TrP/R7) expressing the recombinant R7 (rR7) antigen for use as an oral vaccine to protect against a chicken protozoan disease, chicken leucocytozoonosis. The TrP/R7 potato was produced by Agrobacterium tumefaciens...
Masaki Uchida Kotomi Nagashima Yui Akatsuka Takashi Murakami Akira Ito Soichi Imai Kazunori Ike
PARASITOLOGY RESEARCH 112(2) 655-663 2013年2月 [査読有り]
Neospora caninum is an obligate intracellular protozoan parasite that causes severe neuromuscular diseases, repeated abortion, stillbirth, and congenital infection in livestock and companion animals. The development of an effective vaccine against...
Jinhua Dong Takahiro Otsuki Tatsuya Kato Tetsuya Kohsaka Kazunori Ike Enoch Y. Park
PLOS ONE 8(1) e53264 2013年1月 [査読有り]
Neosporosis, caused by an intracellular parasite, Neospora caninum, is an infectious disease primarily of cattle and dogs. It occurs worldwide and causes huge damages to dairy farms. In this study, we immunized mice with recombinant surface-associ...
K Ike T Komatsu T Murakami Y Kato M Takahashi Y Uchida S Imai
JOURNAL OF VETERINARY MEDICAL SCIENCE 67(5) 515-520 2005年5月
As the comparative study was carried out on the susceptibility by the pursuit of parasitemia among the Djungarian, Syrian, and Chinese hamsters as well as BALB/c mice infected with the Syrian hamster-adapted Babesia microti strain, and Djungarian ...
JOURNAL OF VETERINARY MEDICAL SCIENCE 67(5) 521-524 2005年5月
Mice were inoculated intraperitoneally wih 34 different types of vegetable juices, and interferon-gamma (IFN-gamma) and interleukin-4 (IL-4) were measured as markers for the induction of Th1 and Th2 cells, respectively. Serum IFN-gamma level was m...
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