Journal of diabetes research 2019 8153140-8153140 2019年 [査読有り]
A variety of animal models of diabetes mellitus (DM) are required to study the genetics and pathophysiology of DM. We established a novel rat strain showing nonobese type 2 diabetes with enlarged kidneys from the LEA.PET-pet congenic strain and na...
Kentaro Katayama Mao Kuriki Tomoyo Kamiya Yuki Tochigi Hiroetsu Suzuki
Biochemical and biophysical research communications 499(3) 459-465 2018年5月 [査読有り]
Extracellular matrix (ECM) constitutes a proper micro-environment for cell proliferation, migration and differentiation, as well as playing pivotal roles in developmental processes including endochondral ossification. Cartilage ECM is mainly compo...
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 69(5) 245-258 2017年6月 [査読有り]
A congenital reduction in the number of nephrons is a critical risk factor for both onset of chronic kidney disease (CKD) and its progression to end-stage kidney disease (ESKD). Hypoplastic kidney (HPK) rats have only about 20% of the normal numbe...
Biochemical and biophysical research communications 486(4) 958-964 2017年5月 [査読有り]
Male hypogonadism (hgn/hgn) rats show testicular hypoplasia accompanied by dysplastic development of seminiferous tubules due to loss-of-function mutation of the gene encoding Astrin, which is required for mitotic progression in the division cycle...
Homeobox genes play important roles in craniofacial morphogenesis. However, the characteristics of the transcription factor Hoxc during palate formation remain unclear. We examined the immunolocalization patterns of Hoxc5, Hoxc4, and Hoxc6 in pala...
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獣医学部