木邊量子

研究者氏名	木邊量子

URL
所属	日本獣医生命科学大学
部署	獣医学部獣医学科獣医微生物学研究室
職名
J-Global ID	201601004330667957

研究分野

ライフサイエンス / 獣医学 /

論文

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Longevity in Mice Is Promoted by Probiotic-Induced Suppression of Colonic Senescence Dependent on Upregulation of Gut Bacterial Polyamine Production

Mitsuharu Matsumoto Shin Kurihara Ryoko Kibe Hisashi Ashida Yoshimi Benno

PLOS ONE 6(8) e23652 2011年8月 [査読有り]

Background: Chronic low-grade inflammation is recognized as an important factor contributing to senescence and age-related diseases. In mammals, levels of polyamines (PAs) decrease during the ageing process; PAs are known to decrease systemic infl...

Trp53 negatively regulates autoimmunity via the STAT3-Th17 axis

Shuzhong Zhang Mingquan Zheng Ryoko Kibe Yunping Huang Luis Marrero Samantha Warren Arthur W. Zieske Tomoo Iwakuma Jay K. Kolls Yan Cui

FASEB JOURNAL 25(7) 2387-2398 2011年7月 [査読有り]

Emerging evidence suggests that the tumor suppressor p53 is also a crucial regulator for many physiological processes. Previous observations indicate that p53 suppresses inflammation by inhibiting inflammatory antigen-presenting cells. To investig...

Regulatory role of B-1B cells in chronic colitis

Yasuyo Shimomura Emiko Mizoguchi Ken Sugimoto Ryoko Kibe Yoshimi Benno Atsushi Mizoguchi Atul K. Bhan

INTERNATIONAL IMMUNOLOGY 20(6) 729-737 2008年6月 [査読有り]

According to the 'hygiene hypothesis', enhanced microbial exposure due to early childhood infections leads to a reduction of T(h)2-mediated allergic diseases and inflammatory bowel disease. To begin to elucidate the mechanisms underlying...

Modifying effects of fermented brown rice on fecal microbiota in rats

Keiko Kataoka Ryoko Kibe Tomomi Kuwahara Mari Hagiwara Hideki Arimochi Teruaki Iwasaki Yoshimi Benno Yoshinari Ohnishi

ANAEROBE 13(5-6) 220-227 2007年10月 [査読有り]

Brown rice fermented by Aspergillus oryzae (FBRA) is a fiber-rich food. Effects of dietary administration of FBRA on rat fecal microbiota composition were examined. Male Wistar rats were fed a basal diet or a 5% FBRA- or 10% FBRA-containing diet, ...

Effect of herbal medicine Juzentaihoto on hepatic and intestinal heat shock gene expression requires intestinal microflora in mouse

Miho Kato Atsushi Ishige Naoko Anjiki Masahiro Yamamoto Yoshifumi Irie Mitsue Taniyama Ryoko Kibe Junichiro Oka Yoshimi Benno Kenji Watanabe

WORLD JOURNAL OF GASTROENTEROLOGY 13(16) 2289-2297 2007年4月 [査読有り]

AIM: To evaluate the role of intestinal microflora in the effects of multi-herbal medicine on gene expression in the gut and liver.
METHODS: The multi-herbal medicine Juzentaihoto (JTX) was administered to five germ-free mice and regular mice for ...