Massimo Bottini Federica D'Annibale Andrea Magrini Fabio Cerignoli Yutaka Arimura Marcia I. Dawson Enrico Bergamaschi Nicola Rosato Antonio Bergamaschi Tomas Mustelin
INTERNATIONAL JOURNAL OF NANOMEDICINE 2(2) 227-233 2007年 [査読有り]
To enhance diagnostic or therapeutic efficacy, novel nanomaterials must be engineered to function in biologically relevant environments, be visible by conventional fluorescent microscopy, and have multivalent loading capacity for easy detection or...
INTERNATIONAL IMMUNOLOGY 18(12) 1681-1690 2006年12月 [査読有り]
Comparative studies using T(h)2-prone BALB/c and T(h)1-prone C57BL/6 mice were performed to clarify the influence of genetic background on T-h cell differentiation. The results showed IL-4, the production of which is induced by IL-2, to be much mo...
We previously reported that V beta 3(+) CD4(+) T cells maintained a protracted expansion, with the phenotypes of memory Th2 cells, for 30 days in C57BL/6 (B6) mice implanted with SEA-containing mini-osmotic pumps. In the present Study, we followed...
Y Arimura F Shiroki S Kuwahara H Kato U Dianzani T Uchiyama J Yagi
JOURNAL OF BIOLOGICAL CHEMISTRY 279(12) 11408-11416 2004年3月 [査読有り]
Both CD28 and its relative, inducible costimulator ( ICOS), have a binding motif for phosphatidylinositol 3-kinase (PI3K) in their cytoplasmic tail, and the binding of PI3K leads to activation of a serine/threonine kinase, Akt. The role of Akt in ...
M Koyanagi K Imanishi Y Arimura H Kato J Yagi T Uchiyama
INTERNATIONAL IMMUNOLOGY 16(2) 315-326 2004年2月 [査読有り]
To determine the levels of maturation and differentiation of murine CD4 single-positive (SP) T cells, we compared the secondary responses of staphylococcal enterotoxin A (SEA)-induced neonatal thymic, adult thymic and adult splenic CD4 SP T cell b...
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