氏家誠

研究者氏名	氏家誠

所属	日本獣医生命科学大学
部署	獣医学部獣医学科獣医感染症学研究室
職名	准教授
学位	博士（医学）(名古屋市立大学)
J-Global ID	201601020286651431

研究分野

ライフサイエンス / ウイルス学 /

論文

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Host Adaptation and the Alteration of Viral Properties of the First Influenza A/H1N1pdm09 Virus Isolated in Japan.

Akira Ainai Hideki Hasegawa Masatsugu Obuchi Takato Odagiri Makoto Ujike Masayuki Shirakura Eri Nobusawa Masato Tashiro Hideki Asanuma

PloS one 10(6) e0130208 2015年 [査読有り]

A/Narita/1/2009 (A/N) was the first H1N1 virus from the 2009 pandemic (H1pdm) to be isolated in Japan. To better understand and predict the possible development of this virus strain, the effect of passaging A/N was investigated in Madin-Darby cani...

Hemagglutination mediated by the spike protein of cell-adapted bovine torovirus.

Kozue Shimabukuro Makoto Ujike Toshihiro Ito Hiroshi Tsunemitsu Hitoshi Oshitani Fumihiro Taguchi

Archives of virology 158(7) 1561-6 2013年7月 [査読有り]

Bovine torovirus (BToV)-Aichi, recently isolated in cultured cells, showed hemagglutination (HA) activity, although the virus has a truncated hemagglutinin-esterase (HE) protein, judging from its gene structure, indicating the existence of another...

Two palmitylated cysteine residues of the severe acute respiratory syndrome coronavirus spike (S) protein are critical for S incorporation into virus-like particles, but not for M-S co-localization.

Makoto Ujike Cheng Huang Kazuya Shirato Shutoku Matsuyama Shinji Makino Fumihiro Taguchi

The Journal of general virology 93(Pt 4) 823-828 2012年4月 [査読有り]

The endodomain of several coronavirus (CoV) spike (S) proteins contains palmitylated cysteine residues and enables co-localization and interaction with the CoV membrane (M) protein. Depalmitylation of mouse hepatitis virus S proteins abolished thi...

Increased replication of respiratory syncytial virus in the presence of cytokeratin 8 and 18.

Kazuya Shirato Makoto Ujike Miyuki Kawase Shutoku Matsuyama

Journal of medical virology 84(2) 365-70 2012年2月 [査読有り]

Previously, it was reported that productive viral infection, viral protein synthesis, and viral RNA replication of respiratory syncytial virus (RSV) operated efficiently in two human epithelial cell lines (HEp-2 and A549), but not in a human mast-...

Mutation in the cytoplasmic retrieval signal of porcine epidemic diarrhea virus spike (S) protein is responsible for enhanced fusion activity.

Kazuya Shirato Madoka Maejima Shutoku Matsuyama Makoto Ujike Ayako Miyazaki Natsumi Takeyama Hidetoshi Ikeda Fumihiro Taguchi

Virus research 161(2) 188-93 2011年11月 [査読有り]

Murine-adapted porcine epidemic diarrhea virus (PEDV), MK-p10, shows high neurovirulence and increased fusion activity compared with a non-adapted MK strain. MK-p10 S protein had four mutations relative to the original virus S, and one of these (H...