氏家誠

研究者氏名	氏家誠

所属	日本獣医生命科学大学
部署	獣医学部獣医学科獣医感染症学研究室
職名	准教授
学位	博士（医学）(名古屋市立大学)
J-Global ID	201601020286651431

研究分野

ライフサイエンス / ウイルス学 /

論文

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Role of proteases in the release of porcine epidemic diarrhea virus from infected cells.

Kazuya Shirato Shutoku Matsuyama Makoto Ujike Fumihiro Taguchi

Journal of virology 85(15) 7872-80 2011年8月 [査読有り]

Porcine epidemic diarrhea virus (PEDV), a causative agent of pig diarrhea, requires a protease(s) for multicycle replication in cultured cells. However, the potential role of proteases in the infection process remains unclear. In order to explore ...

Rapid discrimination of oseltamivir-resistant 275Y and -susceptible 275H substitutions in the neuraminidase gene of pandemic influenza A/H1N1 2009 virus by duplex one-step RT-PCR assay.

Mina Nakauchi Makoto Ujike Masatsugu Obuchi Emi Takashita Ikuyo Takayama Miho Ejima Kunihiro Oba Nami Konomi Takato Odagiri Masato Tashiro Tsutomu Kageyama

Journal of medical virology 83(7) 1121-7 2011年7月 [査読有り]

Pandemic influenza A/H1N1 2009 (A/H1N1pdm) virus caused significant outbreaks worldwide last year (2009). A number of oseltamivir-resistant A/H1N1pdm viruses possessing an H275Y substitution in the neuraminidase (NA) protein were reported sporadic...

Mumefural and related HMF derivatives from Japanese apricot fruit juice concentrate show multiple inhibitory effects on pandemic influenza A (H1N1) virus

Nongluk Sriwilaijaroen Akio Kadowaki Yuriko Onishi Nobuki Gato Makoto Ujike Takato Odagiri Masato Tashiro Yasuo Suzuki

Food chemistry 127(1) 1-9 2011年7月 [査読有り]

Fruit-juice concentrate of Japanese apricot (Prunus mume Sieb. et Zucc.) has been shown to be effective against influenza A infection in MOCK cells. In this study, we isolated five components from the fruit-juice concentrate of Japanese apricot, 5...

Monitoring and characterization of oseltamivir-resistant pandemic (H1N1) 2009 virus, Japan, 2009-2010.

Makoto Ujike Miho Ejima Akane Anraku Kozue Shimabukuro Masatsugu Obuchi Noriko Kishida Xu Hong Emi Takashita Seiichiro Fujisaki Kazuyo Yamashita Hiroshi Horikawa Yumiko Kato Akio Oguchi Nobuyuki Fujita Masato Tashiro Takato Odagiri

Emerging infectious diseases 17(3) 470-9 2011年3月 [査読有り]

To monitor and characterize oseltamivir-resistant (OR) pandemic (H1N1) 2009 virus with the H275Y mutation, we analyzed 4,307 clinical specimens from Japan by neuraminidase (NA) sequencing or inhibition assay; 61 OR pandemic (H1N1) 2009 viruses wer...

Molecular evolutionary analysis of the influenza A(H1N1)pdm, May-September, 2009: temporal and spatial spreading profile of the viruses in Japan.

Teiichiro Shiino Nobuhiko Okabe Yoshinori Yasui Tomimasa Sunagawa Makoto Ujike Masatsugu Obuchi Noriko Kishida Hong Xu Emi Takashita Akane Anraku Reiko Ito Teruko Doi Miho Ejima Hiromi Sugawara Hiroshi Horikawa Shuji Yamazaki Yumiko Kato Akio Oguchi Nobuyuki Fujita Takato Odagiri Masato Tashiro Haruo Watanabe

PloS one 5(6) e11057 2010年6月 [査読有り]

BACKGROUND: In March 2009, pandemic influenza A(H1N1) (A(H1N1)pdm) emerged in Mexico and the United States. In Japan, since the first outbreak of A(H1N1)pdm in Osaka and Hyogo Prefectures occurred in the middle of May 2009, the virus had spread ov...