小林優多郎

研究者氏名	小林優多郎

URL
所属	日本獣医生命科学大学
部署	応用生命科学部食品科学科
職名	講師
学位	博士（農学）(九州大学)
J-Global ID	201701016920401931

研究分野

ライフサイエンス / 食品科学 /

経歴

2017年4月

現在

日本獣医生命科学大学助教

2015年4月

2017年3月

香川大学医学部博士研究員

学歴

2012年4月

2015年3月

九州大学大学院生物資源環境科学府生物産業創成専攻

2010年4月

2012年3月

九州大学大学院生物資源環境科学府生命機能科学専攻

2006年4月

2010年3月

九州大学農学部生物資源環境学科

論文

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NMR Spectroscopic and Quantum Mechanical Analyses of Enhanced Solubilization of Hesperidin by Theasinensin A

Ruge Cao Yutaro Kobayashi Airi Nonaka Yuji Miyata Kazunari Tanaka Takashi Tanaka Toshiro Matsui

PHARMACEUTICAL RESEARCH 32(7) 2301-2309 2015年7月 [査読有り]

The use of hesperidin in the pharmaceutical field is limited by its aqueous insolubility. The effects of natural compounds in tea on the solubility of hesperidin were evaluated and the underlying mechanism was investigated by nuclear-magnetic reso...

The Anti-atherosclerotic Dipeptide, Trp-His, Reduces Intestinal Inflammation through the Blockade of L-Type Ca2+ Channels

Yutaro Kobayashi Jennifer Kovacs-Nolan Toshiro Matsui Yoshinori Mine

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 63(26) 6041-6050 2015年7月 [査読有り]

Trp-His, the anti-atherosclerotic dipeptide, exerted an antiproliferative effect on vascular smooth muscle cells by L-type Ca2+ channel blocker-like effect. The beneficial potential by the blockade of Ca2+ channels on chronic intestinal inflammati...

Oral Administration of Hen Egg White Ovotransferrin Attenuates the Development of Colitis Induced by Dextran Sodium Sulfate in Mice

Yutaro Kobayashi Prithy Rupa Jennifer Kovacs-Nolan Patricia V. Turner Toshiro Matsui Yoshinori Mine

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 63(5) 1532-1539 2015年2月 [査読有り]

Ovotransferrin (OVT), one of the major hen egg white proteins, was shown to possess antimicrobial and antioxidant activities in vitro. However, there is no information regarding the in vivo preventative effect in chronic inflammatory diseases such...

Inhibition of calcium-calmodulin complex formation by vasorelaxant basic dipeptides demonstrated by in vitro and in silico analyses

Thanutchaporn Kumrungsee Tomomi Saiki Sayaka Akiyama Kentaro Nakashima Mitsuru Tanaka Yutaro Kobayashi Toshiro Matsui

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1840(10) 3073-3078 2014年10月 [査読有り]

Background: Tryptophan-histidine (Trp-His) was found to suppress the activity of the Ca2+/calmodulin (CaM)-dependent protein kinases II (CaMKII), which requires the Ca2+-CaM complex for an initial activation. In this study, we attempted to clarify...

Inhibition of calcium-calmodulin complex formation by vasorelaxant basic dipeptides demonstrated by in vitro and in silico analyses.

Kumrungsee T Saiki T Akiyama S Nakashima K Tanaka M Kobayashi Y Matsui T

Biochimica et biophysica acta 1840(10) 3073-3078 2014年10月 [査読有り]