MOLECULAR MEDICINE REPORTS 3(4) 669-672 2010年7月 [査読有り]
Poloxamer block copolymers have been studied in multiple applications as drug delivery systems (DDS). These A-B-A amphiphilic block copolymers up-regulate the expression of selected genes in cells and alter genetic responses to antineoplastic agen...
Ubiquitous free radical production occurs continuously in cells and tissues. Glutathione is the most abundant mammalian antioxidant, and is synthesized by glutathione synthetase (GSS). Therefore, GSS plays an important role in defending the cell a...
MOLECULAR MEDICINE REPORTS 2(5) 749-752 2009年9月 [査読有り]
Dialysis is the single most important therapy for chronic kidney disease. However, protein adsorption onto hemodialysis membranes promotes clot formation. The aim of the present Study was to develop a surface-modified membrane which suppresses pro...