SURFACE AND INTERFACE ANALYSIS 48(11) 1185-1189 2016年11月
The applicability of internal additives for mass scale calibration in time-of-flight secondary ion mass spectrometry (TOF-SIMS) was studied. Relation between the ions selected for mass scale calibration and the relative mass accuracy of the target...
SURFACE AND INTERFACE ANALYSIS 48(11) 1175-1180 2016年11月
The damage of polymer surfaces caused by the high energy primary ion beams of TOF-SIMS was examined using Ar cluster ions. Polymer damage, the damage of secondary ions detected from the polystyrene surface and the damage layer formed by the Bi-3 p...
SURFACE AND INTERFACE ANALYSIS 48(11) 1096-1099 2016年11月
Amyloid beta (A) adsorption onto lipid membranes depending on the condition of a lipid was investigated by means of time-of-flight secondary ion mass spectrometry (ToF-SIMS). A aggregation depending on the different hardness of lipid membrane has ...
Shusuke Nakano   Yuta Yokoyama   Satoka Aoyagi   Naoyuki Himi   John S. Fletcher   Nicholas P. Lockyer   Alex Henderson   John C. Vickerman   
BIOINTERPHASES 11(2) 02A307 2016年6月 [査読有り]
Time-of-flight secondary ion mass spectrometry (ToF-SIMS) provides detailed chemical structure information and high spatial resolution images. Therefore, ToF-SIMS is useful for studying biological phenomena such as ischemia. In this study, in orde...
Amyloid beta (A beta) peptides are considered to be strongly related to Alzheimer's disease. A beta peptides form a beta-sheet structure on hard lipid membranes and it would aggregate to form amyloid fibrils, which are toxic to cells. However, the...