YUKIO OZAKI

(尾崎行男)

Profile Information

Affiliation: School of Medicine Faculty of Medicine, Fujita Health University

Degree: 博士(医学）(Erasmus University)

J-GLOBAL ID: 201501019151234916
researchmap Member ID: 7000012704

BRIEF BIOGRAPHY:
While Prof. Dr. Yukio Ozaki is an interventional cardiologist having specialty in the field of acute myocardial infarction (Ozaki Y. et al; CVIT expert consensus document on primary PCI for AMI in 2018. Cardiovasc Interv Ther. 2018;33:178-203), coronary imaging such as OCT, IVUS, NIRS, angioscopy, CT angiography as well as structural heart disease (SHD). While Dr. Yukio Ozaki is the first Japanese fellow under the supervision of Prof. Patrick W. Serruys in the Thoraxcenter Erasmus University Rotterdam, he defended his thesis entitled “Clinical Application of IVUS and QCA to Assess PCI and Atherosclerosis” at Erasmus University Rotterdam. Based on his Rotterdam experience, Prof. Dr. Yukio Ozaki proposed for the first time that intact fibrous cap ACS (IFC-ACS) by OCT and angioscopy would be plaque erosion (EHJ 2011), reported firstly integrated backscatter IVUS defined thin cap fibroatheroma (TCFA) in comparison with OCT (Circ J 2015), initially examine the fate of incomplete stent apposition (ISA) in DES by OCT (EHJ 2010). While Yukio Ozaki, Sadako Motoyama and Jagat Narula initially reported that positive remodeling (PR) and low attenuation plaque (LAP) are crucial factors in ACS lesions by CT angiography, they published these features could predict the occurrence of future ACS and play a role in the long-term prognosis for the first time (JACC 2007, JACC 2009 & JACC 2015). Subsequently, Dr. Ozaki’s CITATION INDEX has reached 7,214 by Pure System in Elsevier in December 2019.

Research Interests

Research History

Aug, 2017 - Present

センター長, 心臓血管センター, 藤田保健衛生大学病院
Feb, 2016 - Present

副院長 (特定機能病院・臨床研究・病診連携(院外)・経営改善担当), 藤田保健衛生大学病院
Nov, 2010 - Present

客員教授, ｶﾘﾌｫﾙﾆｱ大学ｱｰﾊﾞｲﾝ校
Apr, 2007 - Present

主任教授, 循環器内科講座, 藤田保健衛生大学
Apr, 2014 - May, 2015

医学部教務委員長, 藤田保健衛生大学

Education

Apr, 1975 - Mar, 1981

School of Medicine, Nagoya University

Committee Memberships

Jan, 2019 - Present

理事, 日本性差医学会・医療学会
Jun, 2014 - Present

理事, 日本血管内治療学会
Apr, 2014 - Present

教育研修委員会委員長, 日本循環器学会
Apr, 2014 - Present

理事, 日本循環器学会
Apr, 2013 - Present

理事, 日本心臓血管内視鏡学会

Papers

237

Association of onset-season with characteristics and long-term outcomes in acute myocardial infarction patients: results from the Japanese registry of acute myocardial infarction diagnosed by universal definition (J-MINUET) substudy.

Taishi Okuno, Jiro Aoki, Kengo Tanabe, Koichi Nakao, Yukio Ozaki, Kazuo Kimura, Junya Ako, Teruo Noguchi, Satoshi Yasuda, Satoru Suwa, Kazuteru Fujimoto, Yasuharu Nakama, Takashi Morita, Wataru Shimizu, Yoshihiko Saito, Atsushi Hirohata, Yasuhiro Morita, Teruo Inoue, Atsunori Okamura, Toshiaki Mano, Kazuhito Hirata, Yoshisato Shibata, Mafumi Owa, Kenichi Tsujita, Hiroshi Funayama, Nobuaki Kokubu, Ken Kozuma, Shiro Uemura, Tetsuya Tobaru, Keijiro Saku, Shigeru Ohshima, Kunihiro Nishimura, Yoshihiro Miyamoto, Hisao Ogawa, Masaharu Ishihara

Heart and vessels, 34(12) 1899-1908, Dec, 2019 Peer-reviewed
Post-interventional adverse event risk by vascular access site among patients with acute coronary syndrome in Japan: observational analysis with a national registry J-PCI database.

Toshiharu Fujii, Yuji Ikari, Hideki Hashimoto, Kazushige Kadota, Tetsuya Amano, Shiro Uemura, Hiroaki Takashima, Masato Nakamura

Cardiovascular intervention and therapeutics, 34(4) 297-304, Oct, 2019 Peer-reviewed
Soluble CLEC-2 is generated independently of ADAM10 and is increased in plasma in acute coronary syndrome: comparison with soluble GPVI.

Osamu Inoue, Makoto Osada, Junya Nakamura, Fuminori Kazama, Toshiaki Shirai, Nagaharu Tsukiji, Tomoyuki Sasaki, Hiroshi Yokomichi, Tomotaka Dohi, Makoto Kaneko, Makoto Kurano, Mitsuru Oosawa, Shogo Tamura, Kaneo Satoh, Katsuhiro Takano, Katsumi Miyauchi, Hiroyuki Daida, Yutaka Yatomi, Yukio Ozaki, Katsue Suzuki-Inoue

International journal of hematology, 110(3) 285-294, Sep, 2019 Peer-reviewed
Computed Tomographic Angiography-Verified Myocardial Bridge and Invasive Angiography-Verified Left Anterior Descending Coronary Artery Vasospasm.

Kawai H, Ohta M, Motoyama S, Hashimoto Y, Takahashi H, Muramatsu T, Sarai M, Narula J, Ozaki Y

JACC. Cardiovascular interventions, 13(1) 144-146, Sep, 2019 Peer-reviewed
Relationship between coronary plaque morphology of the left anterior descending artery and 12 months clinical outcome: the CLIMA study.

Prati F, Romagnoli E, Gatto L, La Manna A, Burzotta F, Ozaki Y, Marco V, Boi A, Fineschi M, Fabbiocchi F, Taglieri N, Niccoli G, Trani C, Versaci F, Calligaris G, Ruscica G, Di Giorgio A, Vergallo R, Albertucci M, Biondi-Zoccai G, Tamburino C, Crea F, Alfonso F, Arbustini E, CLIMA Investigators

European heart journal, Aug, 2019 Peer-reviewed

Misc.

231

Associations of coronary plaque characteristics by integrated backscatter intravascular ultrasound with detectability of vessel external elastic lamina using optical frequency domain imaging in human coronary arteries: A sub-analysis of the MISTIC-1 trial.

Masato Ishikawa, Takashi Muramatsu, Mamoru Nanasato, Ryo Nagasaka, Hidemaro Takatsu, Yu Yoshiki, Yosuke Hashimoto, Masaya Ohota, Masanori Okumura, Hiroyuki Naruse, Junichi Ishii, Katsuyoshi Ito, Hiroshi Takahashi, Hiroki Kamiya, Yukihiko Yoshida, Yukio Ozaki

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 94(7) 947-955, Dec 1, 2019
Admission Heart Rate Is a Determinant of Effectiveness of Beta-Blockers in Acute Myocardial Infarction Patients.

Taishi Okuno, Jiro Aoki, Kengo Tanabe, Koichi Nakao, Yukio Ozaki, Kazuo Kimura, Junya Ako, Teruo Noguchi, Satoshi Yasuda, Satoru Suwa, Kazuteru Fujimoto, Yasuharu Nakama, Takashi Morita, Wataru Shimizu, Yoshihiko Saito, Atsushi Hirohata, Yasuhiro Morita, Teruo Inoue, Atsunori Okamura, Toshiaki Mano, Kazuhito Hirata, Yoshisato Shibata, Mafumi Owa, Kenichi Tsujita, Hiroshi Funayama, Nobuaki Kokubu, Ken Kozuma, Shiro Uemura, Tetsuya Tobaru, Keijiro Saku, Shigeru Ohshima, Kunihiro Nishimura, Yoshihiro Miyamoto, Hisao Ogawa, Masaharu Ishihara

Circulation journal : official journal of the Japanese Circulation Society, 83(5) 1054-1063, Apr 25, 2019
Frequency and prognostic impact of intravascular imaging-guided urgent percutaneous coronary intervention in patients with acute myocardial infarction: results from J-MINUET.

Hiroyuki Okura, Yoshihiko Saito, Tsunenari Soeda, Koichi Nakao, Yukio Ozaki, Kazuo Kimura, Junya Ako, Teruo Noguchi, Satoshi Yasuda, Satoru Suwa, Kazuteru Fujimoto, Yasuharu Nakama, Takashi Morita, Wataru Shimizu, Atsushi Hirohata, Yasuhiro Morita, Teruo Inoue, Atsunori Okamura, Masaaki Uematsu, Kazuhito Hirata, Kengo Tanabe, Yoshisato Shibata, Mafumi Owa, Kenichi Tsujita, Kunihiro Nishimura, Yoshihiro Miyamoto, Masaharu Ishihara

Heart and vessels, 34(4) 564-571, Apr, 2019
A Decision Tree-Based Survival Analysis of Patients with a History of Inappropriate Implantable Cardioverter-Defibrillator Therapy.

Masaru Yamamoto, Katsunori Okajima, Akira Shimane, Tomoya Ozawa, Itsuro Morishima, Toru Asai, Masahiko Takagi, Atsunobu Kasai, Eitaro Fujii, Ken Kiyono, Eiichi Watanabe, Yukio Ozaki

International heart journal, 60(2) 318-326, Mar 20, 2019
Comparison of Outcomes After Percutaneous Coronary Intervention in Elderly Patients, Including 10 628 Nonagenarians: Insights From a Japanese Nationwide Registry (J-PCI Registry).

Yohei Numasawa, Taku Inohara, Hideki Ishii, Kyohei Yamaji, Shun Kohsaka, Mitsuaki Sawano, Masaki Kodaira, Shiro Uemura, Kazushige Kadota, Tetsuya Amano, Masato Nakamura

Journal of the American Heart Association, 8(5) e011183, Mar 5, 2019
Impact of serum albumin levels on supratherapeutic PT-INR control and bleeding risk in atrial fibrillation patients on warfarin: A prospective cohort study.

Mayumi Kawai, Masahide Harada, Yuji Motoike, Masayuki Koshikawa, Tomohide Ichikawa, Eiichi Watanabe, Yukio Ozaki

International journal of cardiology. Heart & vasculature, 22 111-116, Mar, 2019
A multicenter trial of extracorporeal cardiac shock wave therapy for refractory angina pectoris: report of the highly advanced medical treatment in Japan.

Yoku Kikuchi, Kenta Ito, Tomohiko Shindo, Kiyotaka Hao, Takashi Shiroto, Yasuharu Matsumoto, Jun Takahashi, Takao Matsubara, Akira Yamada, Yukio Ozaki, Michiaki Hiroe, Kazuo Misumi, Hideki Ota, Kentaro Takanami, Tomomichi Hiraide, Kei Takase, Fumiya Tanji, Yasutake Tomata, Ichiro Tsuji, Hiroaki Shimokawa

Heart and vessels, 34(1) 104-113, Jan, 2019
Serum microRNA-126 and -223 as new-generation biomarkers for sarcoidosis in patients with heart failure.

Wakaya Fujiwara, Yasuchika Kato, Mutsuharu Hayashi, Yoshinori Sugishita, Satoshi Okumura, Masataka Yoshinaga, Tomoya Ishiguro, Ryo Yamada, Sayano Ueda, Masahide Harada, Hiroyuki Naruse, Junnichi Ishii, Yukio Ozaki, Hideo Izawa

Journal of cardiology, 72(6) 452-457, Dec, 2018
Electrocadiographic Scoring Helps Predict Left Ventricular Wall Motion Abnormality Commonly Observed after Subarachnoid Hemorrhage.

Keiko Sugimoto, Akira Yamada, Joji Inamasu, Yuichi Hirose, Kayoko Takada, Kunihiko Sugimoto, Risako Tanaka, Eiichi Watanabe, Yukio Ozaki

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 27(11) 3148-3154, Nov, 2018
Left Atrial Appendage Thrombus Prior to Atrial Fibrillation Ablation in the Era of Direct Oral Anticoagulants.

Masahide Harada, Masayuki Koshikawa, Yuji Motoike, Tomohide Ichikawa, Kunihiko Sugimoto, Eiichi Watanabe, Yukio Ozaki

Circulation journal : official journal of the Japanese Circulation Society, 82(11) 2715-2721, Oct 25, 2018
Pre-Procedural Thrombolysis in Myocardial Infarction Flow in Patients with ST-Segment Elevation Myocardial Infarction.

Takuya Hashimoto, Junya Ako, Koichi Nakao, Yukio Ozaki, Kazuo Kimura, Teruo Noguchi, Satoshi Yasuda, Satoru Suwa, Kazuteru Fujimoto, Yasuharu Nakama, Takashi Morita, Wataru Shimizu, Yoshihiko Saito, Atsushi Hirohata, Yasuhiro Morita, Teruo Inoue, Atsunori Okamura, Masaaki Uematsu, Kazuhito Hirata, Kengo Tanabe, Yoshisato Shibata, Mafumi Owa, Kenichi Tsujita, Hiroshi Funayama, Nobuaki Kokubu, Ken Kozuma, Shirou Uemura, Tetsuya Toubaru, Keijirou Saku, Shigeru Oshima, Michikazu Nakai, Kunihiro Nishimura, Yoshihiro Miyamoto, Hisao Ogawa, Masaharu Ishihara

International heart journal, 59(5) 920-925, Sep 26, 2018
Predicting acute kidney injury using urinary liver-type fatty-acid binding protein and serum N-terminal pro-B-type natriuretic peptide levels in patients treated at medical cardiac intensive care units.

Hiroyuki Naruse, Junnichi Ishii, Hiroshi Takahashi, Fumihiko Kitagawa, Hideto Nishimura, Hideki Kawai, Takashi Muramatsu, Masahide Harada, Akira Yamada, Sadako Motoyama, Shigeru Matsui, Mutsuharu Hayashi, Masayoshi Sarai, Eiichi Watanabe, Hideo Izawa, Yukio Ozaki

Critical care (London, England), 22(1) 197-197, Aug 18, 2018
Rationale and Design of the Multicenter Trial on Japan Working Group on the Effects of Angiotensin Receptor Blockers Selection (Azilsartan vs. Candesartan) on Diastolic Function in the Patients Suffering from Heart Failure with Preserved Ejection Fraction: J-TASTE Trial.

Hiroyuki Takahama, Masanori Asakura, Yukio Abe, Masayoshi Ajioka, Kazutaka Aonuma, Toshihisa Anzai, Takaharu Hayashi, Shinya Hiramitsu, Hiroya Kawai, Hidetaka Kioka, Kazuo Kimura, Young-Jae Lim, Ken Matsuoka, Hirohiko Motoki, Yoji Nagata, Sunao Nakamura, Nobuyuki Ohte, Yukio Ozaki, Taishi Sasaoka, Shunsuke Tamaki, Toshimitsu Hamasaki, Masafumi Kitakaze

Cardiovascular drugs and therapy, 32(4) 381-388, Aug, 2018
“Twin Icicle” Calcifications Cause Aortic Annular Rupture

Masato Tochii, Takashi Muramatsu, Kentaro Amano, Masato Ishikawa, Naoki Hoshino, Meiko Miyagi, Akira Yamada, Yoshiyuki Takami, Yukio Ozaki, Yasushi Takagi

Annals of Thoracic Surgery, 106, Aug 1, 2018
Clinical implication of LAVI over A′ ratio in patients with acute coronary syndrome

Hideaki Matsuura, Akira Yamada, Kunihiko Sugimoto, Keiko Sugimoto, Masatsugu Iwase, Takashi Ishikawa, Junichi Ishii, Yukio Ozaki

Heart Asia, 10, Jun 1, 2018
Prediction of Thrombotic and Bleeding Events After Percutaneous Coronary Intervention: CREDO-Kyoto Thrombotic and Bleeding Risk Scores.

Masahiro Natsuaki, Takeshi Morimoto, Kyohei Yamaji, Hirotoshi Watanabe, Yusuke Yoshikawa, Hiroki Shiomi, Yoshihisa Nakagawa, Yutaka Furukawa, Kazushige Kadota, Kenji Ando, Takashi Akasaka, Keiichi Igarashi Hanaoka, Ken Kozuma, Kengo Tanabe, Yoshihiro Morino, Toshiya Muramatsu, Takeshi Kimura

Journal of the American Heart Association, 7(11), May 22, 2018
High-Dose Versus Low-Dose Pitavastatin in Japanese Patients With Stable Coronary Artery Disease (REAL-CAD): A Randomized Superiority Trial.

Isao Taguchi, Satoshi Iimuro, Hiroshi Iwata, Hiroaki Takashima, Mitsuru Abe, Eisuke Amiya, Takanori Ogawa, Yukio Ozaki, Ichiro Sakuma, Yoshihisa Nakagawa, Kiyoshi Hibi, Takafumi Hiro, Yoshihiro Fukumoto, Seiji Hokimoto, Katsumi Miyauchi, Tsutomu Yamazaki, Hiroshi Ito, Yutaka Otsuji, Kazuo Kimura, Jun Takahashi, Atsushi Hirayama, Hiroyoshi Yokoi, Kazuo Kitagawa, Takao Urabe, Yasushi Okada, Yasuo Terayama, Kazunori Toyoda, Takehiko Nagao, Masayasu Matsumoto, Yasuo Ohashi, Tetsuji Kaneko, Retsu Fujita, Hiroshi Ohtsu, Hisao Ogawa, Hiroyuki Daida, Hiroaki Shimokawa, Yasushi Saito, Takeshi Kimura, Teruo Inoue, Masunori Matsuzaki, Ryozo Nagai

Circulation, 137(19) 1997-2009, May 8, 2018
A lower eicosapentaenoic acid/arachidonic acid ratio is associated with in-hospital fatal arrhythmic events in patients with acute myocardial infarction: a J-MINUET substudy

Takuya Hashimoto, Junya Ako, Koichi Nakao, Yukio Ozaki, Kazuo Kimura, Teruo Noguchi, Satoshi Yasuda, Satoru Suwa, Kazuteru Fujimoto, Yasuharu Nakama, Takashi Morita, Wataru Shimizu, Yoshihiko Saito, Atsushi Hirohata, Yasuhiro Morita, Teruo Inoue, Atsunori Okamura, Masaaki Uematsu, Kazuhito Hirata, Kengo Tanabe, Yoshisato Shibata, Mafumi Owa, Kenichi Tsujita, Hiroshi Funayama, Nobuaki Kokubu, Ken Kozuma, Shirou Uemura, Tetsuya Toubaru, Keijirou Saku, Shigeru Ohshima, Michikazu Nakai, Kunihiro Nishimura, Yoshihiro Miyamoto, Hisao Ogawa, Masaharu Ishihara, on behalf of J-MINUET investigators

Heart and Vessels, 33(5) 481-488, May 1, 2018
Recovery from anthracycline-induced cardiomyopathy with biventricular assist and valve repairs: A case report and literature review

Yoshiyuki Takami, Naoki Hoshino, Yasuchika Kato, Yusuke Sakurai, Kentaro Amano, Yoshiro Higuchi, Masato Tochii, Michiko Ishida, Hiroshi Ishikawa, Yasushi Takagi, Yukio Ozaki

International Journal of Artificial Organs, 41 413-417, May 1, 2018
Thromboembolisms in atrial fibrillation and heart failure patients with a preserved ejection fraction (HFpEF) compared to those with a reduced ejection fraction (HFrEF).

Yoshihiro Sobue, Eiichi Watanabe, Gregory Y H Lip, Masayuki Koshikawa, Tomohide Ichikawa, Mayumi Kawai, Masahide Harada, Joji Inamasu, Yukio Ozaki

Heart and vessels, 33(4) 403-412, Apr, 2018
Reply to the Letter to the Editors: "Takotsubo syndrome: Still a benign entity?"

Yoshihiro Sobue, Eiichi Watanabe, Tomohide Ichikawa, Yukio Ozaki

International journal of cardiology, 256 16-16, Apr 1, 2018
CVIT expert consensus document on primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) in 2018.

Yukio Ozaki, Yuki Katagiri, Yoshinobu Onuma, Tetsuya Amano, Takashi Muramatsu, Ken Kozuma, Satoru Otsuji, Takafumi Ueno, Nobuo Shiode, Kazuya Kawai, Nobuhiro Tanaka, Kinzo Ueda, Takashi Akasaka, Keiichi Igarashi Hanaoka, Shiro Uemura, Hirotaka Oda, Yoshiaki Katahira, Kazushige Kadota, Eisho Kyo, Katsuhiko Sato, Tadaya Sato, Junya Shite, Koichi Nakao, Masami Nishino, Yutaka Hikichi, Junko Honye, Tetsuo Matsubara, Sumio Mizuno, Toshiya Muramatsu, Taku Inohara, Shun Kohsaka, Ichiro Michishita, Hiroyoshi Yokoi, Patrick W Serruys, Yuji Ikari, Masato Nakamura

Cardiovascular intervention and therapeutics, 33(2) 178-203, Apr, 2018
Rationale and Design of Randomized Evaluation of Aggressive or Moderate Lipid Lowering Therapy with Pitavastatin in Coronary Artery Disease (REAL-CAD) Trial.

Katsumi Miyauchi, Takeshi Kimura, Hiroaki Shimokawa, Hiroyuki Daida, Satoshi Iimuro, Hiroshi Iwata, Yukio Ozaki, Ichiro Sakuma, Yoshihisa Nakagawa, Kiyoshi Hibi, Takafumi Hiro, Yoshihiro Fukumoto, Seiji Hokimoto, Yasuo Ohashi, Hiroshi Ohtsu, Yasushi Saito, Masunori Matsuzaki, Ryozo Nagai

International heart journal, 59(2) 315-320, Mar 30, 2018
In vitro validation of coronary CT angiography for the evaluation of complex lesions

Carlos Collet, Yoshinobu Onuma, Maik J. Grundeken, Yosuke Miyazaki, Marcio Bittercourt, Pieter Kitslaar, Sadako Motoyama, Yukio Ozaki, Taku Asano, Jolanda J. Wentzel, Geert J. Streekstra, Patrick W. Serruys, Robbert J. De Winter, R. Nils Planken

EuroIntervention, 13(15) e1823-e1830, Feb 1, 2018
Rivaroxaban with or without aspirin in patients with stable coronary artery disease: an international, randomised, double-blind, placebo-controlled trial

Stuart J. Connolly, John W. Eikelboom, Jackie Bosch, Gilles Dagenais, Leanne Dyal, Fernando Lanas, Kaj Metsarinne, Martin O'Donnell, Anthony L. Dans, Jong Won Ha, Alexandr N. Parkhomenko, Alvaro A. Avezum, Eva Lonn, Liu Lisheng, Christian Torp-Pedersen, Petr Widimsky, Aldo P. Maggioni, Camilo Felix, Katalin Keltai, Masatsugu Hori, Khalid Yusoff, Tomasz J. Guzik, Deepak L. Bhatt, Kelley R.H. Branch, Nancy Cook Bruns, Scott D. Berkowitz, Sonia S. Anand, John D. Varigos, Keith A.A. Fox, Salim Yusuf, JORGELINA SALA, L. U.I.S. CARTASEGNA, MARISA VICO, MIGUEL ANGEL, HOMINAL, EDUARDO HASBANI, ALBERTO CACCAVO, CESAR ZAIDMAN, DANIEL VOGEL, ADRIAN HRABAR, PABLO OMAR SCHYGIEL, CARLOS CUNEO, H. U.G.O. LUQUEZ, IGNACIO J, MACKINNON, RODOLFO ANDRES AHUAD GUERRERO, JUAN PABLO COSTABEL, INES PALMIRA BARTOLACCI, OSCAR MONTANA, MARIA BARBIERI, OSCAR GOMEZ VILAMAJO, RUBEN OMAR, GARCIA DURAN, LILIA BEATRIZ SCHIAVI, MARCELO GARRIDO, ADRIAN INGARAMO, ANSELMO PAULINO BORDONAVA, MARIA JOSE PELAGAGGE, LEONARDO NOVARETTO, JUAN PABLO ALBISU, DI GENNERO, LUZ MARIA IBANEZ SAGGIA, MOIRA ALVAREZ, NESTOR ALEJANDRO VITA, STELLA MARIS MACIN, RICARDO DARIO DRAN, MARCELO CARDONA, L. U.I.S. GUZMAN, RODOLFO JUAN, SARJANOVICH, JESUS CUADRADO, SEBASTIAN NANI, MARCOS RAUL, LITVAK BRUNO, CAROLINA CHACON, LAURA ELENA MAFFEI, DIEGO GRINFELD, NATALIA VENSENTINI, CLAUDIO RODOLFO MAJUL, HECTOR LUCAS LUCIARDI, PATRICIA DEL CARMEN, GONZALEZ COLASO, FREDY ANTONI, FERRE PACORA, P. A.U.L. VAN, DEN HEUVEL, PETER VERHAMME, B. A.V.O. ECTOR, PHILIPPE DEBONNAIRE, PHILIPPE VAN, DE BORNE, J. E.A.N. LEROY, HERMAN SCHROE, PASCAL VRANCKX, I. V.A.N. ELEGEERT, ETIENNE HOFFER, K. A.R.L, DUJARDIN, CLARISSE INDIO DO BRASIL, DALTON PRECOMA, JOSE ANTONIO ABRANTES, EULER MANENTI, GILMAR REIS, J. O.S.E. SARAIVA, LILIA MAIA, MAURO HERNANDES, PAULO ROSSI, FABIO ROSSI DOS SANTOS, SERGIO LUIZ, ZIMMERMANN, RAFAEL RECH, EDUARDO ABIB

The Lancet, 391 205-218, Jan 20, 2018
Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial

Sonia S. Anand, Jackie Bosch, John W. Eikelboom, Stuart J. Connolly, Rafael Diaz, Peter Widimsky, Victor Aboyans, Marco Alings, Ajay K. Kakkar, Katalin Keltai, Aldo P. Maggioni, Basil S. Lewis, Stefan Störk, Jun Zhu, Patricio Lopez-Jaramillo, Martin O'Donnell, Patrick J. Commerford, Dragos Vinereanu, Nana Pogosova, Lars Ryden, Keith A.A. Fox, Deepak L. Bhatt, Frank Misselwitz, John, D. Varigos, Thomas Vanassche, Alvaro A. Avezum, Edmond Chen, Kelley Branch, Darryl P. Leong, Shrikant I. Bangdiwala, Robert G. Hart, Salim Yusuf, JORGELINA SALA, L. U.I.S. CARTASEGNA, MARISA VICO, MIGUEL ANGEL, HOMINAL, EDUARDO HASBANI, ALBERTO CACCAVO, CESAR ZAIDMAN, DANIEL VOGEL, ADRIAN HRABAR, PABLO OMAR SCHYGIEL, CARLOS CUNEO, H. U.G.O. LUQUEZ, IGNACIO J, MACKINNON, RODOLFO ANDRES AHUAD GUERRERO, JUAN PABLO COSTABEL, INES PALMIRA BARTOLACCI, OSCAR MONTANA, MARIA BARBIERI, OSCAR GOMEZ VILAMAJO, RUBEN OMAR, GARCIA DURAN, LILIA BEATRIZ SCHIAVI, MARCELO GARRIDO, ADRIAN INGARAMO, ANSELMO PAULINO BORDONAVA, MARIA JOSE PELAGAGGE, LEONARDO NOVARETTO, JUAN PABLO ALBISU, DI GENNERO, LUZ MARIA IBANEZ SAGGIA, MOIRA ALVAREZ, NESTOR ALEJANDRO VITA, STELLA MARIS MACIN, RICARDO DARIO DRAN, MARCELO CARDONA, L. U.I.S. GUZMAN, RODOLFO JUAN, SARJANOVICH, JESUS CUADRADO, SEBASTIAN NANI, MARCOS RAUL, LITVAK BRUNO, CAROLINA CHACON, LAURA ELENA MAFFEI, DIEGO GRINFELD, NATALIA VENSENTINI, CLAUDIO RODOLFO MAJUL, HECTOR LUCAS LUCIARDI, PATRICIA DEL CARMEN, GONZALEZ COLASO, FREDY ANTONI, FERRE PACORA, P. A.U.L. VAN, DEN HEUVEL, PETER VERHAMME, B. A.V.O. ECTOR, PHILIPPE DEBONNAIRE, PHILIPPE VAN, DE BORNE, J. E.A.N. LEROY, HERMAN SCHROE, PASCAL VRANCKX, I. V.A.N. ELEGEERT, ETIENNE HOFFER, K. A.R.L, DUJARDIN, CLARISSE INDIO DO BRASIL, DALTON PRECOMA, JOSE ANTONIO ABRANTES, EULER MANENTI, GILMAR REIS, J. O.S.E. SARAIVA, LILIA MAIA, MAURO HERNANDES, PAULO ROSSI, FABIO ROSSI DOS SANTOS, SERGIO LUIZ, ZIMMERMANN

The Lancet, 391 219-229, Jan 20, 2018
Imaging assessment of bioresorbable vascular scaffolds

Yohei Sotomi, Pannipa Suwannasom, Erhan Tenekecioglu, Carlos Collet, Shimpei Nakatani, Takayuki Okamura, Takashi Muramatsu, Yuki Ishibashi, Hiroki Tateishi, Yosuke Miyazaki, Taku Asano, Yuki Katagiri, Constantin von zur Muehlen, Kengo Tanabe, Ken Kozuma, Yukio Ozaki, Patrick W. Serruys, Yoshinobu Onuma

Cardiovascular Intervention and Therapeutics, 33(1) 11-22, Jan 1, 2018
Time trend in interest and satisfaction towards clinical training and academic activities among early-career cardiologists: The Japanese circulation society post-graduate training survey

Takashi Kohno, Shun Kohsaka, Yasuyoshi Takei, Keiichi Fukuda, Yukio Ozaki, Akira Yamashina

Circulation Journal, 82(2) 423-429, 2018
Early prediction model for successful bridge to recovery in patients with fulminant myocarditis supported with percutaneous venoarterial extracorporeal membrane oxygenation ― Insights from the change pump study ―

Akinori Sawamura, Takahiro Okumura, Akihiro Hirakawa, Masaaki Ito, Yukio Ozaki, Nobuyuki Ohte, Tetsuya Amano, Toyoaki Murohara, The CHANGE PUMP Investigators

Circulation Journal, 82(3) 699-707, 2018
Effects of ezetimibe-statin combination therapy on coronary atherosclerosis in acute coronary syndrome

Kiyoshi Hibi, Shinjo Sonoda, Masanori Kawasaki, Yutaka Otsuji, Toyoaki Murohara, Hideki Ishii, Katsuhiko Sato, Ryoji Koshida, Yukio Ozaki, Masataka Sata, Yoshihiro Morino, Tadashi Miyamoto, Tetsuya Amano, Satoshi Morita, Ken Kozuma, Kazuo Kimura, Hisayoshi Fujiwara, Ezetimibe-ACS Investigators

Circulation Journal, 82(3) 757-766, 2018
A high level of blood urea nitrogen is a significant predictor for in-hospital mortality in patients with acute myocardial infarction

Yu Horiuchi, Jiro Aoki, Kengo Tanabe, Koichi Nakao, Yukio Ozaki, Kazuo Kimura, Junya Ako, Satoshi Yasuda, Teruo Noguchi, Satoru Suwa, Kazuteru Fujimoto, Yasuharu Nakama, Takashi Morita, Wataru Shimizu, Yoshihiko Saito, Atsushi Hirohata, Yasuhiro Morita, Teruo Inoue, Atsunori Okamura, Masaaki Uematsu, Kazuhito Hirata, Yoshisato Shibata, Michikazu Nakai, Kunihiro Nishimura, Yoshihiro Miyamoto, Masaharu Ishihara, J-MINUET investigators

International Heart Journal, 59(2) 263-271, 2018
Ultra-high-resolution computed tomography angiography for assessment of coronary artery stenosis

Sadako Motoyama, Hajime Ito, Masayoshi Sarai, Yasuomi Nagahara, Keiichi Miyajima, Ryota Matsumoto, Yujiro Doi, Yumi Kataoka, Hiroshi Takahashi, Yukio Ozaki, Hiroshi Toyama, Kazuhiro Katada

Circulation Journal, 82(7) 1844-1851, 2018
Prognostic value of electrocardiography in patients with fulminant myocarditis supported by percutaneous venoarterial extracorporeal membrane oxygenation ― Analysis from the change pump study ―

Akinori Sawamura, Takahiro Okumura, Masaaki Ito, Yukio Ozaki, Nobuyuki Ohte, Tetsuya Amano, Toyoaki Murohara

Circulation Journal, 82(8) 2089-2095, Jan 1, 2018
Noninvasive assessment of stenotic severity and plaque characteristics by coronary CT angiography in patients scheduled for carotid artery revascularization

Meiko Hoshino, Hideki Kawai, Masayoshi Sarai, Akiyo Sadato, Motoharu Hayakawa, Sadako Motoyama, Yasuomi Nagahara, Keiichi Miyajima, Hiroshi Takahashi, Junnichi Ishii, Ichiro Nakahara, Yuichi Hirose, Yukio Ozaki

Journal of Atherosclerosis and Thrombosis, 25(10) 1022-1031, Jan 1, 2018
Off-hours presentation does not affect in-hospital mortality of Japanese patients with acute myocardial infarction: J-MINUET substudy

Manabu Ogita, Satoru Suwa, Hideki Ebina, Koichi Nakao, Yukio Ozaki, Kazuo Kimura, Junya Ako, Teruo Noguchi, Satoshi Yasuda, Kazuteru Fujimoto, Yasuharu Nakama, Takashi Morita, Wataru Shimizu, Yoshihiko Saito, Atsushi Hirohata, Yasuhiro Morita, Teruo Inoue, Atsunori Okamura, Masaaki Uematsu, Kazuhito Hirata, Kengo Tanabe, Yoshisato Shibata, Mafumi Owa, Seiji Hokimoto, Hiroshi Funayama, Nobuaki Kokubu, Ken Kozuma, Shiro Uemura, Tetsuya Toubaru, Keijiro Saku, Shigeru Oshima, Kunihiro Nishimura, Yoshihiro Miyamoto, Masaharu Ishihara

JOURNAL OF CARDIOLOGY, 70(5-6) 553-558, Nov, 2017
Prognostic Value of Combination of Plasma D-Dimer Concentration and Estimated Glomerular Filtration Rate in Predicting Long-Term Mortality of Patients With Stable Coronary Artery Disease

Hiroyuki Naruse, Junnichi Ishii, Hiroshi Takahashi, Fumihiko Kitagawa, Ryuunosuke Okuyama, Hideki Kawai, Takashi Muramatsu, Masahide Harada, Akira Yamada, Sadako Motoyama, Shigeru Matsui, Mutsuharu Hayashi, Masayoshi Sarai, Eiichi Watanabe, Hideo Izawa, Yukio Ozaki

CIRCULATION JOURNAL, 81(10) 1506-1513, Oct, 2017
Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease

J. W. Eikelboom, S. J. Connolly, J. Bosch, G. R. Dagenais, R. G. Hart, O. Shestakovska, R. Diaz, M. Alings, E. M. Lonn, S. S. Anand, P. Widimsky, M. Hori, A. Avezum, L. S. Piegas, K. R. H. Branch, J. Probstfield, D. L. Bhatt, J. Zhu, Y. Liang, A. P. Maggioni, P. Lopez-Jaramillo, M. O'Donnell, A. K. Kakkar, K. A. A. Fox, A. N. Parkhomenko, G. Ertl, S. Stoerk, M. Keltai, L. Ryden, N. Pogosova, A. L. Dans, F. Lanas, P. J. Commerford, C. Torp-Pedersen, T. J. Guzik, P. B. Verhamme, D. Vinereanu, J. -H. Kim, A. M. Tonkin, B. S. Lewis, C. Felix, K. Yusoff, P. G. Steg, K. P. Metsarinne, N. Cook Bruns, F. Misselwitz, E. Chen, D. Leong, S. Yusuf

NEW ENGLAND JOURNAL OF MEDICINE, 377(14) 1319-1330, Oct, 2017
Reply to “Physically triggered takotsubo cardiomyopathy has a worse prognosis: Potential roles of systemic inflammation and coronary slow flow phenomenon”

Yoshihiro Sobue, Eiichi Watanabe, Tomohide Ichikawa, Yukio Ozaki

International Journal of Cardiology, 242 30, Sep 1, 2017
Long-Term Outcomes of Non-ST-Elevation Myocardial Infarction Without Creatine Kinase Elevation - The J-MINUET Study -

Masaharu Ishihara, Koichi Nakao, Yukio Ozaki, Kazuo Kimura, Junya Ako, Teruo Noguchi, Masashi Fujino, Satoshi Yasuda, Satoru Suwa, Kazuteru Fujimoto, Yasuharu Nakama, Takashi Morita, Wataru Shimizu, Yoshihiko Saito, Atsushi Hirohata, Yasuhiro Morita, Teruo Inoue, Atsunori Okamura, Masaaki Uematsu, Kazuhito Hirata, Kengo Tanabe, Yoshisato Shibata, Mafumi Owa, Kenichi Tsujita, Hiroshi Funayama, Nobuaki Kokubu, Ken Kozuma, Tetsuya Tobaru, Shigeru Oshima, Michikazu Nakai, Kunihiro Nishimura, Yoshihiro Miyamoto, Hisao Ogawa

CIRCULATION JOURNAL, 81(7) 958-+, Jul, 2017
Assessment of endothelial shear stress in patients with mild or intermediate coronary stenoses using coronary computed tomography angiography: comparison with invasive coronary angiography

Dexiao Huang, Takashi Muramatsu, Yingguang Li, Wenjie Yang, Yasuomi Nagahara, Miao Chu, Pieter Kitslaar, Masayoshi Sarai, Yukio Ozaki, Yiannis S. Chatzizisis, Fuhua Yan, Johan H. C. Reiber, Renhua Wu, Jun Pu, Shengxian Tu

INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, 33(7) 1101-1110, Jul, 2017
Impact of symptom presentation on in-hospital outcomes in patients with acute myocardial infarction

Masashi Fujino, Masaharu Ishihara, Hisao Ogawa, Koichi Nakao, Satoshi Yasuda, Teruo Noguchi, Yukio Ozaki, Kazuo Kimura, Satoru Suwa, Kazuteru Fujimoto, Yasuharu Nakama, Takashi Morita, Wataru Shimizu, Yoshihiko Saito, Atsushi Hirohata, Yasuhiro Morita, Teruo Inoue, Atsunori Okamura, Masaaki Uematsu, Junya Ako, Michikazu Nakai, Kunihiro Nishimura, Yoshihiro Miyamoto

JOURNAL OF CARDIOLOGY, 70(1-2) 29-34, Jul, 2017
Combination of high-sensitivity troponin I and N-terminal pro-B-type natriuretic peptide predicts future hospital admission for heart failure in high-risk hypertensive patients with preserved left ventricular ejection fraction

Ryunosuke Okuyama, Junnichi Ishii, Hiroshi Takahashi, Hideki Kawai, Takashi Muramatsu, Masahide Harada, Akira Yamada, Sadako Motoyama, Shigeru Matsui, Hiroyuki Naruse, Masayoshi Sarai, Midori Hasegawa, Eiichi Watanabe, Atsushi Suzuki, Mutsuharu Hayashi, Hideo Izawa, Yukio Yuzawa, Yukio Ozaki

HEART AND VESSELS, 32(7) 880-892, Jul, 2017
Dual Antiplatelet Therapy for 6 Versus 18 Months After Biodegradable Polymer Drug-Eluting Stent Implantation

Masato Nakamura, Raisuke Iijima, Junya Ako, Toshiro Shinke, Hisayuki Okada, Yoshiaki Ito, Kenji Ando, Hitoshi Anzai, Hiroyuki Tanaka, Yasunori Ueda, Shin Takiuchi, Yasunori Nishida, Hiroshi Ohira, Katsuhiro Kawaguchi, Makoto Kadotani, Hiroyuki Niinuma, Kazuto Omiya, Takashi Morita, Kan Zen, Yoshinori Yasaka, Kenji Inoue, Sugao Ishiwata, Masahiko Ochiai, Toshimitsu Hamasaki, Hiroyoshi Yokoi

JACC-CARDIOVASCULAR INTERVENTIONS, 10(12) 1189-1198, Jun, 2017
Impact of Acute Kidney Injury on In-Hospital Outcomes of Patients With Acute Myocardial Infarction - Results From the Japanese Registry of Acute Myocardial Infarction Diagnosed by Universal Definition (J-MINUET) Substudy -

Shotaro Kuji, Masami Kosuge, Kazuo Kimura, Koichi Nakao, Yukio Ozaki, Junya Ako, Teruo Noguchi, Satoshi Yasuda, Satoru Suwa, Kazuteru Fujimoto, Yasuharu Nakama, Takashi Morita, Wataru Shimizu, Yoshihiko Saito, Atsushi Hirohata, Yasuhiro Morita, Teruo Inoue, Kunihiro Nishimura, Yoshihiro Miyamoto, Masaharu Ishihara

CIRCULATION JOURNAL, 81(5) 733-739, May, 2017
Assessment of trough rivaroxaban concentrations on markers of coagulation activation in nonvalvular atrial fibrillation population

Fumihiko Kitagawa, Junnichi Ishii, Shinya Hiramitsu, Hiroshi Takahashi, Ryuunosuke Okuyama, Hideki Kawai, Takashi Muramatsu, Masahide Harada, Sadako Motoyama, Hiroyuki Naruse, Shigeru Matsui, Masayoshi Sarai, Mutsuharu Hayashi, Eiichi Watanabe, Hideo Izawa, Yukio Ozaki

HEART AND VESSELS, 32(5) 609-617, May, 2017
Impact of Institutional and Operator Volume on Short-Term Outcomes of Percutaneous Coronary Intervention A Report From the Japanese Nationwide Registry

Taku Inohara, Shun Kohsaka, Kyohei Yamaji, Tetsuya Amano, Kenshi Fujii, Hirotaka Oda, Shiro Uemura, Kazushige Kadota, Hiroaki Miyata, Masato Nakamura

JACC-CARDIOVASCULAR INTERVENTIONS, 10(9) 918-927, May, 2017
Physically triggered Takotsubo cardiomyopathy has a higher in-hospital mortality rate

Yoshihiro Sobue, Eiichi Watanabe, Tomohide Ichikawa, Masayuki Koshikawa, Mayumi Yamamoto, Masahide Harada, Yukio Ozaki

INTERNATIONAL JOURNAL OF CARDIOLOGY, 235 87-93, May, 2017
Brain natriuretic peptide as a potential novel marker of salt-sensitivity in chronic kidney disease patients without cardiac dysfunction

Mutsuharu Hayashi, Yoshinari Yasuda, Susumu Suzuki, Manaka Tagaya, Takehiro Ito, Tomohito Kamada, Masataka Yoshinaga, Yoshinori Sugishita, Wakaya Fujiwara, Hiroatsu Yokoi, Yukio Ozaki, Hideo Izawa

HEART AND VESSELS, 32(3) 279-286, Mar, 2017
Anatomic Myocardial Volume Index by CT Versus Physiological Index by FFR Angiography Between the Main Vessel and Side Branch

Yukio Ozaki

JACC-CARDIOVASCULAR INTERVENTIONS, 10(6) 582-584, Mar, 2017
Prognostic Importance of Novel Oxygen Desaturation Metrics in Patients With Heart Failure and Central Sleep Apnea

Eiichi Watanabe, Ken Kimono, Shojiro Matsui, Virend K. Somers, Kan Sano, Junichiro Hayano, Tomohide Ichikawa, Mayumi Kawai, Masahide Harada, Yukio Ozaki

JOURNAL OF CARDIAC FAILURE, 23(2) 131-137, Feb, 2017

Books and Other Publications

循環器疾患第2版

山科章, 近森大志郎

日本医事新報社, 2013
CVIT専門医試験準拠インターベンション必携

専門医認定医制度審議会手引書制作委員会

日本インターベンション治療学会, 2013
循環器疾患最新の治療2012-2013

堀正二, 永井良三

南江堂, 2012
今日の循環器疾患治療指針第3版

井上博, 許俊鋭, 檜垣實男, 代田浩之, 筒井裕之

医学書院, 2012
CT冠動脈造影実践学

木原康樹, 栗林幸夫

中外医学社, 2010

Presentations

354

心臓植込みデバイスの睡眠呼吸障害指標（ApneaScan）の変動

山本賢, 越川真行, 市川智英, 山本真由美, 祖父江嘉洋, 奥田健太郎, 藤原麻未, 辻川圭亮, 渡邉英一, 尾崎行男

第6回植込みデバイス関連冬季大会, 2014
Long Term Follow Up of the Patients with or without High Risk Plaque Detected by Coronary Computed Tomography Angiography

Ito H, Motoyama S, Sarai M, Kawai H, Nagahara Y, Harigaya H, Kan S, Naruse H, Ishii J, Ozaki Y

第78回日本循環器学会, 2014
Evaluation of Right Ventricular Hemodynamics by Two-dimensional Speckle Tracking in Patients with Chronic Pulmonary Thromboembolism

Shiino K, Sugimoto K, Yamada A, Inuzuka H, Kato M, Sone M, Takada K, Sugimoto K, Takagi Y, Iwase M, Ozaki Y

第78回日本循環器学会, 2014
Impact of Mild Increase in Serum Creatinine Levels in Patients Undergoing Emergency Coronary Intervention for Acute Coronary Syndrome (ACS)

Naruse H, Ishii J, Okuyama R, Ohta M, Hashimoto T, Hattori K, Okumura M, Mori Y, Matsui S, Izawa H, Ozaki Y

第78回日本循環器学会, 2014
Diagnostic Performance of Computed Tomography Perfusion in Coronary Artery Disease

Ito H, Motoyama S, Sarai M, Kawai H, Nagahara Y, Takada K, Okumura M, Naruse H, Ishii J, Ozaki Y

第78回日本循環器学会, 2014

Professional Memberships

Research Projects

マイクロRNAを利用した新規心不全診断ツールの開発

基盤研究(C), 文部科学省, Apr, 2016 - Mar, 2019

井澤英夫
薬物負荷造影心筋血流CTによる定量的心筋血流量評価

基盤研究(C), 文部科学省, Apr, 2016 - Mar, 2019

皿井正義
血清マイクロRNAプロファイリングによる新たな心房細動の臨床病態評価法の確立

基盤研究(C), 文部科学省, Apr, 2016 - Mar, 2019

原田将英
高精細冠動脈CTによるプラーク性状およびCT-FFRと侵襲的イメージングとの比較

基盤研究(C), 文部科学省, Apr, 2016 - Mar, 2019

尾崎行男
心不全をターゲットとしたバイオマーカーへのマイクロＲＮＡの応用

基盤研究(C), 文部科学省, Apr, 2013 - Mar, 2016

井澤英夫

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