yoshihara daisuke

(吉原大輔)

Profile Information

Affiliation: Education and Research Center of Animal Models for Human Diseases, Fujita Health University

Degree: 博士(医学）

J-GLOBAL ID: 201501016093988795
researchmap Member ID: 7000013073

Misc.

Telmisartan Ameliorates Fibrocystic Liver Disease in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease

Daisuke Yoshihara, Masanori Kugita, Mai Sasaki, Shigeo Horie, Koichi Nakanishi, Takaaki Abe, Harold M. Aukema, Tamio Yamaguchi, Shizuko Nagao

PLOS ONE, 8(12) 81480, Dec, 2013
Structure and Function of the Pancreas in the Polycystic Kidney Rat

Lanjuan Yi, Satoru Naruse, Sonoko Furuya, Akiko Yamamoto, Miyuki Nakakuki, Shizuko Nagao, Daisuke Yoshihara, Shigeru B. H. Ko, Muxin Wei, Takaharu Kondo, Hiroshi Ishiguro

PANCREAS, 41(8) 1292-1298, Nov, 2012
Global Gene Expression Profiling in PPAR-gamma Agonist-Treated Kidneys in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease

Daisuke Yoshihara, Masanori Kugita, Tamio Yamaguchi, Harold M. Aukema, Hiroki Kurahashi, Miwa Morita, Yoshiyuki Hiki, James P. Calvet, Darren P. Wallace, Takafumi Toyohara, Takaaki Abe, Shizuko Nagao

PPAR RESEARCH, 2012 695898-695907, 2012
Animal models for human polycystic kidney disease

Shizuko Nagao, Masanori Kugita, Daisuke Yoshihara, Tamio Yamaguchi

Experimental Animals, 61(5) 477-488, 2012
The Raf kinase inhibitor PLX5568 slows cyst proliferation in rat polycystic kidney disease but promotes renal and hepatic fibrosis

Bjoern Buchholz, Bernd Klanke, Gunnar Schley, Gideon Bollag, James Tsai, Sven Kroening, Daisuke Yoshihara, Darren P. Wallace, Bettina Kraenzlin, Norbert Gretz, Peter Hirth, Kai-Uwe Eckardt, Wanja M. Bernhardt

NEPHROLOGY DIALYSIS TRANSPLANTATION, 26(11) 3458-3465, Nov, 2011
Metabolomic profiling of the autosomal dominant polycystic kidney disease rat model

Takafumi Toyohara, Takehiro Suzuki, Yasutoshi Akiyama, Daisuke Yoshihara, Yoichi Takeuchi, Eikan Mishima, Koichi Kikuchi, Chitose Suzuki, Masayuki Tanemoto, Sadayoshi Ito, Shizuko Nagao, Tomoyoshi Soga, Takaaki Abe

CLINICAL AND EXPERIMENTAL NEPHROLOGY, 15(5) 676-687, Oct, 2011
PPAR-gamma agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease

Daisuke Yoshihara, Hiroki Kurahashi, Miwa Morita, Masanori Kugita, Yoshiyuki Hiki, Harold M. Aukema, Tamio Yamaguchi, James P. Calvet, Darren P. Wallace, Shizuko Nagao

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 300(2) F465-F474, Feb, 2011
Global gene expression profiling in early-stage polycystic kidney disease in the Han:SPRD Cy rat identifies a role for RXR signaling

Masanori Kugita, Kazuhiro Nishii, Miwa Morita, Daisuke Yoshihara, Hiroe Kowa-Sugiyama, Kouji Yamada, Tamio Yamaguchi, Darren P. Wallace, James P. Calvet, Hiroki Kurahashi, Shizuko Nagao

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 300(1) F177-F188, Jan, 2011
Polycystic kidney disease in Han:SPRD Cy rats is associated with elevated expression and mislocalization of SamCystin

Shizuko Nagao, Miwa Morita, Masanori Kugita, Daisuke Yoshihara, Tamio Yamaguchi, Hiroki Kurahashi, James P. Calvet, Darren P. Wallace

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 299(5) F1078-F1086, Nov, 2010

Books and Other Publications

小児外科

2014
『Annual Review 腎臓2013』

冨野康日己, 柏原直樹, 成田一衛

Presentations

多発性嚢胞腎症モデル動物Cyラットの腎臓におけるRXRの解析

釘田雅則, 佐々木麻衣, 吉原大輔, 長尾静子

第61回日本実験動物学会総会, 2014
ヒト多発性嚢胞腎症モデル動物の有用性と必要性

長尾静子, 釘田雅則, 吉原大輔, 山口太美雄

第60回日本実験動物学会総会, 2013
テルミサルタンによるヒト常染色体劣性多発性嚢胞腎症オーソログ遺伝子変異モデルにおける病態発現抑制効果

長尾静子, 枝澄香, 吉原大輔, 釘田雅則, 佐々木麻衣, 堀江重郎, 中西浩一, 阿部高明, 山口太美雄

第48回日本小児腎臓病学会学術集会, 2013
適切な疾患モデル動物に関する考察 ―多発性嚢胞腎症モデル動物を例としてー

長尾静子, 釘田雅則, 吉原大輔, 佐々木麻衣

第83回東海実験動物研究会, 2013
多発性嚢胞腎症における核内受容体Retinoid X Receptorの発現増加と細胞内局在の変化

佐々木麻衣, 釘田雅則, 吉原大輔, 長尾静子

第8回日本臨床検査学教育学会学術大会, 2013

その他教育活動上特記すべき事項

件名（英語）

-

終了年月日（英語）

2012/03/27

概要（英語）

動物実験に関わる法律関係講演と実験動物の基本的取扱い実習名古屋女子大学

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