伊藤祥輔

イトウショウスケ (Shosuke Ito)

基本情報

所属: 藤田医科大学メラニン化学研究所名誉教授

学位: 理学博士
医学博士

J-GLOBAL ID: 200901053326272218
researchmap会員ID: 1000102729

研究キーワード

研究分野

学歴

委員歴

1993年 - 2002年

国際色素細胞学会 International Federation of Pigment Cell Societies 事務局長,理事長
1987年

日本色素細胞学会理事

受賞

2020年11月

清寺眞記念賞リディアオリリー記念ピアス皮膚科学振興財団
2017年8月

Seiji Memorial Lecturer International Federation of Pigment Cell Societies (IFPCS)
2005年

The Henry Stanley Raper Medal (from European Society for Pigment Cell Research)
2002年

Honorary Member of the European Pigment Cell Society
1999年

Myron Gordon Award (国際色素細胞学会賞)

論文

250

A Cell-Based Evaluation of the Tyrosinase-Mediated Metabolic Activation of Leukoderma-Inducing Phenols, II: The Depletion of Nrf2 Augments the Cytotoxic Effect Evoked by Tyrosinase in Melanogenic Cells

Tomoko Nishimaki-Mogami, Shosuke Ito, Kazumasa Wakamatsu, Takumi Akiyama, Norimasa Tamehiro, Norihito Shibata

Biomolecules 2025年1月13日
メラノジェネシス標的低分子NPrCAPとナノマグネタイト粒子結合による次世代型低侵襲性メラノーマ化学・温熱・免疫療法(CTI療法)の産学共同開発

神保孝一, 肥田時征, 川上聡経, 伊藤祥輔, 若松一雅, 井藤彰, 本多裕之, 田村保明, 鳥越俊彦

日本皮膚科学会雑誌 134(12) 3017-3034 2024年11月
Pterostilbene, a Dimethyl Derivative of Resveratrol, Exerts Cytotoxic Effects on Melanin-Producing Cells through Metabolic Activation by Tyrosinase

Hitomi Tanaka, Tomoko Nishimaki-Mogami, Norimasa Tamehiro, Norihito Shibata, Hiroki Mandai, Shosuke Ito, Kazumasa Wakamatsu

International Journal of Molecular Sciences 2024年9月17日
Sperm Size Decreases With Increasing Pheomelanin Pigmentation but Not With the Amount of Glutathione in the Barn Swallow

Masaru Hasegawa, Emi Arai, Hitomi Tanaka, Shosuke Ito, Kazumasa Wakamatsu

Zoological Science 41(5) 2024年7月11日
Genetic insights into Tietz albinism‐deafness syndrome: A new dominant‐negative mutation in MITF

Kohei Yamamoto, Ken Okamura, Kazumasa Wakamatsu, Shosuke Ito, Kozue Akabane, Yosuke Arai, Junnosuke Kawaguchi, Yutaka Hozumi, Tamio Suzuki

Pigment Cell & Melanoma Research 2024年7月

もっとみる

MISC

210

Synthesis and selective in vitro anti-melanoma effect of enantiomeric alpha-methyl- and alpha-ethyl-4-S-cysteaminylphenol

J Yukitake, H Otake, S Inoue, K Wakamatsu, C Olivares, F Solano, K Hasegawa, S Ito

MELANOMA RESEARCH 13(6) 603-609 2003年12月
Quantitative analysis of eumelanin and pheomelanin in humans, mice, and other animals: A comparative review

S Ito, K Wakamatsu

PIGMENT CELL RESEARCH 16(5) 523-531 2003年10月
Cutaneous photobiology. The melanocyte vs. the sun: Who will win the final round?

AL Kadekaro, RJ Kavanagh, K Wakamatsu, S Ito, MA Pipitone, ZA Abdel-Malek

PIGMENT CELL RESEARCH 16(5) 434-447 2003年10月
Rate constants for the first two chemical steps of eumelanogenesis

EJ Land, S Ito, K Wakamatsu, PA Riley

PIGMENT CELL RESEARCH 16(5) 487-493 2003年10月
HPLC analysis of pheomelanin degradation products in human urine

A Takasaki, E Nezirevic, K Arstrand, K Wakamatsu, S Ito, B Kagedal

PIGMENT CELL RESEARCH 16(5) 480-486 2003年10月
Eumelanin and phaeomelanin contents of depigmented and repigmented skin in vitiligo patients

D Parsad, K Wakamatsu, AJ Kanwar, B Kumar, S Ito

BRITISH JOURNAL OF DERMATOLOGY 149(3) 624-626 2003年9月
Comparison of the structural and physical properties of human hair eumelanin following enzymatic or acid/base extraction

Y Liu, VR Kempf, JB Nofsinger, EE Weinert, M Rudnicki, K Wakamatsu, S Ito, JD Simon

PIGMENT CELL RESEARCH 16(4) 355-365 2003年8月
The structure of neuromelanin as studied by chemical degradative methods

K Wakamatsu, K Fujikawa, FA Zucca, L Zecca, S Ito

JOURNAL OF NEUROCHEMISTRY 86(4) 1015-1023 2003年8月
Comparison of phaeomelanin and its precursor 5-S-cysteinyldopa in the serum of melanoma patients

K Wakamatsu, M Yokochi, A Naito, T Kageshita, S Ito

MELANOMA RESEARCH 13(4) 357-363 2003年8月
A chemist's view of melanogenesis

S Ito

PIGMENT CELL RESEARCH 16(3) 230-236 2003年6月
Effects of melanogenesis-inducing nitric oxide and histamine on the production of eumelanin and pheomelanin in cultured human melanocytes

MW Lassalle, S Igarashi, M Sasaki, K Wakamatsu, S Ito, T Horikoshi

PIGMENT CELL RESEARCH 16(1) 81-84 2003年2月
Changes in the proliferation and differentiation of neonetal mouse pink-eyed dilution melanocytes in the presence of excess tyrosine

Pigment Cell Research 16, 619-628 2003年
The neuromelanin of human substantia nigra: structure, synthesis and molecular behaviour

L Zecca, FA Zucca, P Costi, D Tampellini, A Gatti, M Gerlach, P Riederer, RG Fariello, S Ito, M Gallorini, D Sulzer

ADVANCES IN RESEARCH ON NEURODEGENERATION 10 145-155 2003年
DNA damage and melanin content following ultraviolet radiation of human skin from different racial/ethic and photosensitive groups

FASEB Journal 17, 1177-1179 2003年
gamma-Glutamyl transpeptidase and its role in melanogenesis: Redox reactions and regulation of tyrosinase

VA Chaubal, SS Nair, S Ito, K Wakamatsu, MV Mojamdar

PIGMENT CELL RESEARCH 15(6) 420-425 2002年12月
Melanocortin 1 receptor accounts for 50% of variation in hair melanin eumelanin and phaemelanin in a northern European dataset

L Naysmith, T Ha, K Waterston, Y Bisset, A Ray, NF Ianagan, S Ito, K Wakamatsu, JL Rees

JOURNAL OF INVESTIGATIVE DERMATOLOGY 119(3) 758-758 2002年9月
Advanced chemical methods in melanin determination

K Wakamatsu, S Ito

PIGMENT CELL RESEARCH 15(3) 174-183 2002年6月
The usefulness of 4-amino-3-hydroxyphenylalanine as a specific marker of pheomelanin

K Wakamatsu, S Ito, JL Rees

PIGMENT CELL RESEARCH 15(3) 225-232 2002年6月
Evaluation of 5-S-cysteinyidopa as a marker of melanoma progression: 10 years' experience

K Wakamatsu, T Kageshita, M Furue, N Hatta, Y Kiyohara, J Nakayama, T Ono, T Saida, M Takata, T Tsuchida, H Uhara, A Yamamoto, N Yamazaki, A Naito, S Ito

MELANOMA RESEARCH 12(3) 245-253 2002年6月
Human melanocortin 1 receptor variants, receptor function and melanocyte response to UV radiation

MC Scott, K Wakamatsu, S Ito, AL Kadekaro, N Kobayashi, J Groden, R Kavanagh, T Takakuwa, Virador, V, VJ Hearing, ZA Abdel-Malek

JOURNAL OF CELL SCIENCE 115(11) 2349-2355 2002年6月
Stimulation of the proliferation and differentiation of mouse pink-eyed dilution epidermal melanocytes by excess tyrosine in serum-free primary culture

T Hirobe, K Wakamatsu, S Ito, H Abe, Y Kawa, M Mizoguchi

JOURNAL OF CELLULAR PHYSIOLOGY 191(2) 162-172 2002年5月
Effects of genic substitution at the pink-eyed dilution locus on the proliferation and differentiation of mouse epidermal melanocytes in vivo and in vitro

T Hirobe, Y Kawa, M Mizoguchi, S Ito, K Wakamatsu

JOURNAL OF EXPERIMENTAL ZOOLOGY 292(4) 351-366 2002年3月
Molecular and phenotypic analysis of 25 recessive, homozygous-viable alleles at the mouse agouti locus

RJ Miltenberger, K Wakamatsu, S Ito, RP Woychik, LB Russell, EJ Michaud

GENETICS 160(2) 659-674 2002年2月
The neuromelanin of human substantia nigra and its interaction with metals

L Zecca, D Tampellini, A Gatti, R Crippa, M Eisner, D Sulzer, S Ito, R Fariello, M Gallorini

JOURNAL OF NEURAL TRANSMISSION 109(5-6) 663-672 2002年
Influence of alpha-melanocyte-stimulating hormone and of ultraviolet radiation on the transfer of melanosomes to keratinocytes

VM Virador, J Muller, XF Wu, ZA Abdel-Malek, ZX Yu, VJ Ferrans, N Kobayashi, K Wakamatsu, S Ito, JA Hammer, VJ Hearing

FASEB JOURNAL 15(13) 105-+ 2001年11月
5-S-cysteinyldopa as diagnostic tumor marker for uveal malignant melanoma

H Goto, M Usui, K Wakamatsu, S Ito

JAPANESE JOURNAL OF OPHTHALMOLOGY 45(5) 538-542 2001年9月
Effect of increased intracellular melanin concentration on survival of human melanoma cells exposed to different wavelengths of UV radiation

C Kowalczuk, M Priestner, C Baller, A Pearson, N Cridland, R Saunders, K Wakamatsu, S Ito

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY 77(8) 883-889 2001年8月
Molecular and phenotypic analysis of Attractin mutant mice

TM Gunn, T Inui, K Kitada, S Ito, K Wakamatsu, L He, DM Bouley, T Serikawa, GS Barsh

GENETICS 158(4) 1683-1695 2001年8月
DNA damage and melanin production induced by ultraviolet radiation in human skin within various racial/ethnic groups

T Tadokoro, N Kobayashi, J Beer, B Zmudzka, Hearing, V, K Korossy, S Ito, K Wakamatsu

JOURNAL OF INVESTIGATIVE DERMATOLOGY 117(2) 498-498 2001年8月
Tissue factor expression and serum level in patients with melanoma does not correlate with disease progression

T Kageshita, Y Funasaka, M Ichihashi, K Wakamatsu, S Ito, T Ono

PIGMENT CELL RESEARCH 14(3) 195-200 2001年6月
Cyclic oscillations in melanin composition within hairs of baboons

S Ito, K Wakamatsu, N Matsunaga, VJ Hearing, KD Carey, S Anderson, TP Dooley

PIGMENT CELL RESEARCH 14(3) 180-184 2001年6月
Noise-induced hearing loss: the effect of melanin in the stria vascularis

S Bartels, S Ito, DR Trune, AL Nuttall

HEARING RESEARCH 154(1-2) 116-123 2001年4月
Interaction of major coat color gene functions in mice as studied by chemical analysis of eumelanin and pheomelanin

ML Lamoreux, K Wakamatsu, S Ito

PIGMENT CELL RESEARCH 14(1) 23-31 2001年2月
Structural characteristics of human substantia nigra neuromelanin and synthetic dopamine melanins

KL Double, L Zecca, P Costi, M Mauer, C Griesinger, S Ito, D Ben-Shachar, G Bringmann, RG Fariello, P Riederer, M Gerlach

JOURNAL OF NEUROCHEMISTRY 75(6) 2583-2589 2000年12月
The underwhite (uw) locus acts autonomously and reduces the production of melanin

AL Lehman, WK Silvers, N Puri, K Wakamatsu, S Ito, MH Brilliant

JOURNAL OF INVESTIGATIVE DERMATOLOGY 115(4) 601-606 2000年10月
Heterozygous HPS1 mutations in a case of Hermansky-Pudlak syndrome with giant melanosomes

T Horikawa, K Araki, K Fukai, M Ueda, T Ueda, S Ito, M Ichihashi

BRITISH JOURNAL OF DERMATOLOGY 143(3) 635-640 2000年9月
Quantitative trait loci that modify the sootiness of yellow pigmentation in KK-A(y)/a mice

J Suto, K Wakamatsu, H Yamanaka, S Ito, K Sekikawa

MAMMALIAN GENOME 11(8) 639-644 2000年8月
The melanocortin-1 receptor is a key regulator of human cutaneous pigmentation

Z Abdel-Malek, MC Scott, Suzuki, I, A Tada, S Im, L Lamoreux, S Ito, G Barsh, VJ Hearing

PIGMENT CELL RESEARCH 13(Supplement 8) 156-162 2000年
Chemical analysis of melanins and its application to the study of the regulation of melanogenesis

S Ito, K Wakamatsu, H Ozeki

PIGMENT CELL RESEARCH 13(Supplement 8) 103-109 2000年
Interaction of human substantia nigra neuromelanin with lipids and peptides

Luigi Zecca, Patrizia Costi, Claudio Mecacci, Shosuke Ito, Mariarosa Terreni, Sandro Sonnino

Journal of Neurochemistry 74(4) 1758-1765 2000年
Chemical analysis of melanin pigments in feather germs of Japanese quail Bh (black at hatch) mutants

N Shiojiri, T Niwa, K Wakamatsu, S Ito, A Nakamura

PIGMENT CELL RESEARCH 12(4) 259-265 1999年8月
Insect melanogenesis. II. Inability of Manduca phenoloxidase to act on 5,6-dihydroxyindole-2-carboxylic acid

M Sugumaran, R Duggaraju, F Generozova, S Ito

PIGMENT CELL RESEARCH 12(2) 118-125 1999年4月
Cysteine transport in melanosomes from murine melanocytes

SB Potterf, Virador, V, K Wakamatsu, M Furumura, C Santis, S Ito, VJ Hearing

PIGMENT CELL RESEARCH 12(1) 4-12 1999年2月
Catecholamine oxidative products, but not melanin, are produced by Cryptococcus neoformans during neuropathogenesis in mice

L Liu, K Wakamatsu, S Ito, PR Williamson

INFECTION AND IMMUNITY 67(1) 108-112 1999年1月
Does tyrosinase exist in neuromelanin-pigmented neurons in the human substantia nigra?

K Ikemoto, Nagatsu, I, S Ito, RA King, A Nishimura, T Nagatsu

NEUROSCIENCE LETTERS 253(3) 198-200 1998年9月
Pigment cells representing polychromatic colony color in Botrylloides simodensis (Ascidiacea, Urochordata): Cell morphology and pigment substances

E Hirose, T Yoshida, T Akiyama, S Ito, Y Iwanami

ZOOLOGICAL SCIENCE 15(4) 489-497 1998年8月
Comparison of high performance liquid chromatography and stereological image analysis for the quantitation of eumelanins and pheomelanins in melanoma cells

E Donois, Del Marmol, V, K Wakamatsu, S Ito, G Ghanem, JE Surleve-Bazeille

PIGMENT CELL RESEARCH 11(2) 86-93 1998年4月
Chemical degradation of melanins: Application to identification of dopamine-melanin

S Ito, K Wakamatsu

PIGMENT CELL RESEARCH 11(2) 120-126 1998年4月
Comparison of antimelanoma effects of 4-S-cysteaminylphenol and its homologues

S Inoue, K Hasegawa, K Wakamatsu, S Ito

MELANOMA RESEARCH 8(2) 105-112 1998年4月
Melanin biosynthesis in Cryptococcus neoformans

PR Williamson, K Wakamatsu, S Ito

JOURNAL OF BACTERIOLOGY 180(6) 1570-1572 1998年3月

書籍等出版物

Chemistry of Melanins. In "The Pigmentary System. Sec Ed. "

Blackwell Publishing 2006年
Advances in chemical analysis of melanins. In"The Pigmentary System and Its Disorders"(共著)

Oxford University Press, New York 1998年
Spectrophotometric and HPLC characterization of hair melanins(共著)

Excerpta Medica International Congress Series 1096. International Symposium on Melanogenesis and Malignant Melanoma 1996年
Biochemistry and Physiology of Melanin in "Pigmentation and Pigmentary Disorders" (共著)

CRC Press, Inc. 1993年

所属学協会

Works(作品等)

共同研究・競争的資金等の研究課題

一覧へ戻る

伊藤 祥輔

基本情報

研究キーワード

研究分野

学歴

委員歴

受賞

論文

MISC

書籍等出版物

所属学協会

Works(作品等)

共同研究・競争的資金等の研究課題

伊藤祥輔