研究者業績

稲田健一

イナダケンイチ (Ken'ichi Inada)

基本情報

所属: 藤田医科大学医学部医学科教授

学位: 医学博士(東海大学)

J-GLOBAL ID: 200901082865010243
researchmap会員ID: 0000002032

研究キーワード

2

研究分野

2

経歴

1

藤田保健衛生大学医学部医学科第1病理助教授

MISC

129

Mizoshita T, Inada K, Tsukamoto T, Nozaki K, Joh T, Itoh M, Yamamura Y, Ushijima T, Nakamura S, Tatematsu M. Expression of the intestine-specific transcription factors, Cdx1 and Cdx2, correlates shift to an intestinal phenotype in gastric cancer cells.

J Cancer Res Clin Oncol. 130(1) 29-36 2004年
Mizoshita T, Inada K, Tsukamoto T, Nozaki K, Joh T, Itoh M, Yamamura Y, Ushijima T, Nakamura S, Tatematsu M. Expression of the intestine-specific transcription factors, Cdx1 and Cdx2, correlates shift to an intestinal phenotype in gastric cancer cells.

J Cancer Res Clin Oncol. 130(1) 29-36 2004年
Stem cells and gastric cancer: Role of gastric and intestinal mixed intestinal metaplasia

M Tatematsu, T Tsukamoto, K Inada

CANCER SCIENCE 94(2) 135-141 2003年2月
Koike M, Inada K, Nakanishi H, Matsuura A, Nakamura S, Tatematsu M. Cellular differentiation status of epithelial polyps of the colorectum : the gastric foveolar cell-type in hyperplastic polyps.

Histopathology. 42(4) 357-64 2003年
Nozaki K, Shimizu N, Ikehara Y, Inoue M, Tsukamoto T, Inada K, Tanaka H, Kumagai T, Kaminishi M, Tatematsu M. Effect of early eradication on Helicobacter pylori-related gastric carcinogenesis in Mongolian gerbils.

NOZAKI K, SHIMIZU N, IKEHARA Y, INOUE M, TSUKAMOTO T, TANAKA H, KUMAGAI T, KAMINISHI M, TATEMATSU M

Cancer Sci. 94(3) 235-239 2003年
Effect of a tyrosine kinase inhibitor ST1571 in a patient with hepatic metastases from a duodenal gastrointestinal stromal tumor

A Sawaki, K Ohashi, K Yamao, K Inada, Y Shimizu, A Matsuura, T Nakamura, T Suzuki, K Hara, K Okubo, R Ohno

JOURNAL OF GASTROENTEROLOGY 38(7) 690-694 2003年
Mizoshita T, Tsukamota T, Nakanishi H, Inada K, Ogasawara N, Joh T, Itoh M, Yamamura Y, Tatematsu M. Expression of Cdx2 and the phenotype of advanced gastric cancers : relationship with prognosis.

J Cancer Res Clin Oncol. 129(12) 727-34 2003年
Nishiumi N, Abe Y, Inoue Y, Hatanaka H, Inada K, Kijima H, Yamazaki H, Tatematsu M, Ueyama Y, Iwasaki M, Inoue H, Nakamura M. Use of 11p15 mucins as prognostic factors in small adenocarcinoma of the lung.

Clin Cancer Res. 9(15) 5616-9 2003年
Tsukamoto T, Inada K, Tanaka H, Mizoshita T, Mihara M, Ushijima T, Yamamura Y, Nakamura S, Tatematsu M. Down-regulation of a gastric transcription factor, Sox2, and ectopic expression of intestinal homeobox genes, Cdx1 and Cdx2 : inverse correlation du・・・

J Cancer Res Clin Oncol. 2003年

Tsukamoto T, Inada K, Tanaka H, Mizoshita T, Mihara M, Ushijima T, Yamamura Y, Nakamura S, Tatematsu M. Down-regulation of a gastric transcription factor, Sox2, and ectopic expression of intestinal homeobox genes, Cdx1 and Cdx2 : inverse correlation during progression from gastric/intestinal-mixed to complete intestinal metaplasia.
Koike M, Inada K, Nakanishi H, Matsuura A, Nakamura S, Tatematsu M. Cellular differentiation status of epithelial polyps of the colorectum : the gastric foveolar cell-type in hyperplastic polyps.

Histopathology. 42(4) 357-64 2003年
Tatematsu M, Tsukamoto T, Inada K. Stem cells and gastric cancer : role of gastric and intestinal mixed intestinal metaplasia.

Cancer Sci. 94(2) 135-141 2003年
Nozaki K, Shimizu N, Ikehara Y, Inoue M, Tsukamoto T, Inada K, Tanaka H, Kumagai T, Kaminishi M, Tatematsu M. Effect of early eradication on Helicobacter pylori-related gastric carcinogenesis in Mongolian gerbils.

Cancer Sci. 94(3) 235-239 2003年
Sawaki A, Ohashi K, Yamao K, Inada K, Shimizu Y, Matsuura A, Nakamura T, Suzuki T, Hara K, Okubo K, Ohno R. Effect of a tyrosine kinase inhibitor STI571 in a patient with hepatic metastases from a duodenal gastrointestinal stromal tumor.

J Gastroenterol 38(7) 690-694 2003年
Mizoshita T, Tsukamota T, Nakanishi H, Inada K, Ogasawara N, Joh T, Itoh M, Yamamura Y, Tatematsu M. Expression of Cdx2 and the phenotype of advanced gastric cancers : relationship with prognosis.

J Cancer Res Clin Oncol. 129(12) 727-34 2003年
Nishiumi N, Abe Y, Inoue Y, Hatanaka H, Inada K, Kijima H, Yamazaki H, Tatematsu M, Ueyama Y, Iwasaki M, Inoue H, Nakamura M. Use of 11p15 mucins as prognostic factors in small adenocarcinoma of the lung.

Clin Cancer Res. 9(15) 5616-9 2003年
Tsukamoto T, Inada K, Tanaka H, Mizoshita T, Mihara M, Ushijima T, Yamamura Y, Nakamura S, Tatematsu M. Down-regulation of a gastric transcription factor, Sox2, and ectopic expression of intestinal homeobox genes, Cdx1 and Cdx2 : inverse correlation du・・・

J Cancer Res Clin Oncol. 2003年

Tsukamoto T, Inada K, Tanaka H, Mizoshita T, Mihara M, Ushijima T, Yamamura Y, Nakamura S, Tatematsu M.<br /> Down-regulation of a gastric transcription factor, Sox2, and ectopic expression of intestinal homeobox genes, Cdx1 and Cdx2 : inverse correlation during progression from gastric/intestinal-mixed to complete intestinal metaplasia.
Sugiyama Y, Kato T, Nakazato H, Ito K, Mizuno I, Kanemitsu T, Matsumoto K, Yamaguchi A, Nakai K, Inada K, Tatematsu M. Retrospective study on thymidylate synthase as a predictor of outcome and sensitivity to adjuvant chemotherapy in patients with curat・・・

Anticancer Drugs. 13(9) 931-8 2002年

Sugiyama Y, Kato T, Nakazato H, Ito K, Mizuno I, Kanemitsu T, Matsumoto K, Yamaguchi A, Nakai K, Inada K, Tatematsu M. Retrospective study on thymidylate synthase as a predictor of outcome and sensitivity to adjuvant chemotherapy in patients with curatively resected colorectal cancer.
Synergistic Promoting Effects of Helicobacter pylori Infection and High-salt Diet on Gastric Carcinogenests in Mongolian Gerbils

Jpn. J. Cancer Res. 93,1083-1089 2002年
Reversibility of heterotopic proliferative glands in glandular stomach of Helicobacter pylori-infected Mongolian

Gerbils on eradication, Jpn. J. Cancer Res. 93,374-381 2002年
Independent variation in susceptibilities of six different mouse strains to induction of pepsinogh-altered pyloric glands and gastric tumor intestinalization by N-methyl-N-nitrosoureer

Cancer Lett 179,121-132 2002年
Helicobacter pylori 感染と胃癌発生

日本消化器病学会雑誌 99(3), 247-252 2002年
Sugiyama Y, Kato T, Nakazato H, Ito K, Mizuno I, Kanemitsu T, Matsumoto K, Yamaguchi A, Nakai K, Inada K, Tatematsu M. Retrospective study on thymidylate synthase as a predictor of outcome and sensitivity to adjuvant chemotherapy in patients with curat・・・

Anticancer Drugs. 13(9) 931-8 2002年

Sugiyama Y, Kato T, Nakazato H, Ito K, Mizuno I, Kanemitsu T, Matsumoto K, Yamaguchi A, Nakai K, Inada K, Tatematsu M.<br /> Retrospective study on thymidylate synthase as a predictor of outcome and sensitivity to adjuvant chemotherapy in patients with curatively resected colorectal cancer.
Synergistic Promoting Effects of Helicobacter pylori Infection and High-salt Diet on Gastric Carcinogenests in Mongolian Gerbils

Jpn. J. Cancer Res. 93,1083-1089 2002年
A phenotypic shift from gastric-intestinal to solely intestinal cell types in intestinal metaplasia in rat stomach following treatment with X-rays

Hirofumi Yuasa, Ken-Ichi Inada, Hiromitsu Watanabe, Masae Tatematsu

Journal of Toxicologic Pathology 15(2) 85-93 2002年
Reversibility of heterotopic proliferative glands in glandular stomach of Helicobacter pylori-infected Mongolian

Gerbils on eradication, Jpn. J. Cancer Res. 93,374-381 2002年
Independent variation in susceptibilities of six different mouse strains to induction of pepsinogh-altered pyloric glands and gastric tumor intestinalization by N-methyl-N-nitrosoureer

Cancer Lett. 179,121-132 2002年
Polymorphisms of Two Fucosyltransberase Genes (Lewis and Secretor Genes) Involving Type I Lewis Antigens Are Associated with the Presence of Anti-Helicobacter pylori IgG Antibody

Cancer Epidemiol. Biomark. Prev. 10,971-977 2001年
Real-time reverse transcriptase polymerase chain reaction of urinary cytokeratin 20 detects transitional cell carcinoma cells.

J.Urol. 166, 2134-2141 2001年
Squential histopathological changes in vivo after suicide gene therapy of gastric cancer induced by N-methyl-N'-nitro-N-nitrosoguanidine in rats.

Jpn.J.Cancer Res. 92, 673-679 2001年
Identification of Paneth cells in pyloric glands associated with gastric and intestinal mixed type intestinal metaplasia of the human stomach.

Virchows Arch. 439, 14-20 2001年
Polymorphisms of Two Fucosyltransberase Genes (Lewis and Secretor Genes) Involving Type I Lewis Antigens Are Associated with the Presence of Anti-Helicobacter pylori IgG Antibody

Cancer Epidemiol. Biomark. Prev. 10,971-977 2001年
Real-time reverse transcriptase polymerase chain reaction of urinary cytokeratin 20 detects transitional cell carcinoma cells.

J.Urol. 166, 2134-2141 2001年
Squential histopathological changes in vivo after suicide gene therapy of gastric cancer induced by N-methyl-N'-nitro-N-nitrosoguanidine in rats.

Jpn.J.Cancer Res. 92, 673-679 2001年
Identification of Paneth cells in pyloric glands associated with gastric and intestinal mixed type intestinal metaplasia of the human stomach.

Virchows Arch 439, 14-20 2001年
Expression of cathepsin e and its suppression with intestinalization in epithelial cells and tumor cells in rat glandular stomach treated with N-methyl-N'-nitro-N-nitrosoguanidine

Hirofumi Yuasa, Satoshi Yoneyama, Masao Ichinose, Kazumasa Miki, Tetsuya Tsukamoto, Ken-Ichi Inada, Masae Tatematsu

Journal of Toxicologic Pathology 14(1) 29-35 2001年
Mouse strain susceptibility to diethylnitrosamine induced hepatocarcinogenesis is cell autonomous whereas sex-susceptibility is due to the micro-environment:analysis with C3H<->BALB/c sexually chimeric mice.

Jpn.J.Cancer Res. 91, 665-673 2000年
Summation of initiation activities of low doses of the non-hepatocarcinogen 1.2-dimethylhydrazine in the liver after carbon tetrachloride administration.

Cancer Letters 148, 59-63 2000年
Eradication diminishes enhancing effects of Helicobacter pylori infection on glandular stomach carcinogenesis in Mongolian gerbils.

Cancer Res. 60, 1512-1514, 2000年
Mouse strain susceptibility to diethylnitrosamine induced hepatocarclinogenesis is cell autonomous whereas sex-susceptibility is due to the micro-environment:analysis with C3H<->BALB/c sexually chimeric mice.

Jpn.J.Cancer Res. 91, 665-673 2000年
Summation of initiation activities of low doses of the non-hepatocarcinogen 1.2-dimethylhydrazine in the liver after carbon tetrachloride administration.

Cancer Letters 148, 59-6 2000年
Eradication diminishesenhancing effects of Helicobacter pylori infection on glandular stomach carcinogenesis in Mongolian gerbils.

Cancer Res. 60, 1512-1514 2000年
Induction of apoptosis in metastatic foci from human gastric cancer xenografts in nude mice and reduction of circulating tumor cells in blood by 5-FU and 1-hexylcarbamoyl-5-fluorouracil.

J. Cancer Res. Clin. Oncol. 125, 660-668 1999年
Helicobacter pylori infection enhances glandular stomach carcinogenesis in Mongolian gerbils treated with chemical carcinogens.

Carcinogenesis: 20, 4, 669-676 1999年
Effects of low dose catechol on glandular stomach carcinogenesis in BALB/c mice initiated with N-methyl-N-nitrosourea.

Cancer Lett. 139, 167-172 1999年
Chemosensitivity of micrometastases and circulating tumor cells to uracil and tegafur as evaluated using LacZ gene-tagged Lewis lung carcinoma cell.

Cancer Lett. 142, 31-41, 1999年
Induction of apoptosis in metastatic foci from human gastric cancer xenografts in nude mice and reduction of circulating tumor cells in blood by 5-FU and 1-hexylcarbamoyl-5-fluorouracil.

J. Cancer Res. Clin. Oncol. 125, 660-668 1999年
Helicobacter pylori infection enhances glandular stomach carcinogenesis in Mongolian gerbils treated with chemical carcinogens.

Carcinogenesis: 20, 4, 669-676, 1999年
Effects of low dose catechol on glandular stomach carcinogenesis in BALB/c mice initiated with N-methyl-N-nitrosourea.

Cancer Lett. 139, 167-172 1999年
Chemosensitivity of micrometastases and circulating tumor cells to uracil and tegafur as evaluated using LacZ gene-tagged Lewis lung carcinoma cell.

Cancer Lett. 142, 31-41 1999年
Phenotypic shift in human differentiated gastric cancers from gastric to intestinal epithelial cell type during disease progression.

Gastric Cancer 1, 134-141 1998年

書籍等出版物

39

器官培養法を用いたヒト胃粘膜腸上皮化生腺管の細胞動態 -腺管分離法による解析-

消化器癌発生学会編、消化器癌の発生と進展10、靖文社、東京、 1998年
p53 knockoutマウスにおけるN-methyl-N-nitrosourea誘発胃癌

消化器癌発生学会編、消化器癌の発生と進展10、靖文社、東京 1998年
MNU誘発キメラマウス腺胃腫瘍の組織発生と発育進展形式の検討

消化器癌発生学会編、消化器癌の発生と進展10、靖文社、東京、 1998年
Helicobacter pylori感染の胃癌発生増強作用 -スナネズミモデルの検討-

消化器癌発生学会編、消化器癌の発生と進展10、靖文社、東京、 1998年
Helicobacter pylori infection enhances glandular stomach carcinogenesis in Mongolian gerbils treated with chemical carcinogens.

J. Jpn. Society Gastroenterol. Carcinogenesis (in Japanese) 1998年

もっとみる

所属学協会

7

もっとみる

共同研究・競争的資金等の研究課題

4

消化管粘膜における細胞分化

共同研究 1999年
Celluler differentiation of gastrointestinal mucosa

Cooperative Research 1999年
腸上皮化生

科学研究費補助金 1995年
Intestinal metaplasia

Grant-in-Aid for Scientific Research 1995年

一覧へ戻る

メニュー

▶大学ホームページに戻る

▶Return to University HOME