Mitsuyasu Itoh

(伊藤光泰)

Profile Information

Affiliation: Professor of Medicine, School of Medicine, Faculty of Medicine, Fujita Health University

Degree: (BLANK)

J-GLOBAL ID: 200901010157792273
researchmap Member ID: 1000049261

Research Interests

Research Areas

Life sciences / Metabolism and endocrinology /

Education

- 1978

Nagoya University
- 1978

Graduate School, Division of Medicine, Nagoya University
- 1974

School of Medicine, Nagoya University
- 1974

Faculty of Medicine, Nagoya University

Awards

Nov, 2011

Miyake Prize, The Japan Thyroid Association

ITOH Mitsuyasu

Papers

Oral alendronate can suppress bone turnover but not fracture in kidney transplantation recipients with hyperparathyroidism and chronic kidney disease

Sakura Yamamoto, Atsushi Suzuki, Hitomi Sasaki, Sahoko Sekiguchi-Ueda, Shogo Asano, Megumi Shibata, Nobuki Hayakawa, Shuji Hashimoto, Kiyotaka Hoshinaga, Mitsuyasu Itoh

JOURNAL OF BONE AND MINERAL METABOLISM, 31(1) 116-122, Jan, 2013 Peer-reviewed
Effects of aripiprazole and clozapine on the treatment of glycolytic carbon in PC12 cells

Akira Ota, Akira Nakashima, Yoko S. Kaneko, Keiji Mori, Hiroshi Nagasaki, Takeshi Takayanagi, Mitsuyasu Itoh, Kazunao Kondo, Toshiharu Nagatsu, Miyuki Ota

JOURNAL OF NEURAL TRANSMISSION, 119(11) 1327-1342, Nov, 2012 Peer-reviewed
Some fine-structural findings on the thyroid gland in Apc (1638T/1638T) mice that express a C-terminus lacking truncated Apc

Atsushi Yokoyama, Ryuji Nomura, Masafumi Kurosumi, Atsushi Shimomura, Takanori Onouchi, Akiko Iizuka-Kogo, Ron Smits, Riccardo Fodde, Mitsuyasu Itoh, Takao Senda

MEDICAL MOLECULAR MORPHOLOGY, 45(3) 161-167, Sep, 2012 Peer-reviewed
Relative Levels of the Inflammatory Cytokine TNF alpha and the Soluble CD40 Ligand Profile in Serum Correlate with the Thyrotoxic Activity of Graves' Disease

Keiko Yamamoto, Mitsuyasu Itoh, Tomoko Okamura, Maiko Kimura, Atsushi Yokoyama, Yasumasa Yoshino, Masaki Makino, Nobuki Hayakawa, Atsushi Suzuki

THYROID, 22(5) 516-521, May, 2012 Peer-reviewed
Use of a new high-sensitivity assay for cardiac troponin T to stratify the risk of cardiovascular disease in outpatients with type-2 diabetes

Shogo Asano, Atsushi Suzuki, Junnichi Ishii, Sahoko Sekiguchi-Ueda, Megumi Shibata, Yasumasa Yoshino, Kazuhiro Nakamura, Yasukazu Akiyama, Fumihiko Kitagawa, Toshiaki Sakuishi, Takashi Fujita, Mitsuyasu Itoh

Diabetology International, 3(1) 29-36, Mar, 2012 Peer-reviewed
The C-terminal domain of the adenomatous polyposis coli (Apc) protein is involved in thyroid morphogenesis and function

Atsushi Yokoyama, Ryuji Nomura, Masafumi Kurosumi, Atsushi Shimomura, Takanori Onouchi, Akiko Iizuka-Kogo, Ron Smits, Naohisa Oda, Riccardo Fodde, Mitsuyasu Itoh, Takao Senda

MEDICAL MOLECULAR MORPHOLOGY, 44(4) 207-212, Dec, 2011 Peer-reviewed
Comparison of Efficacy of Pitavastatin and Colestimide in Japanese Patients with Diabetes Mellitus Complicated by Hyperlipidemia and Metabolic Syndrome

T. Kato, K. Inagaki, Y. Sawai, H. Kanayama, N. Katada, M. Itoh

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, 119(9) 554-558, Oct, 2011 Peer-reviewed
Incisor Enamel Formation is Impaired in Transgenic Rats Overexpressing the Type III NaPi Transporter Slc20a1

Hirotaka Yoshioka, Yuji Yoshiko, Tomoko Minamizaki, Sayaka Suzuki, Yoshiro Koma, Asako Nobukiyo, Yusuke Sotomaru, Atsushi Suzuki, Mitsuyasu Itoh, Norihiko Maeda

CALCIFIED TISSUE INTERNATIONAL, 89(3) 192-202, Sep, 2011 Peer-reviewed
High prevalence of hypovitaminosis D in pregnant Japanese women with threatened premature delivery

Megumi Shibata, Atsushi Suzuki, Takao Sekiya, Sahoko Sekiguchi, Shogo Asano, Yasuhiro Udagawa, Mitsuyasu Itoh

JOURNAL OF BONE AND MINERAL METABOLISM, 29(5) 615-620, Sep, 2011 Peer-reviewed
Phosphate overload induces podocyte injury via type III Na-dependent phosphate transporter

Sahoko Sekiguchi, Atsushi Suzuki, Shogo Asano, Keiko Nishiwaki-Yasuda, Megumi Shibata, Shizuko Nagao, Naoki Yamamoto, Mutsushi Matsuyama, Yutaka Sato, Kunimasa Yan, Eishin Yaoita, Mitsuyasu Itoh

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 300(4) F848-F856, Apr, 2011 Peer-reviewed
Effects of transgenic Pit-1 overexpression on calcium phosphate and bone metabolism

Atsushi Suzuki, Patrick Ammann, Keiko Nishiwaki-Yasuda, Sahoko Sekiguchi, Shogo Asano, Shizuko Nagao, Ryosuke Kaneko, Masumi Hirabayashi, Yutaka Oiso, Mitsuyasu Itoh, Joseph Caverzasio

JOURNAL OF BONE AND MINERAL METABOLISM, 28(2) 139-148, Mar, 2010 Peer-reviewed
Comparative Study of Low-dose Pioglitazone or Metformin Treatment in Japanese Diabetic Patients with Metabolic Syndrome

T. Kato, Y. Sawai, H. Kanayama, H. Taguchi, T. Terabayashi, F. Taki, K. Yamada, Y. Yamazaki, N. Hayakawa, A. Suzuki, N. Oda, N. Katada, M. Itoh

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, 117(10) 593-599, Nov, 2009 Peer-reviewed
Effects of prostaglandin D-2 on Na-dependent phosphate transport activity and its intracellular signaling mechanism in osteoblast-like cells

Shogo Asano, Atsushi Suzuki, Sahoko Sekiguchi, Keiko Nishiwaki-Yasuda, Megumi Shibata, Mitsuyasu Itoh

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 81(4) 247-251, Oct, 2009 Peer-reviewed
Thyroglobulin may affect telomerase activity in thyroid follicular cells

Akio Nagasaka, Naohisa Oda, Akira Nakai, Keiko Hotta, Mutsuko Nagata, Taiya Kato, Atsushi Suzuki, Mitsuyasu Itoh, Hitoshi Miura, Motoo Hakuta, Shonen Yoshida, Yatsuka Hibi, Katsumi Iwase

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 24(2) 524-530, 2009 Peer-reviewed
Insulinoma cell calcium-sensing receptor influences insulin secretion in a case with concurrent familial hypocalciuric hypercalcemia and malignant metastatic insulinoma

Yasunaga Ono, Naohisa Oda, Shin Ishihara, Atsushi Shimomura, Nobuki Hayakawa, Atsushi Suzuki, Akihiko Horiguchi, Takao Senda, Shuichi Miyakawa, Mitsuyasu Itoh

EUROPEAN JOURNAL OF ENDOCRINOLOGY, 159(1) 81-86, Jul, 2008 Peer-reviewed
2,4-Diamino-6-hydroxypyrimidine (DAHP) suppresses cytokine-induced VCAM-1 expression on the cell surface of human umbilical vein endothelial cells in a BH4-independent manner

Kazuhisa Ikemoto, Takashi Matsumoto, Masatsugu Ohtsuki, Mitsuyasu Itoh, Shin Tada, Yasuhiro Udagawa, Chiho Sumi-Ichinose, Kazunao Kondo, Takahide Nomura

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1780(7-8) 960-965, Jul, 2008 Peer-reviewed
Severe hypoglycaemia in a person with insulin autoimmune syndrome accompanied by insulin receptor anomaly type B

T. Kato, M. Itoh, J. Hanashita, T. Itoi, T. Matsumoto, Y. Ono, S. Imamura, N. Hayakawa, A. Suzuki, Y. Mizutani, Y. Uchigata, N. Oda

DIABETIC MEDICINE, 24(11) 1279-1281, Nov, 2007 Peer-reviewed
Subclinical hypothyroidism is related to lower heel QUS in postmenopausal women.

ITOH Mitsuyasu

Endocrine Journal, 54(4) 625-630, 2007 Peer-reviewed
Vasopressin stimulates Na-dependent phosphate transport and calcification in rat aortic smooth muscle cells.

ITOH Mitsuyasu

Endocrine Journal, 54(1) 103-112, 2007 Peer-reviewed
Enhanced expression of the inorganic phosphate transporter Pit-1 is involved in BMP-2-Induced matrix mineralization in osteoblast-like cells

A Suzuki, C Ghayor, J Guicheux, D Magne, S Quillard, A Kakita, Y Ono, Y Miura, Y Oiso, M Itoh, J Caverzasio

JOURNAL OF BONE AND MINERAL RESEARCH, 21(5) 674-683, May, 2006 Peer-reviewed
Hypovitaminosis D in type 2 diabetes mellitus: Association with microvascular complications and type of treatment

ITOH Mitsuyasu

Endocrine Journal, 53(4) 503-510, 2006 Peer-reviewed
Alteration of thyroid aldolase isozymes in various thyroid disorders

K Iwase, M Hamada, K Kato, H Yamamoto, N Kobayashi, T Tsujimura, Y Himeno, N Yamazaki, A Inagaki, S Jinbo, A Nagasaka, M Itoh

ENDOCRINOLOGIST, 15(4) 213-218, Jul, 2005
Seasonal changes of serum 25-hydroxyvitamin D and intact parathyroid hormone levels in a normal Japanese population

Y Ono, A Suzuki, M Kotake, XL Zhang, K Nishiwaki-Yasuda, Y Ishiwata, S Imamura, M Nagata, S Takamoto, M Itoh

JOURNAL OF BONE AND MINERAL METABOLISM, 23(2) 147-151, Mar, 2005
Changes in cyclic nucleotide phosphodiesterase activity and calmodulin concentration in heart muscle of cardiomyopathic hamsters

R Masunaga, A Nagasaka, Y Sawai, N Hayakawa, A Nakai, K Hotta, Y Kato, H Hishida, H Takahashi, M Naka, Y Shimada, T Tanaka, H Hidaka, M Itoh

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 37(3) 767-774, Sep, 2004
Expression of erbB receptors mRNA in thyroid tissues

S Kato, T Kobayashi, K Yamada, K Nishii, H Sawada, H Ishiguro, M Itoh, H Funahashi, A Nagasaka

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1673(3) 194-200, Aug, 2004
A stable prostacyclin analogue reduces high serum TNF-alpha levels in diabetic patients

K Fujiwara, A Nagasaka, M Nagata, K Yamamoto, S Imamura, N Oda, Y Sawai, N Hayakawa, A Suzuki, M Itoh

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, 112(7) 390-394, Jul, 2004
Possible involvement of p38 MAP kinase in prostaglandin E1-induced ALP activity in osteoblast-like cells

A Kakita, A Suzuki, Y Ono, Y Miura, M Itoh, Y Oiso

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 70(5) 469-474, May, 2004
Stimulation of Na-dependent phosphate transport by platelet-derived growth factor in rat aortic smooth muscle cells

A Kakita, A Suzuki, K Nishiwaki, Y Ono, M Kotake, Y Ariyoshi, Y Miura, M Itoh, Y Oiso

ATHEROSCLEROSIS, 174(1) 17-24, May, 2004
The relationship between glycemic control and plasma vascular endothelial growth factor and endothelin-1 concentration in diabetic patients

H Kakizawa, M Itoh, Y Itoh, S Imamura, Y Ishiwata, T Matsumoto, K Yamamoto, T Kato, Y Ono, M Nagata, N Hayakawa, A Suzuki, Y Goto, N Oda

METABOLISM-CLINICAL AND EXPERIMENTAL, 53(5) 550-555, May, 2004
Tetrahydrobiopterin biosynthesis in white and brown adipose tissues is enhanced following intraperitoneal administration of bacterial lipopolysaccharide

K Fujiwara, K Mori, YS Kaneko, A Nakashima, A Nagasaka, M Itoh, A Ota

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1670(3) 181-198, Feb, 2004
Alteration of urinary sorbitol excretion in WBN-Kob diabetic rats-treatment with an aldose reductase inhibitor.（共著）

Journal of Endocrinology, 181, 429-435, 2004
Possible role of VEGF in the progression of kidney disease in streptozotocin (STZ)-induced diabetic rats: Effects of an ACE inhibitor and an angiotensin II receptor antagonist.（共著）

Hormone and Metabolic Research, 36, 453-457, 2004
Urinary sorbitol measurement and the effect of an aldose reductase inhibitor on its concentration in the diabetic state

Nakano, I, T Tsugawa, R Shinohara, F Watanabe, T Fujita, M Nagata, T Kato, Y Himeno, T Kobayashi, K Fujiwara, M Nagata, M Itoh, A Nagasaka

JOURNAL OF DIABETES AND ITS COMPLICATIONS, 17(6) 337-342, Nov, 2003
Stimulatory effect of prostaglandin F-2 alpha on Na-dependent phosphate transport in osteoblast-like cells

Sato, I, A Suzuki, A Kakita, Y Ono, Y Miura, M Itoh, Y Oiso

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 68(5) 311-315, May, 2003
cGMP inhibits GTP cyclohydrolase I activity and biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells.（共著）

Journal of Pharmacological Sciences, 93, 265-271, 2003
Genetic variations in calpain-10 gene are not a major factor in the occurrence of type 2 diabetes in Japanese

Y Horikawa, N Oda, L Yu, S Imamura, K Fujiwara, M Makino, Y Seino, M Itoh, J Takeda

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 88(1) 244-247, Jan, 2003
A calcium-deficient diet caused decreased bone mineral density and secondary elevation of estrogen in aged male rats - Effect of menatetrenone and elcatonin

S Kato, T Mano, T Kobayashi, N Yamazaki, Y Himeno, K Yamamoto, M Itoh, N Harada, A Nagasaka

METABOLISM-CLINICAL AND EXPERIMENTAL, 51(10) 1230-1234, Oct, 2002
Distinctive response of thyroid-infiltrating mononuclear cells to B cell activation through CD40 and interleukin-4 in Graves' patients

M Itoh, K Uchimura, K Yamamoto, M Makino, S Imamura, T Kobayashi, K Fujiwara, T Kato, N Hayakawa, Y Sawai, A Nagasaka, K Iwase, T Nomura, Y Hagino

CYTOKINE, 19(3) 107-114, Aug, 2002
Distinctive response of thyroid-infiltrating mononuclear cells to B cell activation through CD40 and interleukin-4 in Graves' patients

M Itoh, K Uchimura, K Yamamoto, M Makino, S Imamura, T Kobayashi, K Fujiwara, T Kato, N Hayakawa, Y Sawai, A Nagasaka, K Iwase, T Nomura, Y Hagino

CYTOKINE, 19(3) 107-114, Aug, 2002 Peer-reviewed
Lung cancer associated with hypercalcemia induced by concurrently elevated parathyroid hormone and parathyroid hormone-related protein levels

K Uchimura, T Mokuno, A Nagasaka, N Hayakawa, T Kato, N Yamazaki, T Kobayashi, M Nagata, M Kotake, M Itoh, T Tsujimura, K Iwase

METABOLISM-CLINICAL AND EXPERIMENTAL, 51(7) 871-875, Jul, 2002
Peripheral injection of resperidone, an atypical antipsychotic, alters the body weight gain of rats.（共著）

Clinical & Experimental Pharmacology & Physiology, 29(11), 980-989, 2002
Changes of endothelin in streptozotocin-induced diabetic rats: effects of an angiotensin converting enzyme inhibitor, enalapril maleate.（共著）

Journal of endocrinology, 175(1), 233-239, 2002
Hormonal regulation of DNA polymerase β activity and expression in rat adrenal glands and testes.（共著）

Molecular and Cellular Endocrinology, 192, 127-132, 2002
The effects of CD40- and interleukin (IL-4)-activated CD23+ cells on the production of IL-10 by mononuclear cells in Graves' disease: the role of CD8+ cells.（共著）

Clinical & Experimental Immunology, 128, 308-312, 2002
CAMP inhibits cytokine-induced biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells（共著）

Life Sciences, 70, 2187-2198, 2002
Alteration of Endothelin-1 concentration in STZ-induced Diabetic Rat Nephropathy（共著）

Hormone Research, 56, 165-171, 2001
Effect of eicosapentaenoic acid ethyl ester on hypothyroid function（共著）

Journal of Endocrinology, 171, 259-265, 2001
The therapeutic effect of Lipo PGE, on diabetic nearopathy - changes in endothelin and various angiopathic factors.（共著）

Prostaglandins & Other Lipid Mediators, 66, 221-234, 2001
Polymorphisms of the Insulin Gene Among Japanese Subjects.（共著）

Metabolism, 50(6), 631-634, 2001

Misc.

Changes in cyclic nucleotide phosphodiesterase activity and calmodulin concentration in heart muscle of cardiomyopathic hamsters

R Masunaga, A Nagasaka, Y Sawai, N Hayakawa, A Nakai, K Hotta, Y Kato, H Hishida, H Takahashi, M Naka, Y Shimada, T Tanaka, H Hidaka, M Itoh

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 37(3) 767-774, Sep, 2004
A stable prostacyclin analogue reduces high serum TNF-alpha levels in diabetic patients

K Fujiwara, A Nagasaka, M Nagata, K Yamamoto, S Imamura, N Oda, Y Sawai, N Hayakawa, A Suzuki, M Itoh

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, 112(7) 390-394, Jul, 2004
Possible involvement of p38 MAP kinase in prostaglandin E1-induced ALP activity in osteoblast-like cells

A Kakita, A Suzuki, Y Ono, Y Miura, M Itoh, Y Oiso

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 70(5) 469-474, May, 2004
Stimulation of Na-dependent phosphate transport by platelet-derived growth factor in rat aortic smooth muscle cells

A Kakita, A Suzuki, K Nishiwaki, Y Ono, M Kotake, Y Ariyoshi, Y Miura, M Itoh, Y Oiso

ATHEROSCLEROSIS, 174(1) 17-24, May, 2004
Tetrahydrobiopterin biosynthesis in white and brown adipose tissues is enhanced following intraperitoneal administration of bacterial lipopolysaccharide

K Fujiwara, K Mori, YS Kaneko, A Nakashima, A Nagasaka, M Itoh, A Ota

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1670(3) 181-198, Feb, 2004

Books and Other Publications

Fructosamine as an Index of Glycemic Control and its Relationships to Diabetic Complications‘jointly worked’

The Organizing Committee : 'Glycated Proteins in Diabetes Mellitus' Symposium 1988, 1990
Iodide potentiates a growth-promoting activity of Epidermal growth factor in human thyroid cells in monolayer culture(共著)

Elsevier Science Publishers "The thyroid 1988", 1988
Lymphoblastogenesis to Specific Antigens and the Role of Monocytes in Diabetes with Positive Islet Cell Surface Antibodies (ICSA) In : Best approach to the ideal therapy of diabetes mellitus‘jointly worked’

Elsevies Science Publishers BV, 1987
Secretion of Glucagon In : The Islets of Langerhans‘jointly worked’

Academic Press, 1981

Professional Memberships

Research Projects

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