SUGAMA JUNKO

AIM: To identify the competencies required for hospital-based WOC nurses to provide direct pressure injury (PI) care in home care settings in Japan. DESIGN: Mixed methods convergent design. METHODS: The qualitative strand used a descriptive design to explore competencies for overcoming barriers faced by hospital-based WOC nurses when providing PI care at home. The quantitative strand used a cross-sectional design to assess competencies in organising the hospital PI management system. RESULTS: Six competencies were identified: (1) Establish relationships with home healthcare professionals; (2) Promote hospital-based WOC nurse's expertise to home healthcare professionals; (3) Collaborate with the regional medical liaison office in WOC nurse's hospital; (4) Involve hospital administrators in home PI management; (5) Utilise social media/Information and Communication Technology for patient or home-visiting nurse communication; and (6) Utilise public or academic support projects to facilitate home-based activities. The median scoring rate for each medical staff domain on the revised Collaboration Competency Scale for WOC Nurses ranged from 80% to 91%. CONCLUSION: The results of this study can serve as a practical resource to help WOC nurses expand their activities into home-care settings. IMPLICATIONS FOR THE PROFESSION: Their ability to coordinate with staff and manage PI care within hospitals supports active engagement in home care, improving continuity and quality. IMPACT: This study addressed the issue that many hospital-based WOC nurses cannot visit patients at home. The competencies identified may enable these nurses to expand their role into home care. REPORTING METHOD: This study followed EQUATOR guidelines, with the STROBE Statement applied to the quantitative part and the COREQ checklist to the qualitative part. PATIENT OR PUBLIC CONTRIBUTION: Patients or the public were not involved in the study's design, conduct, or reporting.

OBJECTIVES: The taxane chemotherapeutic agent docetaxel has been used as a therapy for various cancers. Some patients receiving docetaxel develop serious problems with fluid retention, which leads to peripheral edema formation, reducing the patient's quality of life. This study investigated the effect of docetaxel administration on fluid dynamics in mice as a step toward developing advanced preventive measures in nursing. METHODS: Mice were administered 10 mg/kg/day of docetaxel intravenously for 5 days as the intervention group or with normal saline as the control group. To investigate fluid dynamics on day 5, the leakage of blood plasma, interstitial fluid volume, and fluid transportation capacity into lymph vessels were evaluated and compared between the two groups. RESULTS: The Miles assay with Evans Blue, an albumin-binding dye, revealed that leakage of blood plasma was significantly increased in the control group compared with the intervention group (p<0.01). Results of the interstitial fluid volume and fluid transportation capacity were similar between the two groups, but the fluid transportation capacity tended to be higher in the intervention group. CONCLUSIONS: Docetaxel administration in our mouse model caused the leakage of blood plasma without proteins from the blood vessels into the interstitial tissues, which appeared at the initial stage of edema formation. This model might be useful for assessing the leakage of blood plasma and, subsequently, the development of preventive measures against edema formation.