Curriculum Vitaes

Takahide Nomura

(野村隆英)

Profile Information

Affiliation: President, School of Medicine, Faculty of Medicine, Department of Pharmacology, Fujita Health University

Degree: (BLANK)

J-GLOBAL ID: 200901093104640768
researchmap Member ID: 1000102461

Research Interests

2

Research Areas

1

Life sciences / Pharmacology /

Education

4

- 1981

Nagoya University
- 1981

Graduate School, Division of Medicine, Nagoya University
- 1975

School of Medicine, Nagoya University
- 1975

Faculty of Medicine, Nagoya University

Committee Memberships

2

Awards

1

1991

坂幹雄賞

Misc.

29

Suppressed expression of GTP cyclohydrolase I mRNA and accelerated expression of inducible nitric oxide synthase mRNA in endomyocardial biopsy specimens from patients with dilated cardiomyopathy

M Ohtsuki, T Nomura, S Morimoto, S Hiramitsu, A Uemura, S Kato, Y Kato, H Shiraishi, J Shimokubo, N Yamamoto, H Hishida

CLINICA CHIMICA ACTA, 353(1-2) 103-107, Mar, 2005
The effect of high glucose on NO and O-2(-) through endothelial GTPCH1 and NADPH oxidase

FD Qun, T Hayashi, ARJ Packiasamy, A Miyazaki, A Fukatsu, H Shiraishi, T Nomura, A Iguchi

LIFE SCIENCES, 75(26) 3185-3194, Nov, 2004
CGMP inhibits GTP cyclohydrolase I activity and biosynthesis of tetrahydrobiopterin in human umbilical vein emdothelial cells

Journal of Pharmacological Science, in press, 2003
CGMP inhibits GTP cyclohydrolase I activity and biosynthesis of tetrahydrobiopterin in human umbilical vein emdothelial cells

Journal of Pharmacological Science, in press, 2003
CAMP inhibits cytokine-induced biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells

Life Sciences, 70, 2187-2198, 2002
(6R)-5, 6, 7, 8 -Tetrahydro-L-monapterin from Escherichia coli, a novel natural unconjugated tetrahydropterin

Biological Chemistry, 383, 325-330, 2002
CAMP inhibits cytokine-induced biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells

Life Sciences, 70, 2187-2198, 2002
(6R)-5, 6, 7, 8 -Tetrahydro-L-monapterin from Escherichia coli, a novel natural unconjugated tetrahydropterin

Biological Chemistry, 383, 325-330, 2002
Catecholamines and serotonin are differently regulated by tetrahydrobiopterin

The Journal of Biological Chemistry, 276, 41150-41160, 2001
Catecholamines and serotonin are differently regulated by tetrahydrobiopterin

The Journal of Biological Chemistry, 276, 41150-41160, 2001
Identification of(6R)-5, 6, 7, 8-tetrahydro-D-monapterin C=(6R)-2-amino-5, 6, 7, 8-tetrahydro-6-[(1R, 2R)-1, 2, 3-trihydroxy propyl J-pteridin-4(3H)-one]as the native pteridine in tetrahymena pyriformis

Helvetica Chimica Acta, 84, 918-927, 2001
Effects of sylfhydryl reagents on nitric oxide release from a nitric oxide donor NOR3 in the presence of rat hepatocytes

Pharmacology & Toxicology, 87, 246-248, 2000
GTP Cyclohydrolase I from ┣DBTetrahymena(/)-┫DB ┣DBpyriformis(/)-┫DB : Cloning of cDNA and expression

Comparative Biochemistry and Physiology, 127, 65-73, 2000
Enzymes related to catecholamine biosynthesis in ┣DBTetrahymena(/)-┫DB ┣DBphriformis(/)-┫DB - Presence of GTP cyclohydrolase I -

Comparative Biochemistry and Phisiology, 120 753-760, 1998
Nitric oxide donor NOR 3 inhibits ketogenesis from oleate in isolated rat hepatocytes by a cyclic GMP-independent mechanism

T Nomura, M Ohtsuki, S Matsui, C Sumi-Ichinose, H Nomura, Y Hagino

PHARMACOLOGY & TOXICOLOGY, 82(1) 40-46, Jan, 1998
METABOLIC EFFECTS OF GLIBENCLAMIDE IN ISOLATED RAT HEPATOCYTES IN THE ABSENCE OF EXTRACELLULAR CA2+

T NOMURA, M OHTSUKI, T WATANABE, S HASEGAWA, S MATSUI, A TOMITA, C SUMIICHINOSE, H NOMURA, Y HAGINO

JAPANESE JOURNAL OF PHARMACOLOGY, 69(2) 173-176, Oct, 1995
Isolation of a full-length cDNA clone for human GTP cyclohydrolase I type 1 from pheochromocytoma

Journal of Neural Transmission, 1995
CLONING AND SEQUENCING OF CDNA-ENCODING MOUSE GTP CYCLOHYDROLASE-I

T NOMURA, H ICHINOSE, C SUMIICHINOSE, H NOMURA, Y HAGINO, K FUJITA, T NAGATSU

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 191(2) 523-527, Mar, 1993
α_1B-Adrenoceptor-mediated stimulation of Ca²⁺ mobilization and cAMP accumulation in isolated rat hepatocytes

European Journal of Pharmacology, 246,113-120, 1993
α₁-Adrenergic regulation of Ketogenesis in isolated rat hepatocytes.

Biochimica et Biophysica Acta, 1092, 1991
Effects of exogenous phospholipase enzymes, arachidonic acid and 1-oleoyl-2-acetyl-sn-glycerol on Ketogenesis in isolated rat hepatocytes.

Biochimica et Biophysica Acta, 1012, 1989
Effects of mepacrine on the oxidation of [1-¹⁴C]-oleate in isolated rat hepatocytes.

Japanese Journal of Pharmacology, 50, 1989
Effects of phorbol esters, A23187 and vasopressin on oleate metabolism in isolated rat hepatocytes.

Lipids, 22, 1987
Stimulation of fatty acid synthesis by 4β-phorbol-12-myristate-13-acetate in isolated rat hepatocytes.

Lipids, 21, 1986
Effects of vasopressin, angiotensin (]G0002[) and phenylephrine on hepatic Ketogenesis and fatty acid synthesis.

Japanese Journal of Pharmacology, 41, 1986
The effects of streptozotocin diabetes on tissue specific lipase activities in the rat.

Lipids, 19, 1984
Effects of octanoate and acetate upon hepatic glycolysis and lipogenesis.

Biochimica et Biophysica Acta, 754, 1983
The effects of fasting and streptozotocin diabetes on the triglyceride lipase activity of rat liver plasma membranes.

Lipids, 17, 1982
Comparison of the metabolic effects of chylimicrons and their remnants on isolated hepatocytes.

Archives of Biochemistry and Biophysics, 211, 1981

Books and Other Publications

3

シンプル薬理学

南江堂, 2008 (ISBN: 9784524250387)
シンプル薬理学改訂第3版

南江堂, 2004
α₁-Adrenergic-mediated increase in cytosolic Ca²⁺ and cyclic AMP in isolated rat hepatocytes

α-Adrenoceptors : Signal transduction, ionic channels and effector organs, 1992

Professional Memberships

6

Works

1

フィンランドにおけるエネルギー事情について

1990

Research Projects

4

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