研究者業績

野村隆英

ノムラタカヒデ (Takahide Nomura)

基本情報

所属: 藤田保健衛生大学医学部医学科薬理学教授

学位: 医学博士(名古屋大学)

J-GLOBAL ID: 200901093104640768
researchmap会員ID: 1000102461

研究キーワード

2

研究分野

1

ライフサイエンス / 薬理学 /

学歴

4

委員歴

2

受賞

1

1991年

坂幹雄賞

MISC

29

Suppressed expression of GTP cyclohydrolase I mRNA and accelerated expression of inducible nitric oxide synthase mRNA in endomyocardial biopsy specimens from patients with dilated cardiomyopathy

M Ohtsuki, T Nomura, S Morimoto, S Hiramitsu, A Uemura, S Kato, Y Kato, H Shiraishi, J Shimokubo, N Yamamoto, H Hishida

CLINICA CHIMICA ACTA 353(1-2) 103-107 2005年3月
The effect of high glucose on NO and O-2(-) through endothelial GTPCH1 and NADPH oxidase

FD Qun, T Hayashi, ARJ Packiasamy, A Miyazaki, A Fukatsu, H Shiraishi, T Nomura, A Iguchi

LIFE SCIENCES 75(26) 3185-3194 2004年11月
CGMP inhibits GTP cyclohydrolase I activity and biosynthesis of tetrahydrobiopterin in human umbilical vein emdothelial cells

Journal of Pharmacological Science in press 2003年
CGMP inhibits GTP cyclohydrolase I activity and biosynthesis of tetrahydrobiopterin in human umbilical vein emdothelial cells

Journal of Pharmacological Science in press 2003年
CAMP inhibits cytokine-induced biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells

Life Sciences 70, 2187-2198 2002年
(6R)-5, 6, 7, 8 -Tetrahydro-L-monapterin from Escherichia coli, a novel natural unconjugated tetrahydropterin

Biological Chemistry 383, 325-330 2002年
CAMP inhibits cytokine-induced biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells

Life Sciences 70, 2187-2198 2002年
(6R)-5, 6, 7, 8 -Tetrahydro-L-monapterin from Escherichia coli, a novel natural unconjugated tetrahydropterin

Biological Chemistry 383, 325-330 2002年
Catecholamines and serotonin are differently regulated by tetrahydrobiopterin

The Journal of Biological Chemistry 276, 41150-41160 2001年
Catecholamines and serotonin are differently regulated by tetrahydrobiopterin

The Journal of Biological Chemistry 276, 41150-41160 2001年
Identification of(6R)-5, 6, 7, 8-tetrahydro-D-monapterin C=(6R)-2-amino-5, 6, 7, 8-tetrahydro-6-[(1R, 2R)-1, 2, 3-trihydroxy propyl J-pteridin-4(3H)-one]as the native pteridine in tetrahymena pyriformis

Helvetica Chimica Acta 84, 918-927 2001年
Effects of sylfhydryl reagents on nitric oxide release from a nitric oxide donor NOR3 in the presence of rat hepatocytes

Pharmacology & Toxicology 87, 246-248 2000年
GTP Cyclohydrolase I from ┣DBTetrahymena(/)-┫DB ┣DBpyriformis(/)-┫DB : Cloning of cDNA and expression

Comparative Biochemistry and Physiology 127, 65-73 2000年
Enzymes related to catecholamine biosynthesis in ┣DBTetrahymena(/)-┫DB ┣DBphriformis(/)-┫DB - Presence of GTP cyclohydrolase I -

Comparative Biochemistry and Phisiology 120 753-760 1998年
Nitric oxide donor NOR 3 inhibits ketogenesis from oleate in isolated rat hepatocytes by a cyclic GMP-independent mechanism

T Nomura, M Ohtsuki, S Matsui, C Sumi-Ichinose, H Nomura, Y Hagino

PHARMACOLOGY & TOXICOLOGY 82(1) 40-46 1998年1月
METABOLIC EFFECTS OF GLIBENCLAMIDE IN ISOLATED RAT HEPATOCYTES IN THE ABSENCE OF EXTRACELLULAR CA2+

T NOMURA, M OHTSUKI, T WATANABE, S HASEGAWA, S MATSUI, A TOMITA, C SUMIICHINOSE, H NOMURA, Y HAGINO

JAPANESE JOURNAL OF PHARMACOLOGY 69(2) 173-176 1995年10月
Isolation of a full-length cDNA clone for human GTP cyclohydrolase I type 1 from pheochromocytoma

Journal of Neural Transmission 1995年
CLONING AND SEQUENCING OF CDNA-ENCODING MOUSE GTP CYCLOHYDROLASE-I

T NOMURA, H ICHINOSE, C SUMIICHINOSE, H NOMURA, Y HAGINO, K FUJITA, T NAGATSU

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 191(2) 523-527 1993年3月
α_1B-Adrenoceptor-mediated stimulation of Ca²⁺ mobilization and cAMP accumulation in isolated rat hepatocytes

European Journal of Pharmacology 246,113-120 1993年
α₁-Adrenergic regulation of Ketogenesis in isolated rat hepatocytes.

Biochimica et Biophysica Acta 1092 1991年
Effects of exogenous phospholipase enzymes, arachidonic acid and 1-oleoyl-2-acetyl-sn-glycerol on Ketogenesis in isolated rat hepatocytes.

Biochimica et Biophysica Acta 1012 1989年
Effects of mepacrine on the oxidation of [1-¹⁴C]-oleate in isolated rat hepatocytes.

Japanese Journal of Pharmacology 50 1989年
Effects of phorbol esters, A23187 and vasopressin on oleate metabolism in isolated rat hepatocytes.

Lipids 22 1987年
Stimulation of fatty acid synthesis by 4β-phorbol-12-myristate-13-acetate in isolated rat hepatocytes.

Lipids 21 1986年
Effects of vasopressin, angiotensin (]G0002[) and phenylephrine on hepatic Ketogenesis and fatty acid synthesis.

Japanese Journal of Pharmacology 41 1986年
The effects of streptozotocin diabetes on tissue specific lipase activities in the rat.

Lipids 19 1984年
Effects of octanoate and acetate upon hepatic glycolysis and lipogenesis.

Biochimica et Biophysica Acta 754 1983年
The effects of fasting and streptozotocin diabetes on the triglyceride lipase activity of rat liver plasma membranes.

Lipids 17 1982年
Comparison of the metabolic effects of chylimicrons and their remnants on isolated hepatocytes.

Archives of Biochemistry and Biophysics 211 1981年

書籍等出版物

3

シンプル薬理学

南江堂 2008年 (ISBN: 9784524250387)
シンプル薬理学改訂第3版

南江堂 2004年
α₁-Adrenergic-mediated increase in cytosolic Ca²⁺ and cyclic AMP in isolated rat hepatocytes

α-Adrenoceptors : Signal transduction, ionic channels and effector organs 1992年

所属学協会

6

もっとみる

Works(作品等)

1

フィンランドにおけるエネルギー事情について

1990年

共同研究・競争的資金等の研究課題

4

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