研究者業績

太田好次

オオタヨシジ (Yoshiji Ohta)

基本情報

所属: 藤田保健衛生大学医学部一般教育化学教授

学位: 博士(医学)(藤田保健衛生大学)
修士(薬学)(岐阜薬科大学)

J-GLOBAL ID: 200901088910182423
researchmap会員ID: 1000102491

研究分野

2

経歴

8

1993年 - 1999年

藤田保健衛生大学医学部助教授
1993年 - 1999年

藤田医科大学
1984年 - 1993年

藤田学園保健衛生大学医学部講師
1984年 - 1993年

Fujita-Gakuen Health University School of Medicine, Assitant Professor
1973年 - 1984年

名古屋保健衛生大学医学部助手

もっとみる

学歴

4

委員歴

5

MISC

176

Preventive effect of teprenone on acute gastric mucosal lesion progression in compound 48/80-treated rats（共著）

European Journal of Pharmacology 487(1-3) 223-232 2004年3月
Preventive effect of teprenone on acute gastric mucosal lesion progression in compound 48/80-treated rats

Y Ohta, T Kobayashi, K Inui, J Yoshino, A Kitagawa, S Nakazawa

EUROPEAN JOURNAL OF PHARMACOLOGY 487(1-3) 223-232 2004年3月
Short-term ascorbic acid deficiency induced oxidative stress in the retinas of young guinea pigs（共著）

Journal of Biomedical Science 11(2) 172-178 2004年
Melatonin prevents disruption of hepatic reactive oxygen species metabolism in rats treated with carbon tetrachloride.（共著）

Journal of Pineal Research 36(1), 10-17 2004年
Short-term ascorbic acid deficiency induced oxidative stress in the retinas of young guinea pigs

Y Ohta, T Okubo, T Niwa, T Yamasaki, M Horiguchi

JOURNAL OF BIOMEDICAL SCIENCE 11(2) 172-178 2004年
Melatonin prevents disruption of hepatic reactive oxygen species metabolism in rats treated with carbon tetrachloride.‘jointly worked’

Journal of Pineal Research 36(1) 10-17 2004年
Relationship between obesity and serum markers of oxidative stress and inflammation in Japanese residents "jointly worked"

Asia Pacific Journal of Cancer Prevention 14(3) 256-266 2003年
Protective effect of co‐administered superoxide dismutase and catalase against stress‐induced gastric mucosal lesions. "jointly worked"

Clinical and Experimental Pharmacology and Physiology 30(8) 545-550 2003年
Preventive effect of melatonin on the progression of α-naphthylisothiocyanate‐induced acute liver injury in rats. "jointly worked"

Journal of Pineal Research 34(3) 185-193 2003年
Melatonin exerts a therapeutic effect on cholestatic liver injury in rats with bile duct ligation. "jointly worked"

Journal of Pineal Research 34(2) 119-126 2003年
Relationship between obesity and serum markers of oxidative stress and inflammation in Japanese residents "jointly worked"

Asia Pacific Journal of Cancer Prevention 14(3) 256-266 2003年
Protective effect of co‐administered superoxide dismutase and catalase against stress‐induced gastric mucosal lesions. "jointly worked"

Clinical and Experimental Pharmacology and Physiology 30(8) 545-550 2003年
Preventive effect of melatonin on the progression of α-naphthylisothiocyanate‐induced acute liver injury in rats. 'jointly worked'

Journal of Pineal Research 34(3) 185-193 2003年
Melatonin exerts a therapeutic effect on cholestatic liver injury in rats with bile duct ligation. 'jointly worked'

Journal of Pineal Research 34(2) 119-126 2003年
Protective effect of omeprazole against acute gastric mucosal lesions induced by compound 48/80, a mast cell degranulator, in rats.（共著）

Pharmacological Research 46(1) 75-84 2002年7月
Protective effect of omeprazole against acute gastric mucosal lesions induced by compound 48/80, a mast cell degranulator, in rats

T Kobayashi, Y Ohta, K Inui, J Yoshino, S Nakazawa

PHARMACOLOGICAL RESEARCH 46(1) 75-84 2002年7月
Evaluation of anti-lipid peroxidative action of propolis ethanol extract（共著）

Phytotherapy Research 16(4) 340-347 2002年6月
Protective effect of ebselen, a seleno organic compound, against the progression of acute gastric mucosal lesions induces by compound 48/80, a mast cell degranulator, in rats. "jointly worked"

OHTA Y, KOBAYASHI T, INUI K, NAKAZAWA S, YOSHINO J

Japanese Journal of Pharmacol. ogy 90(4) 295-303 2002年
L-Tryptophan administration promotes the reversion of pre-established chronic liver injury in rats treated with carbon tetrachloride.（共著）

Journal of Nutritional Biochemitry 13(9), 550-559 2002年
Partial reversal of methylprednisolone-induced opacity in isolated rat lenses.（共著）

Ophthalmic Research 34(3), 128-134 2002年
Prolonged marginal ascorbic acid deficiency induces oxidative stress in retina of guinea pigs.（共著）

International Journal for Vitamin and Nutrition Research 72(1), 63-70 2002年
L-Arginine protects against stress-induced gastric mucosal lesions by preserving gastric mucus.（共著）

Clinical and Experimental Pharmacology and Physiology 29(1-2), 32-38 2002年
Protective effect of ebselen, a seleno organic compound, against the progression of acute gastric mucosal lesions induces by compound 48/80, a mast cell degranulator, in rats. "jointly worked"

Japanese Journal of Pharmacology 90(4) 295-303 2002年
L-Tryptophan administration promotes the reversion of pre-established chronic liver injury in rats treated with carbon tetrachloride. "jointly worked"

Journal of Nutritional Biochemitry 13(9), 550-559 2002年
Evaluation of anti-lipid peroxidative action of propolis ethanol extract "jointly worked"

Phytotherapy Research 16(4), 340-347 2002年
Partial reversal of methylprednisolone-induced opacity in isolated rat lenses. "jointly worked"

Ophthalmic Research 34(3), 128-134 2002年
Prolonged marginal ascorbic acid deficiency induces oxidative stress in retina of guinea pigs. "jointly worked"

International Journal for Vitamin and Nutrition Research 72(1), 63-70 2002年
L-Arginine protects against stress-induced gastric mucosal lesions by preserving gastric mucus. "jointly worked"

Clinical and Experimental Pharmacology and Physiology 29(1-2), 32-38 2002年
Protective effect of L-arginine against stress-induced gastric mucosal lesions in rats. Its relation to nitric oxide-mediated inhibition of neutrophil infiltration.（共著）

Pharmacological Research 43(6) 535-541 2001年6月
Protective effect of L-arginine against stress-induced gastric mucosal lesions in rats and its relation to nitric oxide-mediated inhibition of neutrophil infiltration

Y Ohta, K Nishida

PHARMACOLOGICAL RESEARCH 43(6) 535-541 2001年6月
Inhibitory action of Oren-gedoku-to extract on enzymatic lipid peroxidation in rat liver microsomes.（共著）

Biological and Pharmaceutical Bulletin 24(10), 1165-1170 2001年
Effect of melatonin on changes in hepatic antioxidant enzyme activities in rats treated with α-naphthylisothiocyanate.（共著）

Journal of Pineal Research 31(4), 370-377 2001年
Preventive effect of ebselen on acute gastric mucosa lesion development in rats treated with compound 48/80.（共著）

European Jouranl of Pharmacology 414(2-3), 271-279 2001年
Effect of prolonged marginal ascorbic acid deficiency on letincular levels of antioxidants and lipid peroxide in guinea pigs.（共著）

International Journal for Vitamin and Nutrition Research 71(2), 103-109 2001年
Teprenone ptomotes the healing of acetic acid-induced chronic gastric ulcers in rats by inhibiting neutrophil infilitration and lipid peroixdation in ulcerated gastric tissues.（共著）

Pharmacological Research 43(1) 23-30 2001年1月
Inhibitory action of Oren-gedoku-to extract on enzymatic lipid peroxidation in rat liver microsomes. "jointly worked"

Biological and Pharmaceutical Bulletin 24(10), 1165-1170 2001年
Effect of melatonin on changes in hepatic antioxidant enzyme activities in rats treated with α-naphthylisothiocyanate. "jointly worked"

Journal of Pineal Research 31(4), 370-377 2001年
Preventive effect of ebselen on acute gastric mucosa lesion development in rats treated with compound 48/80. "jointly worked"

European Jouranl of Pharmacology 414(2-3), 271-279 2001年
Effect of prolonged marginal ascorbic acid deficiency on letincular levels of antioxidants and lipid peroxide in guinea pigs. "jointly worked"

International Journal for Vitamin and Nutrition Research 71(2), 103-109 2001年
Teprenone ptomotes the healing of acetic acid-induced chronic gastric ulcers in rats by inhibiting neutrophil infilitration and lipid peroixdation in ulcerated gastric tissues. "jointly worked"

Pharmacological Research 43(1), 23-30 2001年
Opacificaiton of isolated rat lenses intoxicated with diethylmaleate. Releation to lens membrane dysfunction.（共著）

In Vitro Molecular Toxicology 13(4), 223-236 2000年
Preventive effect of topical vitamin E-containing liposome instillation on cataract progression in 12-month-old rats fed a 25% galactose diet.（共著）

Journal of Ocular Pharmacology and Therapeutics 16(4), 323-335 2000年
Protective effect of melatonin against α-naphtbylisothiocyanate-induced liver injury in rats.（共著）

Journal of Pineal Research 29(1), 15-23 2000年
Therapeutic effect of melatonin on carbon tetrachloride-induced acute liver injury in rats.（共著）

Journal of Pineal Research 28(1), 119-126 2000年
Opacificaiton of isolated rat lenses intoxicated with diethylmaleate. Releation to lens membrane dysfunction. "jointly worked"

In Vitro Molecular Toxicology 13(4), 223-236 2000年
Preventive effect of topical vitamin E-containing liposome instillation on cataract progression in 12-month-old rats fed a 25% galactose diet. "jointly worked"

Journal of Ocular Pharmacology and Therapeutics 16(4), 323-335 2000年
Protective effect of melatonin against α-naphtbylisothiocyanate-induced liver injury in rats. "jointly worked"

Journal of Pineal Research 29(1), 15-23 2000年
Therapeutic effect of melatonin on carbon tetrachloride-induced acute liver injury in rats. "jointly worked"

Journal of Pineal Research 28(1), 119-126 2000年
Change in hepatic antioxidant defense system with liver injury development in rats with a single α-naphthylisothiocyanate intoxication.（共著）

Toxicology 139(3), 265-275 1999年
Preventive effect of Oren-gedoku-to (Huanglian-Jie-Du-Tang) extract on the development of stress-induced acute gastric mucosal lesions in rats.（共著）

Journal of Ethnopharmacology 67(3), 377-384 1999年

所属学協会

15

もっとみる

Works(作品等)

8

急性胃粘膜障害に対するプラウノトールの治療効果に関する研究

2001年 - 2002年
Therapeutic effect of plaunotol on acute gastric mucosal lesions

2001年 - 2002年
柴胡桂枝湯エキス剤の肝・胆道疾患に対する抑制効果

1998年 - 1999年
Preventive effect of Saiko-Keishi-to extract on hepatobilirary injury

1998年 - 1999年
テプレノンの胃粘液分泌機序、好中球およびNOとの関連からの検討

1996年

もっとみる

共同研究・競争的資金等の研究課題

6

L-トリプトファンの肝細胞への輸送とその調節

1985年
Transport of L-tryptophan into hepatocytes and its regulation

1985年
白内障の成因と抗白内障薬の開発

1980年
Causative factors of cataract and development of anti-cataract drug

1980年
各種疾患とフリーラジカルとの関連性

1977年

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