研究者業績

渡邊 祐介

ワタナベ ユウスケ  (Yusuke Watanabe)

基本情報

所属
北海道大学 北海道大学病院臨床研究開発センター 特任講師
藤田医科大学 先端ロボット・内視鏡手術学講座 准教授
学位
医学博士(北海道大学大学院)

J-GLOBAL ID
201801002924758520
researchmap会員ID
B000333345

学歴

 1

論文

 84
  • Fumihiko Hattanda, Yusuke Watanabe, Yusuke Sakuhara, Shun Takenaka, Tauro Kawamura, Naoko Matsuoka, Daigo Nakazawa, Yoichi M Ito, Hiroshi Kondo, Shin Goto, Yoshitaka Isaka, Ken Tsuchiya, Toshio Mochizuki, Satoru Muto, Haruna Kawano, Tatsuya Atsumi, Saori Nishio
    Clinical and experimental nephrology 2025年7月23日  
    BACKGROUND: Accurate liver volume measurement is crucial for evaluating liver cyst severity and treatment efficacy in polycystic liver disease (PLD). Previous methods are impractical because they are time-consuming and labor-intensive. This study developed and validated two simplified CT imaging methods: the Bi-axial Simplified Measurement Method (BASiM) and the Quadri-dimensional Simplified Measurement Method (QDSiM). METHODS: This retrospective study analyzed 76 CT images from 26 PLD patients who underwent transarterial hepatic artery embolization (TAE). Images were obtained before TAE, 24 weeks after TAE and during the follow-up period. Liver volumes were measured using semi-automatic volumetry, BASiM, and QDSiM. BASiM calculates liver volume based on cranio-caudal, anterior-posterior, and medial-lateral dimensions, while QDSiM divides the liver into left- and right-side sections. This study assessed inter-assessor reliability, measurement accuracy, volume change rate, and calculation times. RESULTS: BASiM demonstrated strong inter-assessor reliability (intraclass correlation coefficient [ICC]: 0.991, 95% confidence interval [CI] 0.986-0.994) superior to QDSiM (ICC: 0.851, 95% CI 0.205-0.949). Calibrated liver volumes using BASiM and QDSiM were consistent with semi-automatic volumetry (ICC: 0.924, 95% CI 0.858 to 0.957, and ICC: 0.934, 95% CI 0.806-0.970, respectively). BASiM showed better alignment with volume changes (ICC: 0.835, 95% CI 0.537-0.927) compared to QDSiM (ICC: 0.607, 95% CI 0.203-0.800) and required less measurement time (61 ± 4 s vs. 107 ± 9 s, p < 0.01). CONCLUSION: BASiM provided superior reliability, accuracy, and efficiency for liver volume measurement in PLD, thus useful for the clinical management of PLD.
  • Ayaka Ito, Masaya Nakauchi, Masahiro Fujita, Yusuke Umeki, Kazumitsu Suzuki, Akiko Serizawa, Shingo Akimoto, Yusuke Watanabe, Tsuyoshi Tanaka, Susumu Shibasaki, Kazuki Inaba, Ichiro Uyama, Koichi Suda
    Langenbeck's archives of surgery 410(1) 110-110 2025年3月29日  
    PURPOSE: Reduced-port surgery has been utilized in gastric cancer surgery but is not predominantly used due to its high technical difficulty. A new single-port surgical robot named da Vinci™ SP System (DVSP) was launched and eventually approved for clinical use in Japan in November 2022. We initiated robotic gastrectomy for gastric cancer using DVSP in March 2023. Here, we report our initial experiences and assessments of the feasibility and safety of robotic gastrectomy for gastric cancer using DVSP. METHODS: This single-center retrospective study included 20 patients with gastric cancer who underwent robotic gastrectomy with DVSP from March 2023 to April 2024. The primary endpoint was the postoperative complication rate within 30 days postoperatively. Secondary endpoints were surgical outcomes, including intraoperative adverse events, operative time, blood loss, and the number of dissected nodes. RESULTS: Of the 20 patients, 6 (30.0%) were male. The median age was 74 years. Tumors in the middle to lower stomach were observed in 20 patients (100.0%), including 18 (90.0%) and 2 (10.0%) with clinical stages I and II diseases, respectively. All patients underwent distal gastrectomy. The postoperative complications of Clavien-Dindo grade ≥ II occurred in 3 (15%) patients. Intraoperative adverse events, including conversion to other approaches, were not observed. All patients underwent R0 resection. The median operative and console times were 289 and 240 min, respectively. The median blood loss was 11 mL with 50 dissected nodes. CONCLUSION: This study revealed the safe performance of robotic distal gastrectomy with standard lymphadenectomy for clinical stage I/II gastric cancer using DVSP.
  • Kotoe Kiriyama, Yo Kurashima, Saseem Poudel, Yusuke Watanabe, Yoichi M Ito, Satoshi Hirano
    Surgery 180 109136-109136 2025年1月21日  
    BACKGROUND: Telesimulation has been shown to be effective for teaching simple surgical techniques; however, its usefulness for teaching advanced skills remains unclear. The aim of this randomized controlled trial was to investigate the impact of a telesimulation program on training for laparoscopic inguinal hernia repair. METHODS: Novice trainees were randomly assigned to the intervention group or control group using a permuted block design. Intervention group participants received a 1-hour didactic telelecture and three 1-hour telesimulation sessions with a hernia specialist, whereas control group participants engaged in self-directed training using the same simulator and materials. Trainees' procedural videos, recorded before and after training, were assessed using the transabdominal preperitoneal checklist and the Global Operative Assessment of Laparoscopic Skills-Groin Hernia. Pre- and post-training tests were performed to evaluate knowledge of inguinal hernias and self-confidence in transabdominal preperitoneal procedures. RESULTS: Forty-three participants from 16 institutions in Japan were enrolled, with 22 and 19 in the intervention group and control group, respectively, completing the final analysis. Median post-test transabdominal preperitoneal checklist scores were 16 (interquartile range: 15-18.5) in the intervention group and 11 (interquartile range: 8.5-14.5) in the control group; intervention group participants significantly outperformed their counterparts (P < .001). However, comparison of pre- and post-test scores showed skill improvements in both groups (P < .001). Both groups also showed increased knowledge and confidence. CONCLUSION: The telesimulation program effectively enhanced the surgical skills of novice trainees in learning laparoscopic inguinal hernia repair, demonstrating superiority over self-directed learning.
  • Masahiro Fujita, Masaya Nakauchi, Masamoto Iida, Keisuke Koide, Seiji Inoue, Ai Goto, Kazumitsu Suzuki, Yusuke Umeki, Akiko Serizawa, Shingo Akimoto, Yusuke Watanabe, Tsuyoshi Tanaka, Susumu Shibasaki, Kazuki Inaba, Ichiro Uyama, Koichi Suda
    Asian journal of endoscopic surgery 17(3) e13326 2024年7月  査読有り
    Concurrent direct and indirect inguinal, femoral, and obturator hernias are rare. This case report describes a rare case treated using the laparoscopic approach. A 68-year-old female patient presented with a moving left inguinal lump and pain. Physical examination and abdominal computed tomography scan revealed the coexistence of a left inguinal hernia or Nuck canal hydrocele and a left femoral hernia. The patient underwent laparoscopic transabdominal preperitoneal repair, and all four orifices were covered with one mesh. The patient was discharged on the second postoperative day without any complications. The concurrent presence of four hernias on the same side is rare and has not been previously reported. The laparoscopic approach is useful in such cases because it allows visualization of multiple hernia orifices from the intra-abdominal cavity.
  • Dai Miyazaki, Toshiaki Shichinohe, Yusuke Watanabe, Kimitaka Tanaka, Yoshitsugu Nakanishi, Toshimichi Asano, Yo Kurashima, Yuma Ebihara, Soichi Murakami, Satoshi Hirano
    Annals of gastroenterological surgery 8(4) 660-667 2024年7月  査読有り
    PURPOSE: Operations for malignant diseases of the bile duct, pancreas, and esophagus are the most invasive gastroenterological surgeries. The frequency of complications after these surgeries is high, which affects the postoperative course and mortality. In patients who undergo these types of surgeries, continuous monitoring of the perioperative central venous oxygen saturation (ScvO2) is possible via a central venous catheter. We aimed to investigate the relationship between continuously monitored perioperative ScvO2 values and postoperative complications. METHODS: The medical records of 115 patients who underwent highly invasive gastroenterological surgeries and ScvO2 monitoring from April 2012 to March 2014 were analyzed. Sixty patients met the inclusion criteria, and their ScvO2 levels were continuously monitored perioperatively. The relationship between ScvO2 levels and major postoperative complications, defined as Clavien-Dindo grade ≥ III, was examined using uni- and multivariate analysis. RESULTS: Thirty patients developed major postoperative complications. The adequate cut-off value derived from receiver operating curves of the postoperative average ScvO2 levels for predicting major complications was 75%. Multivariate analysis revealed that low average postoperative ScvO2 levels (p = 0.016) and blood loss ≥ 1000 mL (p = 0.039) were significant predictors of major postoperative complications. CONCLUSIONS: Low perioperative ScvO2 values were associated with an increased risk of major postoperative complications. Continuous ScvO2 monitoring will help prevent postoperative complications.
  • Seiji Inoue, Masaya Nakauchi, Yusuke Umeki, Kazumitsu Suzuki, Akiko Serizawa, Shingo Akimoto, Yusuke Watanabe, Tsuyoshi Tanaka, Susumu Shibasaki, Kazuki Inaba, Ichiro Uyama, Koichi Suda
    Surgical endoscopy 38(3) 1626-1636 2024年3月  査読有り
    BACKGROUND: Although the da Vinci™ Surgical System is the most predominantly used surgical robot worldwide, other surgical robots are being developed. The Japanese surgical robot hinotori™ Surgical Robot System was launched and approved for clinical use in Japan in November 2022. We performed the first robotic gastrectomy for gastric cancer using hinotori in the world. Here, we report our initial experience and evaluation of the feasibility and safety of robotic gastrectomy for gastric cancer using hinotori. METHODS: A single-institution retrospective study was conducted. Between November 2022 and October 2023, 24 patients with gastric cancer underwent robotic gastrectomy with hinotori. Five ports, including one for an assistant, were placed in the upper abdomen, and gastric resection with standard lymphadenectomy and intracorporeal reconstruction were performed. The primary endpoint was the postoperative complication rate within 30 days after surgery. The secondary outcomes were surgical outcomes, including intraoperative adverse events, operative time, blood loss, and the number of dissected nodes. RESULTS: Of the 24 patients, 16 (66.7%) were male. The median age and body mass index were 73.5 years and 22.9 kg/m2, respectively. Twenty-three patients (95.8%) had tumors in the middle to lower stomach. Sixteen (66.7%) and seven (29.2%) patients had clinical stage I and II diseases, respectively. Twenty-three (95.8%) patients underwent distal gastrectomy. No patient had postoperative complications of Clavien-Dindo classification IIIa or higher, whereas two (8.3%) had the grade II complications (enteritis and pneumonia). No intraoperative adverse events, including conversion to other approaches, were observed. All patients received R0 resection. The median operative and console times were 400 and 305 min, respectively. The median blood loss was 14.5 mL, and the number of lymph nodes dissected was 51.5. CONCLUSIONS: This study found that robotic gastrectomy with standard lymphadenectomy for gastric cancer using hinotori can be safely performed.
  • Akihiro Kondo, Masato Tamate, Yuichi Nishihara, Yusuke Watanabe
    Surgical endoscopy 38(1) 368-376 2024年1月  査読有り責任著者
    BACKGROUND: Several well-trained expert instructors who completed the "Train-The-Trainer (TTT)" course are required to disseminate the safe use of surgical energy devices, which can be learned through the Fundamental Use of Surgical Energy (FUSE) program. This study aimed to explore whether the hybrid FUSE TTT course is feasible and effective, which can improve teaching skills of surgical energy. METHODS: The hybrid TTT course, which was designed to train FUSE-certified personnel as instructors, comprised three virtual sessions spread over 5 h in total and a 1-day in-person training, followed by a 100-min FUSE electrosurgery hands-on workshop in practice as an instructor. The participants reported on self-confidence regarding knowledge of various energy devices or adverse events before, immediately after, and 6 months after the course. Participants and experienced FUSE instructors assessed the trainees' presentation skills at the beginning of the in-person training and after the hands-on workshop. The primary outcomes were the feasibility and completion rate of the entire course. RESULTS: Seventeen participants completed the entire couse; most (94%) were satisfied with the course. Self-confidence in knowledge about various contents improved significantly: the fundamentals of electrosurgery (post, p < 0.001; 6 months, p = 0.01), mechanism and prevention of adverse events (post, p = 0.001; 6 months, p = 0.04), monopolar instruments (post, p = 0.002; 6 months, p = 0.01), bipolar instruments (post, p = 0.01; 6 months, p = 0.06), and integration with other medical devices (post, p = 0.006; 6 months, p = 0.02). The presentation skill index scores of self- and peer assessments improved after the in-person training (self-assessment [pre 44 vs. post 56, p < 0.001], peer assessment [pre 39 vs. post 68, p < 0.001]). CONCLUSIONS: The hybrid TTT course can provide FUSE-certified personnel with an improved self-confidence concerning knowledge of surgical energy and improve their presentation skills with midterm retention. This can help build trainees' self-confidence as instructors.
  • Yusuke Watanabe, Keiko Yamamoto, Zijian Yang, Haruna Tsuchibora, Masakazu Fujii, Masayoshi Ono, Shoko Ono, Takayuki Kurokawa, Naoya Sakamoto
    Surgical Endoscopy 2023年7月19日  査読有り
  • Ghada Enani, Melina Vassiliou, Pepa Kaneva, Yusuke Watanabe, Amani Munshi
    Journal of surgical education 80(7) 1005-1011 2023年7月  査読有り
    OBJECTIVES: Laparoscopic suturing (LS) is a challenging laparoscopic skill to teach. Its complexity and nuances are not modeled or measured in current simulation and assessment platforms.The script concordance test (SCT) is used to assess clinical reasoning.The purpose of this study is to provide evidence for validity of this novel SCT based online assessment for LS skills. DESIGN: We designed a video-based online SCT for LS using a cognitive task analysis and expert panelists.The CTA yielded 4 LS domains: needle handling (NH), tissue handling (TH), knot tying techniques (KT) and operative ergonomics (OE). Five-point scales with anchoring descriptors from -2 to +2 were used. Scoring was based on a modified SCT methodology. SETTING AND PARTICIPANTS: The test was administrated to 37 subjects (18 experts and 19 novices). There was no time limit given. A different expert group from the minimal invasive surgery (MIS) panelist were recruited. Experts were defined as surgeons and fellows with LS experience of >25 cases annually. Validity was assessed by comparing SCT scores of experienced and inexperienced surgeons. Cronbach's alpha was used to assess the internal consistency of the test. RESULTS: The survey started off with 47 questions in each of the following domains: 13 NH, 4 TH, 20 KT and 10 OE. Thirty-seven surgeons (18 experts and 19 inexperienced surgeons). Questions that demonstrated a large discrepancy among experts and panelists with a weighted score difference more than 40 were discarded (n = 20). One question was discarded because it received a 100% score from all participants. This yielded 26 remaining questions in the following domains: 8 NH, 2 TH, 11 KT and 5 OE. The test reliability level (Cronbach a) was 0.80. The mean score was 72 ± 9% and 63 ± 15% (p = 0.02) for experts and inexperienced surgeons, respectively. The mean time to complete the test was 21 minutes. CONCLUSION: This study provides validity evidence for a novel intraoperative LS assessment. The variability of responses between experts and panelists suggests that SCT may capture the clinical differences/surgeon preferences in performing LS intraoperatively.
  • Kenichi Mizunuma, Yo Kurashima, Saseem Poudel, Yusuke Watanabe, Takehiro Noji, Toru Nakamura, Keisuke Okamura, Toshiaki Shichinohe, Satoshi Hirano
    Surgery 2023年3月30日  査読有り
    BACKGROUND: Pancreatoduodenectomy, an advanced surgical procedure with a high complication rate, requires surgical skill in performing pancreaticojejunostomy, which correlates with operative outcomes. We aimed to analyze the correlation between pancreaticojejunostomy assessment conducted in a simulator environment and the operating room and patient clinical outcomes. METHODS: We recruited 30 surgeons (with different experience levels in pancreatoduodenectomy) from 11 institutes. Three trained blinded raters assessed the videos of the pancreaticojejunostomy procedure performed in the operating room using a simulator according to an objective structured assessment of technical skill and a newly developed pancreaticojejunostomy assessment scale. The correlations between the assessment score of the pancreaticojejunostomy performed in the operating room and using the simulator and between each assessment score and patient outcomes were calculated. The participants were also surveyed regarding various aspects of the simulator as a training tool. RESULTS: There was no correlation between the average score of the pancreaticojejunostomy performed in the operating room and that in the simulator environment (r = 0.047). Pancreaticojejunostomy scores using the simulator were significantly lower in patients with postoperative pancreatic fistula than in those without postoperative pancreatic fistula (P = .05). Multivariate analysis showed that pancreaticojejunostomy assessment scores were independent factors in postoperative pancreatic fistula (P = .09). The participants highly rated the simulator and considered that it had the potential to be used for training. CONCLUSION: There was no correlation between pancreaticojejunostomy surgical performance in the operating room and the simulation environment. Surgical skills evaluated in the simulation setting could predict patient surgical outcomes.
  • Pietro Mascagni, Deepak Alapatt, Luca Sestini, Maria S Altieri, Amin Madani, Yusuke Watanabe, Adnan Alseidi, Jay A Redan, Sergio Alfieri, Guido Costamagna, Ivo Boškoski, Nicolas Padoy, Daniel A Hashimoto
    NPJ digital medicine 5(1) 163-163 2022年10月28日  招待有り
    Hundreds of millions of operations are performed worldwide each year, and the rising uptake in minimally invasive surgery has enabled fiber optic cameras and robots to become both important tools to conduct surgery and sensors from which to capture information about surgery. Computer vision (CV), the application of algorithms to analyze and interpret visual data, has become a critical technology through which to study the intraoperative phase of care with the goals of augmenting surgeons' decision-making processes, supporting safer surgery, and expanding access to surgical care. While much work has been performed on potential use cases, there are currently no CV tools widely used for diagnostic or therapeutic applications in surgery. Using laparoscopic cholecystectomy as an example, we reviewed current CV techniques that have been applied to minimally invasive surgery and their clinical applications. Finally, we discuss the challenges and obstacles that remain to be overcome for broader implementation and adoption of CV in surgery.
  • Kotoe Kiriyama, Saseem Poudel, Yo Kurashima, Yusuke Watanabe, Yoshihiro Murakami, Kyosuke Miyazaki, Yo Kawarada, Satoshi Hirano
    Global Surgical Education - Journal of the Association for Surgical Education 1(1) 2022年10月20日  査読有り
  • Takahiro Igaki, Shin Takenaka, Yusuke Watanabe, Shigehiro Kojima, Kei Nakajima, Yuya Takabe, Daichi Kitaguchi, Nobuyoshi Takeshita, Masafumi Inomata, Hiroya Kuroyanagi, Yusuke Kinugasa, Masaaki Ito
    Surgical endoscopy 2022年9月12日  査読有り
    BACKGROUND: Prioritizing patient health is essential, and given the risk of mortality, surgical techniques should be objectively evaluated. However, there is no comprehensive cross-disciplinary system that evaluates skills across all aspects among surgeons of varying levels. Therefore, this study aimed to uncover universal surgical competencies by decomposing and reconstructing specific descriptions in operative performance assessment tools, as the basis of building automated evaluation system using computer vision and machine learning-based analysis. METHODS: The study participants were primarily expert surgeons in the gastrointestinal surgery field and the methodology comprised data collection, thematic analysis, and validation. For the data collection, participants identified global operative performance assessment tools according to detailed inclusion and exclusion criteria. Thereafter, thematic analysis was used to conduct detailed analyses of the descriptions in the tools where specific rules were coded, integrated, and discussed to obtain high-level concepts, namely, "Skill meta-competencies." "Skill meta-competencies" was recategorized for data validation and reliability assurance. Nine assessment tools were selected based on participant criteria. RESULTS: In total, 189 types of skill performances were extracted from the nine tool descriptions and organized into the following five competencies: (1) Tissue handling, (2) Psychomotor skill, (3) Efficiency, (4) Dissection quality, and (5) Exposure quality. The evolutionary importance of these competences' different evaluation targets and purpose over time were assessed; the results showed relatively high reliability, indicating that the categorization was reproducible. The inclusion of basic (tissue handling, psychomotor skill, and efficiency) and advanced (dissection quality and exposure quality) skills in these competencies enhanced the tools' comprehensiveness. CONCLUSIONS: The competencies identified to help surgeons formalize and implement tacit knowledge of operative performance are highly reproducible. These results can be used to form the basis of an automated skill evaluation system and help surgeons improve the provision of care and training, consequently, improving patient prognosis.
  • Akihiro Kondo, Yuichi Nishihara, Miho Sato, Elif Bilgic, Yusuke Watanabe
    Surgical Endoscopy 2022年8月3日  査読有り最終著者責任著者
    BACKGROUND: The Fundamental Use of Surgical Energy (FUSE) program was established to educate surgeons and trainees to promote awareness and behaviors for the safe use of surgical energy devices. Despite its implementation, the impact of FUSE certification on surgeons' behavior and safety awareness regarding practice of energy devices remains unclear. This study aimed to identify the perceived impact of FUSE certification on surgeons' behavior and awareness regarding the safe use of surgical energy devices. METHODS: We performed a descriptive cross-sectional survey study, using non probabilistic purposive sampling, and distributed 22-item web-based questionnaires among all 59 FUSE-certified surgeons in Japan, excluding operating room nurses and medical students. The questionnaire items covered demographics, surgical techniques using various energy devices, changes in behavior and safety awareness, communication with colleagues about surgical energy devices, and educational activities related to energy devices. RESULTS: Fifty-seven participants completed the questionnaire (response rate 96.6%). Most surgeons (91.3%) could apply material learned from the FUSE program in practice, especially material related to monopolar electrosurgery. Fifty-six surgeons (98.3%) reported increased awareness of surgical safety, and 35 (61.5%) reported increased communication with operating room personnel about the safe use of energy devices. Moreover, 56 participants (98.3%) indicated a need for systematic education in surgical energy, with participants recommending fellows (94.7% of participants specified that fellows should participate in further education), residents (75.4%), and attending surgeons (63.2%) as the target recipients of this training. Conclusions After FUSE certification, not only did surgeons' knowledge increase, but their energy-related surgical techniques in practice also improved. Furthermore, FUSE-certified surgeons felt that they were more aware of surgical-energy safety and were dedicated to its promotion.
  • Elif Bilgic, Allan Okrainec, John Paige, Saba Balvardi, Sofia Valanci, Caterina Masino, Pepa Kaneva, Mohammed Alabri, Katherine M. McKendy, Yusuke Watanabe, Melina C. Vassiliou, Gerald M. Fried
    Surgical Endoscopy 2022年6月21日  査読有り
  • 水沼 謙一, 倉島 庸, サシーム・パウデル, 渡邊 祐介, 田中 公貴, 中西 善嗣, 浅野 賢道, 野路 武寛, 海老原 裕磨, 村上 壮一, 中村 透, 土川 貴裕, 七戸 俊明, 平野 聡
    日本臨床外科学会雑誌 83(3) 599-599 2022年3月  
  • Yuma Ebihara, Yo Kurashima, Yusuke Watanabe, Kimitaka Tanaka, Aya Matsui, Yoshitsugu Nakanishi, Toshimichi Asano, Takehiro Noji, Toru Nakamura, Soichi Murakami, Takahiro Tsuchikawa, Keisuke Okamura, Yoshihiro Murakami, Katsuhiko Murakawa, Fumitaka Nakamura, Takayuki Morita, Shunichi Okushiba, Toshiaki Shichinohe, Satoshi Hirano
    Langenbeck's archives of surgery 407(4) 1461-1469 2022年1月26日  査読有り
    PURPOSE: This study evaluated the short-term outcomes and prognosis after laparoscopic total gastrectomy (LTG) in elderly patients aged ≥ 80 years in a multicenter retrospective cohort study using propensity score matching. METHODS: We retrospectively enrolled 440 patients who underwent curative LTG for gastric cancer at six institutions between January 2004 and December 2018. Patients were categorized into an elderly patient group (EG; age ≥ 80 years) and non-elderly patient group (non-EG; age < 80 years). Patients were matched using the following propensity score covariates: sex, body mass index, American Society of Anesthesiologists physical status, extent of lymph node dissection, and Japanese Classification of Gastric Carcinoma stage. Short-term outcomes and prognoses were compared. RESULTS: We identified 37 propensity score-matched pairs. The median operative time was significantly shorter, and postoperative stay was longer in the EG. In terms of postoperative outcomes, the rates of all complications were comparable. The median follow-up period of the EG and non-EG was 11.5 (1-106.4) months and 35.7 (1-110.0) months, respectively; there were significant differences in 5-year overall survival between the two groups (EG, 58.5% vs. non-EG, 91.5%; P = 0.031). However, there were no significant differences in 5-year disease-specific survival (EG, 62.1% vs. non-EG, 91.5%; P = 0.068) or 5-year disease-free survival (EG, 52.9% vs. non-EG, 60.8%; P = 0.132). CONCLUSIONS: LTG seems to be safe and feasible in elderly patients. LTG had a limited effect on morbidity, disease recurrence, and survival in elderly patients. Therefore, age should not prevent elderly patients from benefitting from LTG.
  • Elif Bilgic, Allan Okrainec, Sofia Valanci, Adam Di Palma, Andras Fecso, Pepa Kaneva, Caterina Masino, Yusuke Watanabe, Melina C Vassiliou, Liane S Feldman, Gerald M Fried
    Surgical endoscopy 2022年1月8日  査読有り
    BACKGROUND: Telesimulation helps overcome limitations in time and local expertise by eliminating the need for the learner and educator to be physically co-located, especially important during COVID-19. We investigated whether teaching advanced laparoscopic suturing (ALS) through telesimulation is feasible, effective, and leads to improved suturing in the operating room (OR). METHODS: In this prospective feasibility study, three previously developed 3D-printed ALS tasks were used: needle handling (NH), suturing under tension (UT), and continuous suturing (CS). General surgery residents (PGY4-5) underwent 1-month of telesimulation training, during which an expert educator at one site remotely trained residents at the other site over 2-3 teaching sessions. Trainees were assessed in the three tasks and in the OR at three time points: baseline(A1), control period(A2), and post-intervention(A3) and completed questionnaires regarding educational value and usability of telesimulation. Paired t-test was used to compare scores between the three assessment points. RESULTS: Six residents were included. Scores for UT improved significantly post-intervention A3(568 ± 60) when compared to baseline A1(416 ± 133) (p < 0.019). Similarly, scores for CS improved significantly post-intervention A3(756 ± 113) vs. baseline A1(539 ± 211) (p < 0.02). For intraoperative assessments, scores improved significantly post-intervention A3(21 ± 3) when compared to both A1(17 ± 4) (p < 0.018) and A2(18 ± 4) (p < 0.0008). All residents agreed that tasks were relevant to practice, helped improve technical competence, and adequately measured suturing skill. All residents found telesimulation easy to use, had strong educational value, and want the system to be incorporated into their training. CONCLUSION: The use of telesimulation for remotely training residents using ALS tasks was feasible and effective. Residents found value in training using the tasks and telesimulation system, and improved ALS skills in the OR. As the pandemic has caused a major structural shift in resident education, telesimulation can be an effective alternative to on-site simulation programs. Future research should focus on how telesimulation can be effectively incorporated into training programs.
  • 七戸 俊明, 岡村 圭祐, 土川 貴裕, 中村 透, 村上 壮一, 海老原 裕磨, 倉島 庸, 野路 武寛, 浅野 賢道, 中西 喜嗣, 田中 公貴, 渡邊 祐介, 松井 あや, 平野 聡
    日本内視鏡外科学会雑誌 26(7) PD12-6 2021年12月  
  • Toru Yamada, Yoshitsugu Nakanishi, Hideyuki Hayashi, Shigeki Tanishima, Ryo Mori, Kyoko Fujii, Keisuke Okamura, Takahiro Tsuchikawa, Toru Nakamura, Takehiro Noji, Toshimichi Asano, Aya Matsui, Kimitaka Tanaka, Yusuke Watanabe, Yo Kurashima, Yuma Ebihara, Soichi Murakami, Toshiaki Shichinohe, Tomoko Mitsuhashi, Satoshi Hirano
    HPB : the official journal of the International Hepato Pancreato Biliary Association 24(7) 1035-1043 2021年11月25日  査読有り
    BACKGROUND: Lymph node metastasis (LNM) is one of the most adverse prognostic factors in extrahepatic cholangiocarcinoma (EHCC) cases. As next-generation sequencing technology has become more widely available, the genomic profile of biliary tract carcinoma has been clarified. However, whether LNMs have additional genomic alterations in patients with EHCC has not been investigated. Here, we aimed to compare the genomic alterations between primary tumors and matched LNMs in patients with EHCC. METHODS: Sixteen patients with node-positive EHCCs were included. Genomic DNA was extracted from tissue samples of primary tumors and matched LNMs. Targeted amplicon sequencing of 160 cancer-related genes was performed. RESULTS: Among the 32 tumor samples from 16 patients, 91 genomic mutations were identified. Genomic mutations were noted in 31 genes, including TP53, MAP3K1, SMAD4, APC, and ARID1A. TP53 mutations were most frequently observed (12/32; 37.5%). Genomic mutation profiles were highly concordant between primary tumors and matched LNMs (13/16; 81.3%), and an additional genomic mutation of CDK12 was observed in only one patient. CONCLUSION: Genomic mutations were highly concordant between primary tumors and matched LNMs, suggesting that genotyping of archived primary tumor samples may help predict genomic mutations of metastatic tumors in patients with EHCC.
  • Daichi Kitaguchi, Yusuke Watanabe, Amin Madani, Daniel A. Hashimoto, Ozanan R. Meireles, Nobuyoshi Takeshita, Kensaku Mori, Masaaki Ito
    Annals of Surgery Publish Ahead of Print(4) e609-e611 2021年11月23日  査読有り
  • Yoshitsugu Nakanishi, Satoshi Hirano, Keisuke Okamura, Takahiro Tsuchikawa, Toru Nakamura, Takehiro Noji, Toshimichi Asano, Aya Matsui, Kimitaka Tanaka, Soichi Murakami, Yuma Ebihara, Yo Kurashima, Yusuke Watanabe, Toshiaki Shichinohe
    Surgery today 52(5) 853-853 2021年11月18日  
  • 野路 武寛, 松井 あや, 田中 公貴, 中西 喜嗣, 渡邉 祐介, 浅野 賢道, 海老原 裕磨, 倉島 庸, 中村 透, 村上 壮一, 土川 貴裕, 岡村 圭佑, 七戸 俊明, 川本 泰之, 桑谷 将城, 平野 聡
    日本消化器外科学会雑誌 54(Suppl.2) 155-155 2021年11月  
  • 村上 壮一, 廣瀬 和幸, 東嶋 宏泰, 出口 琢人, 渡邊 祐介, 倉島 庸, 海老原 裕磨, 七戸 俊明, 早川 峰司, 平野 聡
    日本救急医学会雑誌 32(12) 1234-1234 2021年11月  
  • 七戸 俊明, 村上 壮一, 海老原 裕磨, 倉島 庸, 岡村 圭祐, 土川 貴裕, 中村 透, 野路 武寛, 浅野 賢道, 中西 喜嗣, 松井 あや, 田中 公貴, 渡邊 祐介, 池田 篤, 平野 聡
    Japanese Journal of Acute Care Surgery 11(1) 88-88 2021年11月  
  • 新堂 大我, 村上 壮一, 富田 明子, 早川 峰司, 松井 あや, 出口 琢人, 東嶋 宏泰, 池田 篤, 渡邊 祐介, 田中 公貴, 中西 喜嗣, 浅野 賢道, 野路 武寛, 倉島 庸, 海老原 裕磨, 中村 透, 土川 貴裕, 岡村 圭祐, 七戸 俊明, 平野 聡
    Japanese Journal of Acute Care Surgery 11(1) 124-124 2021年11月  
  • 武田 真太郎, 村上 壮一, 松井 あや, 出口 琢人, 東嶋 宏泰, 石堂 敬太, 宮谷内 健吾, 池田 篤, 渡邊 祐介, 田中 公貴, 中西 喜嗣, 浅野 賢道, 野路 武寛, 倉島 庸, 海老原 裕磨, 中村 透, 土川 貴裕, 岡村 圭祐, 七戸 俊明, 平野 聡
    Japanese Journal of Acute Care Surgery 11(1) 124-124 2021年11月  
  • 野路 武寛, 松井 あや, 田中 公貴, 中西 喜嗣, 渡邉 祐介, 浅野 賢道, 海老原 裕磨, 倉島 庸, 中村 透, 村上 壮一, 土川 貴裕, 岡村 圭佑, 七戸 俊明, 川本 泰之, 桑谷 将城, 平野 聡
    日本消化器外科学会雑誌 54(Suppl.2) 155-155 2021年11月  
  • Yoshitsugu Nakanishi, Satoshi Hirano, Keisuke Okamura, Takahiro Tsuchikawa, Toru Nakamura, Takehiro Noji, Toshimichi Asano, Aya Matsui, Kimitaka Tanaka, Soichi Murakami, Yuma Ebihara, Yo Kurashima, Yusuke Watanabe, Toshiaki Shichinohe
    Surgery today 52(5) 844-852 2021年11月1日  査読有り
    PURPOSE: This retrospective study aimed to clarify whether the postoperative prognosis differs between right and left hepatectomy for Bismuth type I/II perihilar cholangiocarcinoma. METHODS: Preoperative images of 195 patients with perihilar cholangiocarcinoma were reexamined. Patients with Bismuth type I/II perihilar cholangiocarcinoma without a difference in extraductal tumor invasion between the right and left sides of the hepatic portal region were classified into those undergoing left (L group) or right (R group) hepatectomy. RESULTS: Twenty-three patients (11.8%) were classified into the L group and 33 (16.9%) into the R group. All eight patients with pTis/1 belonged to the L group. The L group had significantly less liver failure than the R group (p = 0.001). One patient (4.3%) in the L group and four patients (12.1%) in the R group died from postoperative complications. Among 48 patients with pT2, the L group tended to have better overall survival (median, 12.2 vs. 5.6 years; p = 0.072), but not recurrence-free survival (median, 9.1 vs. 3.6 years; p = 0.477), in comparison to the R group. CONCLUSIONS: Postoperative survival after left hepatectomy for Bismuth type I/II perihilar cholangiocarcinoma is expected to be as long as that after right hepatectomy.
  • Emad Aljohani, Fahad Almadi, Yusuke Watanabe, Abdullah Aldawsari, Mohammed Alsuwaigh, Rakan Alanazi, Salman Alwadani, Talal Alfayez, Ziad Alanazi
    International Surgery 2021年7月19日  査読有り
    Objective: To assess General Surgery trainee’s knowledge about safe use of energy devices in two tertiary hospitals in Riyadh, Saudi Arabia Background: Electro surgery is the use of high-frequency electrical energy to achieve cutting, and coagulation. This method has become ubiquitous worldwide for the purpose of achieving rapid hemostasis and rapid dissection of tissues Methods:   Participants completed a 35-item multiple choice question examination, testing critical knowledge of ES. The examination was developed according to the objectives and blueprints of SAGES’ Fundamental Use of Surgical Energy curriculum. Sections of the examination included: principles of ES, ES-related adverse events, monopolar and bipolar devices, and pediatric considerations and interference with implantable devices.’’ Scores were compared between juniors and seniors participants. Results: A total of 51 general surgical trainees from two academic hospitals completed the assessment. 15.69% of the participants correctly answered 30 questions out of 35 questions, 39.22% of the participants responded correctly to 20 questions out of 35 answers, and 45.09 who responded correctly to less than 20 questions. It was found that 52.2% of the individuals with a low level of understanding were junior residents as opposed to 87.5% of the participants with the highest level of understanding were senior residents with a significant P-value of 0.04. Conclusions: majority of general surgery residents enrolled in the Saudi Arabian board of surgery lack adequate knowledge about the safe and efficient use of surgical energy devices. The level of understanding is lower among the junior residents than seniors.
  • Fateme Rajabiyazdi, Roshni Alam, Aditya Pal, Joel Montanez, Susan Law, Nicolò Pecorelli, Yusuke Watanabe, Luciana D. Chiavegato, Massimo Falconi, Satoshi Hirano, Nancy E. Mayo, Lawrence Lee, Liane S. Feldman, Julio F. Fiore
    JAMA Surgery 156(8) 758-765 2021年5月12日  査読有り
    Importance: Postoperative recovery is difficult to define or measure. Research addressing interventions aimed to improve recovery after abdominal surgery often focuses on measures such as duration of hospital stay and complication rates. Although these clinical parameters are relevant, understanding patients' perspectives regarding postoperative recovery is fundamental to guiding patient-centered care. Objective: To elucidate the meaning of recovery from the perspective of patients undergoing abdominal surgery. Design, Setting, and Participants: This international qualitative study involved semistructured interviews with patients recovering from abdominal surgery from October 2016 to November 2018 in tertiary hospitals in 4 countries (Canada, Italy, Brazil, and Japan). A purposive maximal variation sampling method was used to ensure the recruitment of patients with varying demographic, clinical, and surgical characteristics. Data on race were not collected. Each interview lasted between 1 and 2 hours. Interviews were recorded and then transcribed verbatim. Transcripts were then analyzed using an inductive thematic analysis approach. Data analysis was conducted from July 2019 to September 2019. Main Outcomes and Measures: The qualitative analysis revealed themes reflecting the meaning of recovery from the perspective of patients undergoing abdominal surgery. Results: Thirty patients recovering from abdominal surgery were interviewed (15 [50%] female; mean [SD] age, 57 [18] years; 10 [33%] underwent major surgery; 16 [53%] underwent laparoscopic surgery). The interviews revealed that for patients undergoing abdominal surgery, the meaning of recovery embodied 5 overarching themes: (1) returning to habits and routines, (2) resolution of symptoms, (3) overcoming mental strains, (4) regaining independence, and (5) enjoying life. Themes associating the meaning of recovery to traditional parameters, such as earlier hospital discharge or absence of complications, were not identified in the interviews. Conclusions and Relevance: This qualitative study suggests that the meaning of recovery from the perspective of patients undergoing abdominal surgery goes beyond traditional clinical parameters. The elements of recovery identified in this study should be taken into account in patient-surgeon discussions about recovery and when developing patient-centered strategies to improve postoperative outcomes.
  • Akihiro Kondo, Yusuke Watanabe, Minoru Ishida, Yasuyuki Suzuki, Satoshi Hirano
    Annals of Surgery 273(5) e168-e170 2021年5月  査読有り筆頭著者責任著者
  • 村上 壮一, 廣瀬 和幸, 東嶋 宏泰, 楢崎 肇, 松井 あや, 渡邊 祐介, 田中 公貴, 中西 喜嗣, 浅野 賢道, 野路 武寛, 海老原 裕磨, 倉島 庸, 中村 透, 土川 貴裕, 岡村 圭祐, 七戸 俊明, 平野 聡
    日本外科学会定期学術集会抄録集 121回 PD-2 2021年4月  
  • 中村 透, 浅野 賢道, 岡村 圭祐, 土川 貴裕, 村上 壮一, 倉島 庸, 海老原 裕磨, 野路 武寛, 中西 喜嗣, 田中 公貴, 渡邊 祐介, 松井 あや, 七戸 俊明, 平野 聡
    日本外科学会定期学術集会抄録集 121回 PD-5 2021年4月  
  • 倉島 庸, サシーム・パウデル, 渡邊 祐介, 海老原 裕磨, 村上 壮一, 七戸 俊明, 平野 聡
    日本内視鏡外科学会雑誌 25(7) BSP2-1 2021年3月  
  • 桐山 琴衣, 倉島 庸, サシーム・パウデル, 渡邊 祐介, 海老原 裕磨, 村上 壮一, 七戸 俊明, 平野 聡
    日本内視鏡外科学会雑誌 25(7) BSP2-4 2021年3月  
  • 桐山 琴衣, 倉島 庸, サシーム・パウデル, 渡邊 祐介, 海老原 裕磨, 村上 壮一, 七戸 俊明, 平野 聡
    日本内視鏡外科学会雑誌 25(7) BSP4-3 2021年3月  
  • Yusuke Watanabe, Pascal Fuchshuber, Takafumi Homma, Elif Bilgic, Amin Madani, Naoki Hiki, Ivor Cammack, Takehiro Noji, Yo Kurashima, Toshiaki Shichinohe, Satoshi Hirano
    Surgical Innovation 155335062090461-155335062090461 2020年3月18日  査読有り筆頭著者責任著者
    Objective. We analyzed the underlying principles of an unmodulated very-low-voltage (VLV) mode, designated as “soft coagulation” in hemostasis, and demonstrate its clinical applications. Summary Background Data. While the advantage of the VLV mode has been reported across surgical specialties, the basic principle has not been well described and remains ambiguous. Methods. Characteristics of major electrosurgical modes were measured in different settings. For the VLV mode, the tissue effect and electrical parameters were assessed in simulated environments. Results. The VLV mode achieved tissue coagulation with the lowest voltage compared with the other modes in any settings. With increasing impedance, the voltage of the VLV mode stayed very low at under 200 V compared with other modes. The VLV mode constantly produced effective tissue coagulation without carbonization. We have demonstrated the clinical applications of the method. Conclusions. The voltage of the VLV mode consistently stays under 200 V, resulting in tissue coagulation with minimal vaporization or carbonization. Therefore, the VLV mode produces more predictable tissue coagulation and minimizes undesirable collateral thermal tissue effects, enabling nerve- and function-preserving surgery. The use of VLV mode through better understanding of minimally invasive way of using electrosurgery may lead to better surgical outcomes.
  • The International Journal of Microdentistry 2020年  招待有り筆頭著者責任著者
  • Yokoyama S, Mizunuma K, Kurashima Y, Watanabe Y, Mizota T, Poudel S, Kikuchi T, Kawai F, Shichinohe T, Hirano S
    Pediatric surgery international 35(10) 1085-1094 2019年8月  査読有り
  • Alam R, Montanez J, Law S, Lee L, Pecorelli N, Watanabe Y, Chiavegato LD, Falconi M, Hirano S, Mayo NE, Feldman LS, Fiore JF J
    Surgical Endoscopy 34(6) 2665-2674 2019年8月  査読有り
  • Poudel S, Watanabe Y, Ito YM, Shichinohe T, Kawase H, Tanaka K, Murakami Y, Hirano S
    Journal of Surgical Education 76(4) 1101-1106 2019年7月  査読有り
  • Shinichiro Yokoyama, Yusuke Watanabe, Yo Kurashima, Akihiko Oshita, Yuji Nishizawa, Takeshi Naitoh, Fumitaka Nakamura, Satoru Kikuchi, Kazuhiro Noma, Saseem Poudel, Akihiro Suzuki, Yuichi Nishihara, Masaaki Ito, Satoshi Hirano
    Surgical endoscopy 33(7) 2242-2248 2019年7月  査読有り責任著者
    BACKGROUND: Recently, laparoscopic surgery (LS) has become a more common procedure than traditional open surgery. Although LS-related adverse events have been reported, there is no formal, standardized curriculum to teach the fundamentals of LS in Japan. Understanding surgeons' knowledge regarding LS is crucial for developing an educational curriculum. The purpose of this study was to determine the baseline knowledge on LS of surgeons and surgical trainees in Japan. METHODS: Participants completed 24 multiple-choice questions testing basic cognitive knowledge of LS and a questionnaire regarding the status of laparoscopic education. The examination was developed according to the 13 content domains of the Fundamentals of Laparoscopic Surgery (FLS) program. Scores were compared between post-graduate year (PGY) > 5 and PGY 1-5 participants. Data are expressed as median scores and interquartile ranges. Wilcoxon signed-rank test was used for statistical analysis. RESULTS: A total of 195 surgeons and surgical trainees from 10 teaching hospitals (PGY1-5: 66, PGY > 5: 129) across Japan completed the examination. The median score in the entire cohort was 75 [67; 83] %, with significantly higher scores in the PGY > 5 group compared to the PGY1-5 group (79 [75; 83] % vs. 67 [58; 75] %, p < 0.001). The differences in performance were due to better scores for PGY > 5 group on the sections "equipment," "patient considerations," "abdominal access," "tissue handling," "hemorrhage and hemostasis," "tissue approximation," and "exiting the abdomen." Overall, the median scores in the "energy sources" and "establishment and physiology of the pneumoperitoneum" subsections were lower than in other domains. All participants agreed on the need for fundamental knowledge and a formal educational curriculum. CONCLUSIONS: Compared to experienced surgeons, surgical trainees had lesser knowledge about performing LS. Regardless of the years of experience, there are crucial knowledge gaps in specific areas regarding safe LS that should be addressed by implementing an educational curriculum.
  • Kurashima Y, Watanabe Y, Hiki N, Poudel S, Kitagami H, Ebihara Y, Murakami S, Shichinohe T, Hirano S
    Surgical endoscopy 33(12) 3945-3952 2019年2月  査読有り
  • Mathis R, Watanabe Y, Ghaderi I, Nepomnayshy D
    Surgical Endoscopy 2019年  査読有り
  • Tomoko Mizota, Yo Kurashima, Saseem Poudel, Yusuke Watanabe, Toshiaki Shichinohe, Satoshi Hirano
    American Journal of Surgery 216(1) 88-92 2018年7月1日  査読有り
  • Elif Bilgic, Satoshi Endo, Ekaterina Lebedeva, Madoka Takao, Katherine M. McKendy, Yusuke Watanabe, Liane S. Feldman, Melina C. Vassiliou
    Surgical Endoscopy and Other Interventional Techniques 32(7) 3009-3023 2018年7月1日  査読有り
  • Sekiya S, Imamura K, Takeuchi S, Teramura K, Watanabe Y, Tamoto E, Takada M, Kinoshita Y, Anbo Y, Nakamura F, Kashimura N, Noguchi H, Miura K, Hirano S
    Surgical case reports 4(1) 58-58 2018年6月  査読有り
  • Elif Bilgic, Madoka Takao, Pepa Kaneva, Satoshi Endo, Toshitatsu Takao, Yusuke Watanabe, Katherine M. McKendy, Liane S. Feldman, Melina C. Vassiliou
    Surgical Innovation 25(3) 286-290 2018年6月1日  査読有り

MISC

 199

書籍等出版物

 2

共同研究・競争的資金等の研究課題

 12

産業財産権

 2