研究者検索結果一覧 梅澤 喜夫 梅澤 喜夫ウメザワ ヨシオ (Yoshio Umezawa) ダウンロードする帳票の形式を下記より選択して下さい 「教育研究等環境」形式 「文科省帳票様式第4号 ①履歴書」形式 「文科省帳票様式第4号 ②教育研究業績書」形式 「教員名簿」形式 基本情報 所属武蔵野大学 薬学研究所 客員教授学位理学博士J-GLOBAL ID200901096118618594researchmap会員ID1000013807 研究キーワード 2 分析化学 Analytical Chemistry 研究分野 1 ナノテク・材料 / 分析化学 / 学歴 4 - 1972年 東京大学 理学系研究科 化学 - 1972年 東京大学 - 1967年 東京大学 理学部 化学科 - 1967年 東京大学 受賞 3 2000年 日本分析化学会学会賞 1979年 日本分析化学会奨励賞 1973年 電気化学協会進歩賞 MISC 212 How Can Ca2+ Selectively Activate Recoverin in the Presence of Mg2+? Surface Plasmon Resonance and FT-IR Spectroscopic Studies.(共著) ┣DBBiochemistry(/)-┫DB 39(47) 14495-14503 2000年 Electrochemical detection of a one-base mismatch in an oligonucleotide using ion-channel sensors with self-assembled PNA monolayers.(共著) ┣DBElectroanalysis(/)-┫DB 12(16) 1272-1276 2000年 A Screening Method for Substrates of Multidrug Resistance-associated Protein(MRP).(共著) ┣DBAnal. Chim. Acta(/)-┫DB 423(2) 197-203 2000年 Methods of Analysis. Anal. Chem. (Editorial) 72(13) 437A 2000年 A Screening Method for Antigen-Specific IgE Using Mast Cells Based on Intracellular Calcium Signaling. Anal. Chem. 72(11) 2653-2658 2000年 Lifetime of Ion-Selective Electrodes Based on Charged Ionophores. Anal. Chem. 72(8) 1843-1852 2000年 Quartz Crystal Microbalance for L-Leucine Sensing Based on Growth of L-Leucine Crystals Immobilized on a Monolayer of 11-Mercaptoundecanoic Aicd. Anal. Chim. Acta 413(1/2) 223-227 2000年 Cationic or Anionic Sites? Selectivity Optimization of Ion-Selective Electrodes Based on Charged Ionophores. Anal. Chem. 72(7) 1618-1631 2000年 Development of an Ion-Channel Sensor for Heparin Detection. Anal. Chim. Acta 411(1/2) 163-173 2000年 An SPR-based Screening Method for Agonist Selectivity for Insulin Signaling Pathways Based on the Binding of Phosphotyrosine to its Specific Binding Protein. Anal. Chem. 72(1) 6-11 2000年 Metal ion selectivity for formation of the calmodulin-metal-target peptide ternary complex studied by surface plasmon resonance spectroscopy T Ozawa, K Sasaki, Y Umezawa BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 1434(2) 211-220 1999年10月 Self-assembly of a tricarboxylate receptor through thioamide groups and its use for electrochemical detection of protonated amines H Aoki, P Buhlmann, Y Umezawa JOURNAL OF ELECTROANALYTICAL CHEMISTRY 473(1-2) 105-112 1999年9月 Dopamine-selective response in membrane potential by homooxacalix[3]arene triether host incorporated in PVC liquid membrane K Odashima, K Yagi, K Tohda, Y Umezawa BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 9(16) 2375-2378 1999年8月 Apparently "non-Nernstian" equilibrium responses based on complexation between the primary ion and a secondary ion in the liquid ISE membrane P Buhlmann, Y Umezawa ELECTROANALYSIS 11(10-11) 687-693 1999年7月 An Ion-Selective Electrode for Acetate Based on a Urea-Functionalized Porphyrin as a Hydrogen-Bonding Ionophore. Anal. Chem. 71(5) 1049-1054 1999年 Ion-channel - Mimetic sensors based on self-assembled monolayers of phosphate esters: High selectivity for trivalent cations M Takaya, P Buhlmann, Y Umezawa MIKROCHIMICA ACTA 132(1) 55-60 1999年 Voltammetric Detection of the Polycation Protamine by the Use of Electrodes Modified with Self-Assembled Monolayers of Thioctic Acid. Anal. Chem. 71(22) 5109-5115 1999年 A Fluorescent Indicator for Tyrosine Phosphorylation-Based Insulin Signaling Pathways. Anal. Chem. 71(18) 3948-3954 1999年 Effect of Dissolved Oxygen on the Response of Cu((]G0002[)) Ion-Selective Electrodes in Metal Buffer Solutions. Anal. Chim. Acta 395(1/2) 53-63 1999年 Quartz crystal microbalance for selenite sensing based on growth of cadmium selenite crystals immobilized on a monolayer of phosphorylated 11-mercapto-1-undecanol H Eun, Y Umezawa MIKROCHIMICA ACTA 131(3-4) 177-185 1999年 Polypyrrole-Modified Tips for Functional Group Recognition in Scanning Tunneling Microscopy. Anal. Chem. 71(9) 1699-1705 1999年 Observation of Silver and Hydrogen Ion Binding to Self-Assembled Monolayers with Chemically Modified AFM Tips. Langmuir 15(8) 2788-2793 1999年 Ion-Channel-Mimetic Sensing of Hydrophilic Anions Based on Monolayers of a Hydrogen Bond Forming Receptor. Anal. Chem. 71(6) 1183-1187 1999年 A Method for Evaluating Chemical Selectivity of Agonists for Glutamate Receptor Channels Incorporated in Liposomes Based on an Agonist-Induced Ion Flux Measured by Ion-Selective Electrodes. J. Pharm. Biomed. Anal. 19(1/2) 205-216 1999年 Lasalocid A facilitated dopamine uphill transport and concentration into liposomes driven by pH gradient generated by bacteriorhodopsin under illumination Z Quan, M Sugawara, Y Umezawa BIOSENSORS & BIOELECTRONICS 13(11) 1157-1164 1998年11月 Ionophore incorporated bilayer lipid membranes that selectively respond to metal ions and induce membrane permeability changes H Sato, H Hakamada, Y Yamazaki, M Uto, M Sugawara, Y Umezawa BIOSENSORS & BIOELECTRONICS 13(9) 1035-1046 1998年10月 A systematic study on the complexation of quaternary ammonium salts and neutral phenols K Odashima, T Ito, K Tohda, Y Umezawa CHEMICAL & PHARMACEUTICAL BULLETIN 46(8) 1248-1253 1998年8月 Synthesis and photoswitchable complexation/extraction properties of lipophilic azobis(benzo-15-crown-5) ionophores for alkali metal cations K Odashima, K Tohda, S Yoshiyagawa, S Yamashita, M Kataoka, Y Umezawa HETEROCYCLES 47(2) 847-856 1998年2月 Co-Ion Interference for Ion-Selective Electrodes Based on Charged and Neutral Ionophores : A Comparison. Anal. Chem. 70(20) 4291-4303 1998年 An Ion-Selective Electrode for Acetate Based on an Urea-Functionalized Porphyrin as a Hydrogen-Bonding Ionophore. Anal. Chem. 71(5) 1049-1054 1998年 Sulfate Ion Sensing Based on a Quartz-Crystal Microbalance Immobilized with Barium Sulfate Crystals Grown on a Self-Assembled Monolayer of Phosphorylated 11-Mercapto-1-Undecanol. Anal. Chim. Acta 375(1/2) 155-165 1998年 A Cation-Selective Electrode Based on Cu((]G0001[)) and Ni((]G0002[)) Hexacyanoferrates : Dual Response Mechanisms, Selective Uptake or Adsorption of Analyte Cations. Electrochim. Acta 43(23) 3431-3441 1998年 An Assay Method for Evaluating Chemical Selectivity of Agonists for Insulin Signaling Pathways Based on Agonist-Induced Phosphorylation of a Target Peptide. Anal. Chem. 70(11) 2345-2352 1998年 On the Mechanism of Unexpected Potentiometric Response to Neutral Phenols by Liquid Membranes Based on Quaternary Ammonium Salts-Systematic Experimental and Theoretical Approaches. J. Am. Chem. Soc. 120(13) 3049-3059 1998年 Alkali metal ion-selective electrodes based on relevant alkali metal ion doped manganese oxides Y Tani, Y Umezawa MIKROCHIMICA ACTA 129(1-2) 81-90 1998年 A Variety of Lipophilic Amines Incorporated in Liquid Membranes Exhibit Potentiometric Responses to Neutral Phenols. Takashi ITO, Hanna RADECKA, Kayoko UMEZAWA, Tatsuji KIMURA, Akiko YASHIRO, Xiao Ming LIN, Masamitsu KATAOKA, Eiichi KIMURA, Jonathan L. SESSLER, Kazunori ODASHIMA, Yoshio UMEZAWA Anal. Sci. 14(1) 89-98 1998年 A Phase Boundary Potential Model for Apparently"Twice-Nernstian"Response of Liquid Membrane Ion-Selective Electrodes. Anal. Chem. 70(3) 445-454 1998年 Potentiometric Responses of Expanded Porphyrin-Incorporated Liquid-Membrane Electrodes toward a Series of Inorganic and Organic Anions. Xiao Ming LIN, Kayoko UMEZAWA, Koji TOHDA, Hiroyuki FURUTA, Jonathan L. SESSLER, Yoshio UMEZAWA Anal. Sci. 14(1) 99-108 1998年 Scanning Tunneling Microscopy Using Chemically Modified Tips. Anal. Chem. 70(2) 255-259 1998年 Application of a Bis-Thiourea Ionophore for an Anion Selective Electrode with a Remarkable Sulfate Selectivity. Anal. Chim. Acta 358(1) 35-44 1998年 Ion-selective charge separation at the phase boundary of ionophore-incorporated liquid membranes as studied by optical second-harmonic generation K Tohda, S Yoshiyagawa, Y Umezawa JOURNAL OF MOLECULAR STRUCTURE 408 155-160 1997年6月 Fluorescence-mediated sensing of guanosine derivatives based on multitopic hydrogen bonding S Amemiya, P Buhlmann, Y Umezawa CHEMICAL COMMUNICATIONS (11) 1027-1028 1997年6月 Strong hydrogen bond-mediated complexation of H2PO4- by neutral bis-thiourea hosts P Buhlmann, S Nishizawa, KP Xiao, Y Umezawa TETRAHEDRON 53(5) 1647-1654 1997年2月 Channel mimetic sensing membranes for nucleotides based on multitopic hydrogen bonding K Tohda, S Amemiya, T Ohki, S Nagahora, S Tanaka, P Buhlmann, Y Umezawa ISRAEL JOURNAL OF CHEMISTRY 37(2-3) 267-275 1997年 Modification of Silicon Nitride Tips with Trichlorosilane SAMs for Chemical Force Microscopy. Langmuir 13(16) 4323-4332 1997年 Photoswichable Azobis(benzo-15-crown-5) Derivatives as a Molecular Probe for Phase Boundary Potentials at Ion-Selective Poly(vinyl chloride)Liquid Membranes. Anal. Chem. 69(16) 3360-3369 1997年 An Optical Method for Evaluating Ion Selectivity for Calcium Signaling Pathways in the Cell. Anal. Chem. 69(15) 3081-3085 1997年 Hydrogen Bond Based Recognition of Nucleotides by Neutral-Carrier Ion-Selective Electrodes. Anal. Chim. Acta 341(2/3) 129-139 1997年 Electrochemical evaluation of chemical selectivity of glutamate receptor ion channel proteins with a multi-channel sensor M Sugawara, A Hirano, M Rehak, J Nakanishi, K Kawai, H Sato, Y Umezawa BIOSENSORS & BIOELECTRONICS 12(5) 425-439 1997年 Potentiometric Responses of Ionophore-Incorporated Bilayer Lipid Membranes with and without Added Anionic Sites Anal. Sci. 13(3) 437-446 1997年 «12345» 所属学協会 10 日本内分泌撹乱化学物質学会(環境ホルモン学会) 日本生化学会 生物物理学会 電気分析化学会 アメリカ電気化学会 もっとみる 共同研究・競争的資金等の研究課題 4 分子探針と化学選択性STMの開発 生体系の非破壊分析法の開発;細胞情報の増強・抑制物質の分析法の開発,とくに生細胞内情報伝達の可視化プローブ開発 Non-destructive analysis of Inter-and Intracellular molecular mechanisms : methodology development Chemically Sensitive Interfaces and its Application to Chemical Sensing
梅澤 喜夫ウメザワ ヨシオ (Yoshio Umezawa) ダウンロードする帳票の形式を下記より選択して下さい 「教育研究等環境」形式 「文科省帳票様式第4号 ①履歴書」形式 「文科省帳票様式第4号 ②教育研究業績書」形式 「教員名簿」形式 基本情報 所属武蔵野大学 薬学研究所 客員教授学位理学博士J-GLOBAL ID200901096118618594researchmap会員ID1000013807 研究キーワード 2 分析化学 Analytical Chemistry 研究分野 1 ナノテク・材料 / 分析化学 / 学歴 4 - 1972年 東京大学 理学系研究科 化学 - 1972年 東京大学 - 1967年 東京大学 理学部 化学科 - 1967年 東京大学 受賞 3 2000年 日本分析化学会学会賞 1979年 日本分析化学会奨励賞 1973年 電気化学協会進歩賞 MISC 212 How Can Ca2+ Selectively Activate Recoverin in the Presence of Mg2+? Surface Plasmon Resonance and FT-IR Spectroscopic Studies.(共著) ┣DBBiochemistry(/)-┫DB 39(47) 14495-14503 2000年 Electrochemical detection of a one-base mismatch in an oligonucleotide using ion-channel sensors with self-assembled PNA monolayers.(共著) ┣DBElectroanalysis(/)-┫DB 12(16) 1272-1276 2000年 A Screening Method for Substrates of Multidrug Resistance-associated Protein(MRP).(共著) ┣DBAnal. Chim. Acta(/)-┫DB 423(2) 197-203 2000年 Methods of Analysis. Anal. Chem. (Editorial) 72(13) 437A 2000年 A Screening Method for Antigen-Specific IgE Using Mast Cells Based on Intracellular Calcium Signaling. Anal. Chem. 72(11) 2653-2658 2000年 Lifetime of Ion-Selective Electrodes Based on Charged Ionophores. Anal. Chem. 72(8) 1843-1852 2000年 Quartz Crystal Microbalance for L-Leucine Sensing Based on Growth of L-Leucine Crystals Immobilized on a Monolayer of 11-Mercaptoundecanoic Aicd. Anal. Chim. Acta 413(1/2) 223-227 2000年 Cationic or Anionic Sites? Selectivity Optimization of Ion-Selective Electrodes Based on Charged Ionophores. Anal. Chem. 72(7) 1618-1631 2000年 Development of an Ion-Channel Sensor for Heparin Detection. Anal. Chim. Acta 411(1/2) 163-173 2000年 An SPR-based Screening Method for Agonist Selectivity for Insulin Signaling Pathways Based on the Binding of Phosphotyrosine to its Specific Binding Protein. Anal. Chem. 72(1) 6-11 2000年 Metal ion selectivity for formation of the calmodulin-metal-target peptide ternary complex studied by surface plasmon resonance spectroscopy T Ozawa, K Sasaki, Y Umezawa BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 1434(2) 211-220 1999年10月 Self-assembly of a tricarboxylate receptor through thioamide groups and its use for electrochemical detection of protonated amines H Aoki, P Buhlmann, Y Umezawa JOURNAL OF ELECTROANALYTICAL CHEMISTRY 473(1-2) 105-112 1999年9月 Dopamine-selective response in membrane potential by homooxacalix[3]arene triether host incorporated in PVC liquid membrane K Odashima, K Yagi, K Tohda, Y Umezawa BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 9(16) 2375-2378 1999年8月 Apparently "non-Nernstian" equilibrium responses based on complexation between the primary ion and a secondary ion in the liquid ISE membrane P Buhlmann, Y Umezawa ELECTROANALYSIS 11(10-11) 687-693 1999年7月 An Ion-Selective Electrode for Acetate Based on a Urea-Functionalized Porphyrin as a Hydrogen-Bonding Ionophore. Anal. Chem. 71(5) 1049-1054 1999年 Ion-channel - Mimetic sensors based on self-assembled monolayers of phosphate esters: High selectivity for trivalent cations M Takaya, P Buhlmann, Y Umezawa MIKROCHIMICA ACTA 132(1) 55-60 1999年 Voltammetric Detection of the Polycation Protamine by the Use of Electrodes Modified with Self-Assembled Monolayers of Thioctic Acid. Anal. Chem. 71(22) 5109-5115 1999年 A Fluorescent Indicator for Tyrosine Phosphorylation-Based Insulin Signaling Pathways. Anal. Chem. 71(18) 3948-3954 1999年 Effect of Dissolved Oxygen on the Response of Cu((]G0002[)) Ion-Selective Electrodes in Metal Buffer Solutions. Anal. Chim. Acta 395(1/2) 53-63 1999年 Quartz crystal microbalance for selenite sensing based on growth of cadmium selenite crystals immobilized on a monolayer of phosphorylated 11-mercapto-1-undecanol H Eun, Y Umezawa MIKROCHIMICA ACTA 131(3-4) 177-185 1999年 Polypyrrole-Modified Tips for Functional Group Recognition in Scanning Tunneling Microscopy. Anal. Chem. 71(9) 1699-1705 1999年 Observation of Silver and Hydrogen Ion Binding to Self-Assembled Monolayers with Chemically Modified AFM Tips. Langmuir 15(8) 2788-2793 1999年 Ion-Channel-Mimetic Sensing of Hydrophilic Anions Based on Monolayers of a Hydrogen Bond Forming Receptor. Anal. Chem. 71(6) 1183-1187 1999年 A Method for Evaluating Chemical Selectivity of Agonists for Glutamate Receptor Channels Incorporated in Liposomes Based on an Agonist-Induced Ion Flux Measured by Ion-Selective Electrodes. J. Pharm. Biomed. Anal. 19(1/2) 205-216 1999年 Lasalocid A facilitated dopamine uphill transport and concentration into liposomes driven by pH gradient generated by bacteriorhodopsin under illumination Z Quan, M Sugawara, Y Umezawa BIOSENSORS & BIOELECTRONICS 13(11) 1157-1164 1998年11月 Ionophore incorporated bilayer lipid membranes that selectively respond to metal ions and induce membrane permeability changes H Sato, H Hakamada, Y Yamazaki, M Uto, M Sugawara, Y Umezawa BIOSENSORS & BIOELECTRONICS 13(9) 1035-1046 1998年10月 A systematic study on the complexation of quaternary ammonium salts and neutral phenols K Odashima, T Ito, K Tohda, Y Umezawa CHEMICAL & PHARMACEUTICAL BULLETIN 46(8) 1248-1253 1998年8月 Synthesis and photoswitchable complexation/extraction properties of lipophilic azobis(benzo-15-crown-5) ionophores for alkali metal cations K Odashima, K Tohda, S Yoshiyagawa, S Yamashita, M Kataoka, Y Umezawa HETEROCYCLES 47(2) 847-856 1998年2月 Co-Ion Interference for Ion-Selective Electrodes Based on Charged and Neutral Ionophores : A Comparison. Anal. Chem. 70(20) 4291-4303 1998年 An Ion-Selective Electrode for Acetate Based on an Urea-Functionalized Porphyrin as a Hydrogen-Bonding Ionophore. Anal. Chem. 71(5) 1049-1054 1998年 Sulfate Ion Sensing Based on a Quartz-Crystal Microbalance Immobilized with Barium Sulfate Crystals Grown on a Self-Assembled Monolayer of Phosphorylated 11-Mercapto-1-Undecanol. Anal. Chim. Acta 375(1/2) 155-165 1998年 A Cation-Selective Electrode Based on Cu((]G0001[)) and Ni((]G0002[)) Hexacyanoferrates : Dual Response Mechanisms, Selective Uptake or Adsorption of Analyte Cations. Electrochim. Acta 43(23) 3431-3441 1998年 An Assay Method for Evaluating Chemical Selectivity of Agonists for Insulin Signaling Pathways Based on Agonist-Induced Phosphorylation of a Target Peptide. Anal. Chem. 70(11) 2345-2352 1998年 On the Mechanism of Unexpected Potentiometric Response to Neutral Phenols by Liquid Membranes Based on Quaternary Ammonium Salts-Systematic Experimental and Theoretical Approaches. J. Am. Chem. Soc. 120(13) 3049-3059 1998年 Alkali metal ion-selective electrodes based on relevant alkali metal ion doped manganese oxides Y Tani, Y Umezawa MIKROCHIMICA ACTA 129(1-2) 81-90 1998年 A Variety of Lipophilic Amines Incorporated in Liquid Membranes Exhibit Potentiometric Responses to Neutral Phenols. Takashi ITO, Hanna RADECKA, Kayoko UMEZAWA, Tatsuji KIMURA, Akiko YASHIRO, Xiao Ming LIN, Masamitsu KATAOKA, Eiichi KIMURA, Jonathan L. SESSLER, Kazunori ODASHIMA, Yoshio UMEZAWA Anal. Sci. 14(1) 89-98 1998年 A Phase Boundary Potential Model for Apparently"Twice-Nernstian"Response of Liquid Membrane Ion-Selective Electrodes. Anal. Chem. 70(3) 445-454 1998年 Potentiometric Responses of Expanded Porphyrin-Incorporated Liquid-Membrane Electrodes toward a Series of Inorganic and Organic Anions. Xiao Ming LIN, Kayoko UMEZAWA, Koji TOHDA, Hiroyuki FURUTA, Jonathan L. SESSLER, Yoshio UMEZAWA Anal. Sci. 14(1) 99-108 1998年 Scanning Tunneling Microscopy Using Chemically Modified Tips. Anal. Chem. 70(2) 255-259 1998年 Application of a Bis-Thiourea Ionophore for an Anion Selective Electrode with a Remarkable Sulfate Selectivity. Anal. Chim. Acta 358(1) 35-44 1998年 Ion-selective charge separation at the phase boundary of ionophore-incorporated liquid membranes as studied by optical second-harmonic generation K Tohda, S Yoshiyagawa, Y Umezawa JOURNAL OF MOLECULAR STRUCTURE 408 155-160 1997年6月 Fluorescence-mediated sensing of guanosine derivatives based on multitopic hydrogen bonding S Amemiya, P Buhlmann, Y Umezawa CHEMICAL COMMUNICATIONS (11) 1027-1028 1997年6月 Strong hydrogen bond-mediated complexation of H2PO4- by neutral bis-thiourea hosts P Buhlmann, S Nishizawa, KP Xiao, Y Umezawa TETRAHEDRON 53(5) 1647-1654 1997年2月 Channel mimetic sensing membranes for nucleotides based on multitopic hydrogen bonding K Tohda, S Amemiya, T Ohki, S Nagahora, S Tanaka, P Buhlmann, Y Umezawa ISRAEL JOURNAL OF CHEMISTRY 37(2-3) 267-275 1997年 Modification of Silicon Nitride Tips with Trichlorosilane SAMs for Chemical Force Microscopy. Langmuir 13(16) 4323-4332 1997年 Photoswichable Azobis(benzo-15-crown-5) Derivatives as a Molecular Probe for Phase Boundary Potentials at Ion-Selective Poly(vinyl chloride)Liquid Membranes. Anal. Chem. 69(16) 3360-3369 1997年 An Optical Method for Evaluating Ion Selectivity for Calcium Signaling Pathways in the Cell. Anal. Chem. 69(15) 3081-3085 1997年 Hydrogen Bond Based Recognition of Nucleotides by Neutral-Carrier Ion-Selective Electrodes. Anal. Chim. Acta 341(2/3) 129-139 1997年 Electrochemical evaluation of chemical selectivity of glutamate receptor ion channel proteins with a multi-channel sensor M Sugawara, A Hirano, M Rehak, J Nakanishi, K Kawai, H Sato, Y Umezawa BIOSENSORS & BIOELECTRONICS 12(5) 425-439 1997年 Potentiometric Responses of Ionophore-Incorporated Bilayer Lipid Membranes with and without Added Anionic Sites Anal. Sci. 13(3) 437-446 1997年 «12345» 所属学協会 10 日本内分泌撹乱化学物質学会(環境ホルモン学会) 日本生化学会 生物物理学会 電気分析化学会 アメリカ電気化学会 もっとみる 共同研究・競争的資金等の研究課題 4 分子探針と化学選択性STMの開発 生体系の非破壊分析法の開発;細胞情報の増強・抑制物質の分析法の開発,とくに生細胞内情報伝達の可視化プローブ開発 Non-destructive analysis of Inter-and Intracellular molecular mechanisms : methodology development Chemically Sensitive Interfaces and its Application to Chemical Sensing