The identification of novel molecular targets for antifungal drugs is critical due to limited treatment options and drug-resistance threats. We screened inhibitors of small GTPases, molecular switches in signal transduction, in Trichophyton rubrum...
Dermatophytes invade and colonize host superficial tissues via hyphal growth. Although cytoskeletal reorganization and its regulation are essential for hyphal growth, the molecular mechanisms in dermatophytes and their applicability as antifungal ...
Vicente Herranz-Pérez Jin Nakatani Masaki Ishii Toshiaki Katada Jose Manuel García-Verdugo Shinya Ohata
Scientific reports 12(1) 1493-1493 2022年1月 [査読有り]
The fusion protein of uncharacterised zinc finger translocation associated (ZFTA) and effector transcription factor of tumorigenic NF-κB signalling, RELA (ZFTA-RELA), is expressed in more than two-thirds of supratentorial ependymoma (ST-EPN-RELA),...
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