JOURNAL OF NATURAL MEDICINES 64(3) 266-274 2010年7月
In Ayurvedic medicine, Salacia reticulata is known to be useful against various metabolic diseases, including diabetes and obesity. In this study, we attempted to clarify the antiobesity mechanism and the safety of S. reticulata in vivo and in vit...
JOURNAL OF NATURAL MEDICINES 64(3) 281-287 2010年7月
To investigate the pharmacokinetics of [6]-shogaol, a pungent ingredient of Zingiber officinale Roscoe, the pharmacokinetic parameters were determined by using (14)C-[6]-shogaol (labeled compound) and [6]-shogaol (non-labeled compound). When the l...
Eri Otsuka Hiroyuki Abe Masaki Aburada Makoto Otsuka
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY 36(7) 839-844 2010年7月
Background: A suppository dosage form has a rapid effect on therapeutics, because it dissolves in the rectum, is absorbed in the bloodstream, and passes the hepatic metabolism. However, the dosage form is unstable, because a suppository is made in...
JOURNAL OF NATURAL MEDICINES 64(3) 266-274 2010年7月
In Ayurvedic medicine, Salacia reticulata is known to be useful against various metabolic diseases, including diabetes and obesity. In this study, we attempted to clarify the antiobesity mechanism and the safety of S. reticulata in vivo and in vit...
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