Molecular oxygen (O(2)) was successfully employed as a reoxidant in cyclizations of thiobenzanilides 1a-s through a palladium-catalyzed C-H functionalization/intramolecular C-S bond formation process, leading to an efficient, green method for the ...
Kiyofumi Inamoto   Mitsugu Shiraishi   Kou Hiroya   Takayuki Doi   
SYNTHESIS-STUTTGART (18) 3087-3090 2010年9月 [査読有り]
Desulfurization of thioamides was accomplished using a semicatalytic amount of Bu(4)NBr. The corresponding amides were obtained in high yields, with good functional group compatibility.
The C2-side chain hydroxyl group of 1,3-cycloalkanedione discriminates between two ketones depending on its chirality. It chooses one ketone to form hydrogen bond with the oxygen atom of the TBDPS-oxymethyl group, but chooses the other ketone upon...
Kiyofumi Inamoto   Tadataka Saito   Kou Hiroya   Takayuki Doi   
JOURNAL OF ORGANIC CHEMISTRY 75(11) 3900-3903 2010年6月 [査読有り]
A catalytic synthetic approach For the synthesis of nolinone compounds through a Pd-catalyzed C(sp(2))-H functionalization/intramolecular amidation sequence is described. The cyclization process efficiently proceeds in the presence of a catalytic ...