Kiyofumi Inamoto Tadataka Saito Mika Katsuno Takao Sakamoto Kou Hiroya
ORGANIC LETTERS 9(15) 2931-2934 2007年7月 [査読有り]
A method for the catalytic C-H activation of hydrazone compounds followed by intramolecular amination is described. It requires the use of a catalytic amount of Pd(OAc)(2) in the presence of Cu(OAc)(2) and AgOCOCF3, which efficiently effects the c...
Syntheses of 3-substituted indazoles and benzoisoxazoles were efficiently accomplished with the aid of Pd-catalyzed intramolecular carbon-nitrogen and carbon-oxygen bond formations. The catalyst system described herein allows the cyclization to pr...
We systematically investigated, for the first time, the relationship between regioselectivity and acid/base effects in the cyclization reactions between carboxylic acids and carbon-carbon triple bonds. We found novel acid- and base-promoted cycliz...
The DE ring system of (20S)-camptothecin had been prepared from commercially available nicotinic acid in six steps utilizing the nucleophilic addition reaction of the silyl ketene acetal to the pyridinone ring as a key step.
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