We found that AKT1, a primary effector molecule of PI3K-AKT signaling, distinctively suppressed Toll-like receptor (TLR)-mediated MyD88-dependent and Toll/IL-1R domain-containing adaptor inducing IFN-β (TRIF)-dependent signaling by inhibiting NF-κ...
We incubated tomonts of Cryptocaryon irritans in a hypoxic seawater environment (1.4–1.7 mg/L O2) (low dissolved oxygen
DO) and examined their development using a acetocarmine whole-mount staining method we developed for nuclear staining. They sh...
Hongshu Chi   Patricia Taik   Emily J. Foley   Alycia C. Racicot   Hilary M. Gray   Katherine E. Guzzetta   Hsin-Yun Lin   Yen -Ling Song   Che-Huang Tung   Kosuke Zenke   Tomoyoshi Yoshinaga   Chao-Yin Cheng   Wei-Jen Chang   Hui Gong   
MOLECULAR PHYLOGENETICS AND EVOLUTION 112 47-52 2017年7月 [査読有り]
The ciliate protozoan Cryptocaryon irritans parasitizes marine fish and causes lethal white spot disease. Sporadic infections as well as large-scale outbreaks have been reported globally and the parasite's broad host range poses particular threat ...
We investigated the development of the macronucleus of Cryptocaryon irritans, and the ingestion and digestion of host cells by the parasite. All developmental stages of the parasite except the theront (trophont, protomont and tomont) were examined...
Kah Hui How   Kosuke Zenke   Tomoyoshi Yoshinaga   
AQUACULTURE 438 170-175 2015年3月 [査読有り]
Cryptocaryon irritans is a parasitic ciliate that causes major economic losses in marine fish aquaculture globally. Despite the wide array of treatment methods, control of cryptocaryoniasis is still very challenging, especially in food fish cultur...