工藤敏之

研究者氏名	工藤敏之
	クドウトシユキ
URL
所属	武蔵野大学
部署	薬学部薬学科
職名	講師
学位	学士(星薬科大学), 修士(星薬科大学大学院), 博士(星薬科大学大学院)
J-Global ID	201701007072398063

研究キーワード

薬物動態・代謝学

研究分野

ライフサイエンス / 医療薬学 /

経歴

2015年4月

現在

武蔵野大学薬学部薬学科講師

2010年4月

2015年3月

武蔵野大学薬学部薬学科助教

2010年4月

2015年3月

武蔵野大学大学院薬学研究科助教

2010年4月

2015年3月

武蔵野大学薬学部助教

学歴

2007年4月

2010年3月

星薬科大学大学院

2005年4月

2007年3月

星薬科大学大学院

2001年4月

2005年3月

星薬科大学薬学部

2001年3月

私立市川高等学校

委員歴

2022年4月

現在

日本薬剤学会出版委員会

2016年4月

現在

日本薬剤学会薬物相互作用FG 執行部

受賞

2014年1月

Drug Metabolism Division of ASPET, James R. Gillette Drug Metabolism Best Paper of 2013,Analysis of the Repaglinide Concentration Increase Produced by Gemfibrozil and Itraconazole Based on the Inhibition of the Hepatic Uptake Transporter and Metabolic Enzymes
Toshiyuki Kudo Akihiro Hisaka Yuichi Sugiyama Kiyomi Ito

2007年9月

第24回和漢医薬学会大会優秀発表賞受賞

論文

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Gastroprotective Effect of Enteral Nutrition Formula in Mice Injected Subcutaneously with Indomethacin.

Yoshiaki Yamagishi Rei Saiki Takeshi Yoshimi Toshiyuki Kudo Kiyomi Ito

Nutrients 13(9) 2021年9月

We have previously shown that two enteral nutrition formulas suppressed gastric lesions induced by the oral administration of indomethacin (IND) in mice. However, the mechanism of their protective effect is unknown. In this study, the effect of th...

Pharmacokinetics of CuGTSM, a Novel Drug Candidate, in a Mouse Model of Menkes Disease.

Yoshiaki Yamagishi Toshiyuki Kudo Masafumi Oyumi Yusuke Sakamoto Kazuki Takahashi Taiki Akashi Shohei Kobayashi Takeaki Kawakami Hitomi Goda Yasuhiro Sato Masakazu Mimaki Hiroko Kodama Mitsutoshi Munakata Kosho Makino Hideyo Takahashi Toshiro Fukami Kiyomi Ito

Pharmaceutical research 38(8) 1335-1344 2021年8月

PURPOSE: Menkes disease is a rare hereditary disease in which systemic deficiency of copper due to mutation of the ATP7A gene causes severe neurodegenerative disorders. The present parenteral drugs have limited efficacy, so there is a need for an ...

In vitro-in vivo extrapolation of metabolic clearance using human liver microsomes: factors showing variability and their normalization.

Keiichi Morita Motohiro Kato Toshiyuki Kudo Kiyomi Ito

Xenobiotica; the fate of foreign compounds in biological systems 50(9) 1064-1075 2020年9月 [査読有り]

In vitro-in vivo extrapolation (IVIVE) using human liver microsomes has been widely used to predict metabolic clearance, but some of the factors used in the process of prediction show variability for the same compound: notably, microsomal intrinsi...

Chorea-like symptoms and high blood concentration of ceftriaxone in a patient undergoing hemodialysis: A case report.

Yoshiaki Yokoyama Naoto Hosokawa Toshiyuki Kudo Hitomi Goda Kiyomi Ito Masanori Suzuki Ryohkan Funakoshi

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 26(3) 285-288 2020年3月 [査読有り]

Ceftriaxone (CTRX) is a third-generation cephalosporin commonly used to treat infections such as community-acquired pneumonia and urinary tract infections caused by mainly Gram-negative bacteria and some Gram-positive bacteria. Here, we report a c...

Study of the Inhibitory Effects of Enteral Nutrition Formula on Indomethacin-Induced Gastric Lesions in Mice.

Takeshi Yoshimi Yoshiaki Yamagishi Issei Kanegawa Megumi Suda Rei Saiki Ken-Ichiro Tanaka Hitomi Goda Toshiyuki Kudo Kiyomi Ito

Nutrients 11(12) 2019年12月 [査読有り]

We investigated the effects of enteral nutrition formula on non-steroidal anti-inflammatory drug (NSAID)-induced gastric lesions in mice. Male ICR mice aged 7-9 weeks old were fasted, then orally given either purified water, Mermed® One, or 2-fold...