Drug Metabolism Division of ASPET, James R. Gillette Drug Metabolism Best Paper of 2013,Analysis of the Repaglinide Concentration Increase Produced by Gemfibrozil and Itraconazole Based on the Inhibition of the Hepatic Uptake Transporter and Metabolic EnzymesToshiyuki Kudo Akihiro Hisaka Yuichi Sugiyama Kiyomi Ito
Drug metabolism and pharmacokinetics 26(6) 612-20 2011年 [査読有り]
The purpose of this study was to provide a pharmacokinetics/pharmacodynamics and toxicokinetics/toxicodynamics bridging of kinase inhibitors by identifying the relationship between their clinical and preclinical (rat, dog, and monkey) data on expo...
T. Kudo   T. Toda   T. Ushiki   K. Ohi   N. Ikarashi   W. Ochiai   K. Sugiyama   
XENOBIOTICA 40(4) 282-290 2010年4月 [査読有り]
1 The pharmacokinetics of drugs can change in diabetes mellitus and even among diabetics. They may differ between type I diabetes (T1DM) and type
2 diabetes (T2DM). 2 As triazolam was administered orally to Tsumura, Suzuki, obese, diabetes (TSOD) ...