The zinc finger CW (zf-CW) domain is a motif of about 60 residues that is frequently found in proteins involved in epigenetic regulation. Here, we determined the NMR solution structure of the zf-CW domain of the human zf-CW and PWWP domain contain...
JOURNAL OF MOLECULAR BIOLOGY 393(2) 478-495 2009年10月 [査読有り]
The Notch signaling pathway is critical for many developmental processes and requires complex trafficking of both Notch receptor and its ligands, Delta and Serrate. In Drosophila melanogaster, the endocytosis of Delta in the signal-sending cell is...
Helena Hernandez Olga V. Makarova Evgeny M. Makarov Nina Morgner Yutaka Muto Daniel Pomeranz Krummel Carol V. Robinson
PLOS ONE 4(9) e7202 2009年9月 [査読有り]
Most human protein-encoding genes contain multiple exons that are spliced together, frequently in alternative arrangements, by the spliceosome. It is established that U1 snRNP is an essential component of the spliceosome, in human consisting of RN...
NUCLEIC ACIDS RESEARCH 37(15) 5151-5166 2009年8月 [査読有り]
The CUG-binding protein 1 (CUG-BP1) is a member of the CUG-BP1 and ETR-like factors (CELF) family or the Bruno-like family and is involved in the control of splicing, translation and mRNA degradation. Several target RNA sequences of CUG-BP1 have b...
Kazuki Kurimoto Kanako Kuwasako Alan M. Sandercock Satoru Unzai Carol V. Robinson Yutaka Muto Shigeyuki Yokoyama
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 75(2) 360-372 2009年5月 [査読有り]
The human AU RNA binding protein/enoyl-Coenzyme A hydratase (AUH) is a 3-hydroxy-3-methylglutaconyl-CoA dehydratase in the leucine degradation pathway. It also possesses an RNA-binding activity to AUUU repeats, which involves no known conserved RN...
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