Body and excrement extracts from Dermatophagoides Prime were used to study stimulation of Toll-like receptors (TLRs). The excrement extract stimulated nuclear factor (NF)-kappa B-dependent reporter activity to an extent similar to lipopolysacchari...
Naina Shah   Montserrat Montes de Oca   Maria Jover-Cobos   Ken-ichi Tanamoto   Masashi Muroi   Kei-ichi Sugiyama   Nathan A. Davies   Rajeshwar P. Mookerjee   Dipok Kumar Dhar   Rajiv Jalan   
Strategies for the prevention of multiorgan dysfunction (MOD) in acetaminophen (APAP)-induced acute liver failure (ALF) are an unmet need. Our study tested the hypothesis that sterile inflammation induced by APAP in a mouse model would activate to...
PATHOGENS AND DISEASE 67(3) 199-205 2013年4月 [査読有り]
We investigated the difference in the effect of synthetic lipid A compounds on MyD88-dependent and -independent Toll-like receptor 4 (TLR4) signaling in mouse macrophage cells. At higher concentrations, Escherichia coli-type hexa-acylated lipid A ...
The ability of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) to discriminate laboratory-derived antibiotic-resistant bacterial strains of known genetic origin was examined. A computer-based cluster ana...