Shigeharu Fujita   Naomi Yamashita   Yasuyuki Ishii   Yumiko Sato   Kaori Sato   Kawori Eizumia   Tomohiro Fukaya   Risa Nozawa   Yukiko Takamoto   Naohide Yamashita   Masaru Taniguchi   Katsuaki Sato   
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 121(1) 95-104 2008年1月 [査読有り]
Background: Dendritic cells (DCs) are crucial for the induction of immunity and tolerance. Despite an improved understanding of the DC-mediated control of T(H)1-biased immunity, little is known about how DCs regulate T(H)2-mediated immunity.
Objec...
Allergology International 56(3) 241-247 2007年 [査読有り]
Background: β-agonists are frequently used as bronchodilators for asthma as not only a reliever but also a controller, and their utility has increased with the development of long-acting β2 selective drugs. Although anti-inflammatory effects of β2...
N Yamashita   H Tashimo   H Ishida   Y Matsuo   H Tamauchi   M Terashima   Yoshiwara, I   S Habu   K Ohta   
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 290(6) L1045-L1051 2006年6月 [査読有り]
The pathophysiological characteristics of bronchial asthma consist of chronic inflammation of airways, airway hyperresponsiveness, and bronchoconstriction. Studies have shown that T helper type 2 (Th2) cytokines produced by both T cells and mast c...
S Fujita   K Seino   K Sato   Y Sato   K Eizumi   N Yamashita   M Taniguchi   K Sato   
BLOOD 107(9) 3656-3664 2006年5月 [査読有り]
Bacterial infection triggers host inflammation through the activation of immune cells, leading to the elimination of bacteria. However, the regulatory mechanisms of the host inflammatory response remain unknown. Here we report that a subset of pot...