New red pigments were isolated from a lichen thallus, Lethariella sinensis by Wei & Jiang. The structures of the red pigments, rubrosinensiquinones A (1), B (2), and C (3), were determined by spectroscopic analyses.
Deng Huiqun   Cai Xiaofeng   Peng Jianxin   Hong Huazhu   Ichinose Koji   Li Aiying   
JOURNAL OF BASIC MICROBIOLOGY 50(3) 299-301 2010年6月 [査読有り]
Streptomyces sp. AM-7161 is a producer of an aromatic polyketide medermycin with strong antibacterial and antitumor activity. It has been inefficient to perform genetic manipulations in this strain, which heavily hinders the genetic analysis of so...
All known benzoisochromanequinone (BIQ) biosynthetic gene clusters carry a set of genes encoding a two-component monooxygenase homologous to the ActVA-ORF5/ActVB system for actinorhodin biosynthesis in Streptomyces coelicolor A3(2). Here, we condu...
A. R. Willems   K. Tahlan   T. Taguchi   K. Zhang   Z. Z. Lee   K. Ichinose   M. S. Junop   J. R. Nodwell   
JOURNAL OF MOLECULAR BIOLOGY 376(5) 1377-1387 2008年3月 [査読有り]
Actinorhodin, an antibiotic produced by Streptomyces coelicolor, is exported from the cell by the ActA efflux pump. actA is divergently transcribed from actR, which encodes a TetR-like transcriptional repressor. We showed previously that ActR repr...
A novel shunt product, actinoperylone, has been isolated from a deletion mutant of the actVA-ORF5 and ORF6 genes involved in the biosynthesis of a benzoisochromanequinone (BIQ) antibiotic actinorhodin (ACT) in Streptomyces coelicolor A3(2). Spectr...