Virus-encoded microRNAs (miRNAs) target viral and host mRNAs to repress protein production from viral and host genes, and regulate viral persistence, cell transformation, and evasion of the immune system. The present study demonstrated that simian...
Hepatology International 12(3) 254-261 2018年5月 [査読有り]
Background and aims: Tsumura-Suzuki obese diabetic (TSOD) is a good model of metabolic syndrome showing typical lesions found in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis, and develops spontaneous hepatic tumors with a high...
著者   Hijikata T   Nakamura A   Isokawa K   Imamura M   Yuasa K   Ishikawa R   Kohama K   Takeda S   Yorifuji H   
Background: Skeletal muscles are composed of heterogeneous collections of muscle fiber types, the arrangement of which contributes to a variety of functional capabilities in many muscle types. Furthermore, skeletal muscles can adapt individual myo...
K. Yuasa   M. Yoshimura   N. Urasawa   S. Ohshima   J. M. Howell   A. Nakamura   T. Hijikata   Y. Miyagoe-Suzuki   S. Takeda   
GENE THERAPY 14(17) 1249-1260 2007年9月
Using murine models, we have previously demonstrated that recombinant adeno-associated virus (rAAV)-mediated microdystrophin gene transfer is a promising approach to treatment of Duchenne muscular dystrophy (DMD). To examine further therapeutic ef...
著者:Kawakami Y, Kumagai K, Huijing PA, Hijikata T, Fukunaga T(担当:共著)
John Wiley & Sons, LTD. 2000年10月
骨格筋の運動や力学的特性に関するシンポジウムのプロシーディング。19. The length-force characteristics of human gastrocnemius and soleus muscles in vivo. .ヒトの腓腹筋とヒラメ筋の筋線維構築を解剖学的に明らかにし、さらに超音波画像によりこれら筋の筋線維の動きや力の特性を明らかにした。これら結果にもとづき、筋線維構築と筋線維の運動ならびに力の特性を比較検討した総説的論文。(筋線維構築の解析箇所で貢献している...