Virus-encoded microRNAs (miRNAs) target viral and host mRNAs to repress protein production from viral and host genes, and regulate viral persistence, cell transformation, and evasion of the immune system. The present study demonstrated that simian...
Hepatology International 12(3) 254-261 2018年5月 [査読有り]
Background and aims: Tsumura-Suzuki obese diabetic (TSOD) is a good model of metabolic syndrome showing typical lesions found in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis, and develops spontaneous hepatic tumors with a high...
T Hijikata   N Fujimaki   H Osawa   H Ishikawa   
BIOLOGY OF THE CELL 90(9) 629-639 1998年12月
It has been biochemically shown that dystrophin and alpha- and beta-dystroglycan form an oligomeric complex which links laminin, a component of the basement membrane, to components of the subsarcolemmal cytoskeleton in skeletal muscle fibers. In t...
Z Lin   T Hijikata   Z Zhang   J Choi   S Holtzer   HL Sweeney   H Holtzer   
DEVELOPMENTAL BIOLOGY 199(2) 291-308 1998年7月
To explore the roles of specific domains of sarcomeric a-actinin (s-alpha-aetinin) in the assembly and maintenance of striated myofibrils, myogenic cultures were transfected with four MYC-tagged s-alpha-actinin peptides. They were: (1) full-length...
In the skeletal muscle fiber organization of many vertebrate muscles, serial arrangements or linkages of muscle fibers along the muscle or fascicle are commonly found. These serially linked muscle fibers employ distinct junctional morphologies fro...
T Hijikata   ZX Lin   S Holtzer   J Choi   HL Sweeney   H Holtzer   
CELL MOTILITY AND THE CYTOSKELETON 38(1) 54-74 1997年
To understand the multiple roles of alpha-actinin in the assembly of (1) Z bands in muscle, and (2) a variety of cytoskeletal structures in non-muscle cells, 4 sarcomeric alpha-actinin derived cDNAs tagged with a MYC epitope were constructed. The ...
著者:Kawakami Y, Kumagai K, Huijing PA, Hijikata T, Fukunaga T(担当:共著)
John Wiley & Sons, LTD. 2000年10月
骨格筋の運動や力学的特性に関するシンポジウムのプロシーディング。19. The length-force characteristics of human gastrocnemius and soleus muscles in vivo. .ヒトの腓腹筋とヒラメ筋の筋線維構築を解剖学的に明らかにし、さらに超音波画像によりこれら筋の筋線維の動きや力の特性を明らかにした。これら結果にもとづき、筋線維構築と筋線維の運動ならびに力の特性を比較検討した総説的論文。(筋線維構築の解析箇所で貢献している...