BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 410(3) 568-573 2011年7月
DNA double strand breaks (DSBs) induced by etoposide, an inhibitor of DNA topoisomerase II, are repaired mainly by non-homologous end joining (NHEJ). Unexpectedly, it was found that at high doses of etoposide, proteins involved in NHEJ, such as KU...
Kundu, L. R   Seki, M   Watanabe, N   Murofusi H   Furukohri, A   Waga, S   Score A. J   Blow, J. J   Horikoshi, M   nomoto, T   Tada, S   
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1813(3) 473-479 2011年3月
Rothmund-Thomson syndrome (RTS) is a rare genetic disorder characterized by premature aging, developmental abnormalities, and a predisposition to cancer. RTS is caused by mutations in the RECQL4 gene, which encodes one of the five human RecQ helic...
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 406(4) 649-655 2011年3月
L-type amino-acid transporter 1 (LAT1) is the first identified light chain of CD98 molecule, disulfide-linked to a heavy chain of CD98. Following cDNA cloning of chicken full-length LAT1, we have constructed targeting vectors for the disruption of...