BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1813(3) 473-479 2011年3月
Rothmund-Thomson syndrome (RTS) is a rare genetic disorder characterized by premature aging, developmental abnormalities, and a predisposition to cancer. RTS is caused by mutations in the RECQL4 gene, which encodes one of the five human RecQ helic...
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 406(4) 649-655 2011年3月
L-type amino-acid transporter 1 (LAT1) is the first identified light chain of CD98 molecule, disulfide-linked to a heavy chain of CD98. Following cDNA cloning of chicken full-length LAT1, we have constructed targeting vectors for the disruption of...
Lena R. Kundu   Yuji Kumata   Naoko Kakusho   Saori Watanabe   Asako Furukohri   Shou Waga   Masayuki Seki   Hisao Masai   Takemi Enomoto   Shusuke Tada   
NUCLEIC ACIDS RESEARCH 38(16) 5409-5418 2010年9月
Mcm2-7 is recruited to eukaryotic origins of DNA replication by origin recognition complex, Cdc6 and Cdt1 thereby licensing the origins. Cdc6 is essential for origin licensing during DNA replication and is readily destabilized from chromatin after...
Hirohito Endo   Satoshi Kawashima   Lui Sato   Mong Sing Lai   Takemi Enomoto   Masayuki Seki   Masami Horikoshi   
GENES TO CELLS 15(9) 945-958 2010年9月
Eukaryotic chromatin is regulated by chromatin factors such as histone modification enzymes, chromatin remodeling complexes and histone chaperones in a variety of DNA-dependent reactions. Among these reactions, transcription in the chromatin conte...
Lena R. Kundu   Yuji Kumata   Naoko Kakusho   Saori Watanabe   Asako Furukohri   Shou Waga   Masayuki Seki   Hisao Masai   Takemi Enomoto   Shusuke Tada   
NUCLEIC ACIDS RESEARCH 38(16) 5409-5418 2010年9月
Mcm2-7 is recruited to eukaryotic origins of DNA replication by origin recognition complex, Cdc6 and Cdt1 thereby licensing the origins. Cdc6 is essential for origin licensing during DNA replication and is readily destabilized from chromatin after...