The National Science Foundation, Presidential Award for Excellence in Science, Mathematics, and Engineering MentoringScience & Health Education Partnership
Trends in Neurosciences 39(8) 543-551 2016年8月 [査読有り]
Cerebrospinal fluid (CSF) continuously flows through the cerebral ventricles, a process essential for brain homeostasis. Multiciliated ependymal (E1) cells line the walls of the ventricles and contribute importantly to CSF flow through ciliary bea...
Neurochemical Research 41(1-2) 222-30 2016年2月 [査読有り]
In many animal species, the production of new neurons (neurogenesis) occurs throughout life, in a specialized germinal region called the ventricular-subventricular zone (V-SVZ). In this region, neural stem cells undergo self-renewal and generate n...
Journal of Neuroscience 35(31) 11153-11168 2015年8月 [査読有り]
Directional beating of ependymal (E) cells' cilia in the walls of the ventricles in the brain is essential for proper CSF flow. E cells display two forms of planar cell polarity (PCP): rotational polarity of individual cilium and translational pol...
Defects in ependymal (E) cells, which line the ventricle and generate cerebrospinal fluid flow through ciliary beating, can cause hydrocephalus. Dishevelled genes (Dvls) are essential for Wnt signaling, and Dvl2 has been shown to localize to the r...
How the mitosis of neuroepithelial stem cells is restricted to the apical ventricular area remains unclear. In zebrafish, the mosaic eyes(rw306) (moe/epb41I5(rw306)) mutation disrupts the interaction between the putative adaptor protein Moe and th...
Herranz-Pérez V   Nakatani J   Ishii M   Katada T   García-Verdugo JM   Ohata S   
Research Square 2021年12月
<title>Abstract</title>
The fusion protein of uncharacterised zinc finger translocation associated (ZFTA) and effector transcription factor of tumorigenic NF-kB signalling, RELA (ZFTA-RELA), is expressed in more than two-thirds of supratentorial ...