The National Science Foundation, Presidential Award for Excellence in Science, Mathematics, and Engineering MentoringScience & Health Education Partnership
Journal of Biochemistry 134(4) 551-558 2003年10月 [査読有り]
The plasticity of bone marrow cells (BMCs) remains controversial. The present study found that persistent injury induces efficient trans-differentiation of BMCs into functional hepatocytes. Mice with liver cirrhosis induced by carbon tetrachloride...
Journal of Biological Chemistry 278(19) 16595-16601 2003年5月 [査読有り]
Stress-activated protein kinase/c-Jun NH2-terminal kinase (SAPK/JNK), belonging to the mitogen-activated protein kinase family, plays an important role in stress signaling. SAPK/JNK activation requires the phosphorylation of both Thr and Tyr resid...
Mice lacking the stress-signaling kinase SEK1 die from embryonic day 10.5 (E10.5) to E12.5. Although a defect in liver formation is accompanied with the embryonic lethality of sek1(-/-) mice, the mechanism of the liver defect has remained unknown....
JOURNAL OF BIOLOGICAL CHEMISTRY 277(1) 366-371 2002年1月 [査読有り]
Ultraviolet (UV) irradiation stimulates stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/ JNK), which is a member of the mitogen-activated protein kinase (MAPK) superfamily and implicated in stress-induced apoptosis. UV also induces t...
Herranz-Pérez V   Nakatani J   Ishii M   Katada T   García-Verdugo JM   Ohata S   
Research Square 2021年12月
<title>Abstract</title>
The fusion protein of uncharacterised zinc finger translocation associated (ZFTA) and effector transcription factor of tumorigenic NF-kB signalling, RELA (ZFTA-RELA), is expressed in more than two-thirds of supratentorial ...