JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY 39 484-489 2017年6月 [査読有り]
Objectives: The adsorption kinetics of urine-like-toxin indole-3-acetic acid (IA) by spherical carbonaceous adsorbent (SC) was inhibited by competitive effect of atorvastatin calcium (AT).
Methods: Competitive effect of AT on the adsorption behavi...
INTERNATIONAL JOURNAL OF PHARMACEUTICS 524(1-2) 407-413 2017年5月 [査読有り]
In the pharmaceutical industry, the implementation of continuous manufacturing has been widely promoted in lieu of the traditional batch manufacturing approach. More specially, in recent years, the innovative concept of feed-forward control has be...
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY 37 74-80 2017年2月 [査読有り]
Carbonated apatite cement can be a potential biomaterial to be used as a drug carrier. We reported previously that sustainable release of simvastatin (SIM) from poly(lactic-co-glycolic acid) (PLGA) formulations could induce bone formation. The aim...
F. Shikata   S. Kimura   Y. Hattori   M. Otsuka   
RSC ADVANCES 7(61) 38307-38317 2017年 [査読有り]
We developed an in-line near-infrared spectroscopy (NIRS) monitoring method enabling a rapid and non-invasive analysis of granule properties during the high shear wet granulation (HSWG) process. Eleven batches were manufactured and used as the cal...
Bio-Medical Materials and Engineering 29(1) 1-14 2017年 [査読有り]
BACKGROUND: Since it can take an enormous amount of time and cost to discriminate counterfeit medicines by using conventional methods, counterfeit medicines has been spread in the world markets. OBJECTIVE: The purpose of this study was to develop ...
This project is the renovation of the lighting of a historic commercial building. The Orchard Road corner lot is a prime location for this fine landmark, a massive, but stately architectural structure with red eaves and Chinese inspired motifs. Ou...