Ajioka, I   T Akaike   Y Watanabe   
HEPATOLOGY 29(2) 396-402 1999年2月
A complex vascular network forms an important component of the liver architecture. This network is essential for the supply of oxygen and nutrients to cells and delivery of molecules for metabolic exchange. In this study, we attempted to construct...
Y Watanabe   Ajioka, I   T Akaike   
CYTOTECHNOLOGY 26(1) 65-78 1998年
The handling of hepatocytes, a major cell population in the liver is an important technique in both liver tissue engineering and hepatology. However these cells are so fragile that it has been impossible to harvest hepatocytes with high viability ...
Y Watanabe   H Osaki   T Akaike   
JOURNAL OF IMMUNOLOGY 159(10) 4840-4847 1997年11月
In the absence of a growth factor or an appropriate extracellular matrix (ECM), cells are arrested in the G(0)/G(1) phase, In this report, we demonstrate the evidence that TNF-alpha induced DNA synthesis of primary mouse hepatocytes in vitro by ac...