EUROPEAN JOURNAL OF IMMUNOLOGY 25(11) 3180-3186 1995年11月 [査読有り]
MRL-lpr mice are severely impaired in the Fas pathway of apoptosis induction. We here evaluate another pathway of apoptosis induction in MRL-Ipl mice which is protein kinase C (PKC) dependent. Despite the defect of the Fas pathway, apoptosis devel...
L MA MY PU AA AKHAND N OHATA K OHKUSU M KATO T IWAMOTO K ISOBE M HAMAGUCHI NAKASHIMA, I
JOURNAL OF CELLULAR BIOCHEMISTRY 59(1) 33-41 1995年9月 [査読有り]
Actions of monoiodoacetic acid (MIA) as a sulfhydryl reagent on the different stages of the T cell receptor (TCR)-mediated signal transduction were examined. MIA (1 mM) prevented anti-TCR (CD3) monoclonal antibody (mAb)-induced energy-dependent re...
MY PU L MA K OHKUSU KI ISOBE R TAGUCHI H IKEZAWA M HAMAGUCHI NAKASHIMA, I
FEBS LETTERS 361(2-3) 295-298 1995年3月 [査読有り]
The biological significance of the action of glycosylphosphatidylinositol (GPI)-anchored proteins in cell physiology and pathology when stimulated with their natural agonists is not known, Here me provide evidence that GPI-anchored proteins play a...
SMJ RAHMAN MY PU H YI K OHKUSU M KATO KI ISOBE R TAGUCHI H IKEZAWA NAKASHIMA, I
INFECTION AND IMMUNITY 63(1) 259-263 1995年1月 [査読有り]
Phosphatidylinositol-specific phospholipase C (PIPLC) from Bacillus thuringiensis, which cleaves phosphatidylinositol or glycosylphosphatidylinositol on the external cell surface to generate a second messenger for intracellular signal transduction...
学長
獣医学部