Miho Koizumi   Hikaru Eto   Mai Saeki   Masahide Seki   Tsuyoshi Fukushima   Shoichiro Mukai   Hisamitsu Ide   Yasuyuki Sera   Masayuki Iwasaki   Yutaka Suzuki   Atsushi Tohei   Yusuke Kishi   Hiroaki Honda   
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 36(12) e22662 2022年12月
Recent studies have demonstrated that epigenetic modifications are deeply involved in neurogenesis; however, the precise mechanisms remain largely unknown. To determine the role of UTX (also known as KDM6A), a demethylase of histone H3K27, in neur...
The Journal of veterinary medical science 84(3) 445-453 2022年3月 [査読有り]
A non-narcotic anesthetic combination (Me/Mi/Bu) of medetomidine (Me), midazolam (Mi), and butorphanol (Bu) has been recommended as the injectable anesthesia in mice. An original dose of Me/Mi/Bu (0.3/4.0/5.0 mg/kg) has provided sufficient anesthe...
The Journal of veterinary medical science 2020年10月 [査読有り]
Hypothermia during anesthetic events is a common adverse effect of anesthesia in laboratory animals. In particular, small rodents such as mice is susceptible to hypothermia during anesthetic events. Therefore, the animals will need additional ther...
A Tohei   H Sakamoto   H Kogo   
LIFE SCIENCES 69(3) 281-288 2001年6月
In the present study, we have examined whether the effects: of dexamethasone on follicle stimulating hormone (FSH) secretion were mediated by hypophysiotropic factors, and whether the increased levels of FSH induced by dexamethasone can stimulate ...
A Tohei   S Suda   K Taya   T Hashimoto   H Kogo   
EXPERIMENTAL BIOLOGY AND MEDICINE 226(3) 216-221 2001年3月
Effects of a xenobiotic estrogen, bisphenol A (BPA), on reproductive functions were investigated using adult male rats. BPA was dissolved into sesame oil and injected sc every day (1 mg/rat) for 14 days. Animals were killed by decapitation after t...
A Tohei   FX Shi   M Ozawa   K Imai   H Takahashi   Shimohira, I   T Kojima   G Watanabe   K Taya   
JOURNAL OF VETERINARY MEDICAL SCIENCE 63(1) 45-50 2001年1月
To elucidate the effects of ultrasound-guided transvaginal follicular aspiration, plasma concentrations of FSH, LH, inhibin, estradiol-17 beta and progesterone, and folliculogenesis were examined in Holstein cows. Four clinically healthy cows with...
A Tohei   M Matsuzaki   H Kogo   
NEUROENDOCRINOLOGY 73(1) 68-74 2001年1月
Pituitary adenylate cyclase activating polypeptide (PACAP) is a relatively new neu ro peptide, a nd it has a potent stimulatory effect on adenylate cyclase activity in rat pituitary cells. However, the role of PACAP in the physio logical control o...
Journal of Reproduction and Development 47(4) 211-216 2001年
Corticotropin releasing-hormone (CRH) is recognized as modulating luteinizing hormone releasing hormone (LH-RH) secretion at the medial preoptic area (MPOA), but the physiological significance of the effects of endogenous CRH on LH-RH secretion at...